Sein Jin
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View article: Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1
Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1 Open
Bak is a critical executor of apoptosis belonging to the Bcl-2 protein family. Bak contains a hydrophobic groove where the BH3 domain of proapoptotic Bcl-2 family members can be accommodated, which initiates its activation. Once activated,…
View article: Antioxidants prevent particulate matter-induced senescence of lung fibroblasts
Antioxidants prevent particulate matter-induced senescence of lung fibroblasts Open
View article: Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1
Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1 Open
Antiapoptotic B-cell lymphoma-2 (Bcl-2) proteins suppress apoptosis by interacting with proapoptotic regulators. They commonly contain a hydrophobic groove where the Bcl-2 homology 3 (BH3) domain of Bcl-2 family members or BH3 domain-conta…