Sein Lwin
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View article: An approach to neck pain in primary care
An approach to neck pain in primary care Open
Opening Vignette Sharon, a 57-year-old secretary, presented to your clinic with a 2-month history of atraumatic, progressively worsening neck pain with associated left arm pain and numbness. This was her first episode of such neck pain, an…
View article: Endovascular Coiling versus Neurosurgical Clipping in the Management of Aneurysmal Subarachnoid Haemorrhage in the Elderly: A Multicenter Cohort Study
Endovascular Coiling versus Neurosurgical Clipping in the Management of Aneurysmal Subarachnoid Haemorrhage in the Elderly: A Multicenter Cohort Study Open
Introduction The comparability of endovascular coiling over neurosurgical clipping has not been firmly established in elderly patients with aneurysmal subarachnoid haemorrhage (aSAH). Methods Data were obtained from all patients with aSAH …
View article: Service Interruption in HIV Care Amid COVID-19 Pandemic in Myanmar: Results From Analysis of Routine Program Data 2018-2022
Service Interruption in HIV Care Amid COVID-19 Pandemic in Myanmar: Results From Analysis of Routine Program Data 2018-2022 Open
Background COVID-19 pandemic disrupted organized HIV screening efforts, HIV testing and management worldwide, and the impact of these disruptions from private HIV care clinics have not been examined in Myanmar. PSI/Myanmar had adapted thro…
View article: Presenting characteristics, histological subtypes and outcomes of adult central nervous system tumours: retrospective review of a surgical cohort
Presenting characteristics, histological subtypes and outcomes of adult central nervous system tumours: retrospective review of a surgical cohort Open
Introduction: The most recent local study on the incidence of histological subtypes of all brain and spinal tumours treated surgically was published in 2000. In view of the outdated data, we investigated the presenting characteristics, his…
View article: Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study
Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study Open
Background The primary objective was to quantify changes in vascular micro-environment in spinal metastases (SM) patients treated with stereotactic body radiotherapy (SBRT) with multi-parametric dynamic contrast enhanced (DCE) magnetic res…
View article: A Roadmap for the Human Oral and Craniofacial Cell Atlas
A Roadmap for the Human Oral and Craniofacial Cell Atlas Open
Oral and craniofacial tissues are uniquely adapted for continuous and intricate functioning, including breathing, feeding, and communication. To achieve these vital processes, this complex is supported by incredible tissue diversity, vario…
View article: RADI-10. Is there any benefit for post-operative radiation in brain metastases? A systematic review and meta-analysis of Randomized controlled trials
RADI-10. Is there any benefit for post-operative radiation in brain metastases? A systematic review and meta-analysis of Randomized controlled trials Open
Purpose The benefits of adding upfront post-operative radiation (either whole-brain or cavity radiation) have been debated, particularly due to the possible detriment in cognition post-radiation. We sought to compare the efficacy and safet…
View article: RADI-06. Gamma knife surgery for brain stem metastases
RADI-06. Gamma knife surgery for brain stem metastases Open
Introduction Gamma Knife Surgery (GKS) is widely used for treatment of brainstem metastases (BSMs) with or without whole bran radiation therapy (WBRT). We hypothesized that BSMs treated with GKS using lower doses and omitting WBRT result i…
View article: RARE-01. MANAGEMENT AND OUTCOMES OF PAEDIATRIC CRANIOPHARYNGIOMA: A 15-YEAR EXPERIENCE IN SINGAPORE
RARE-01. MANAGEMENT AND OUTCOMES OF PAEDIATRIC CRANIOPHARYNGIOMA: A 15-YEAR EXPERIENCE IN SINGAPORE Open
BACKGROUND Craniopharyngiomas are rare embryonic malformations of the sellar region with high survival rates but high morbidity due to long-term sequelae caused by the location of the tumour. We summarise our institution’s experience on th…
View article: Thursday 17 October 2019
Thursday 17 October 2019 Open
Background: Large fraction sizes, used in SBRT, may activate novel ways of cell killing, such as endothelial apoptosis. 1However, this is poorly understood in the clinical setting.We performed a prospective cohort study including patients …
View article: Factors predicting outcomes in surgically treated pediatric traumatic brain injury
Factors predicting outcomes in surgically treated pediatric traumatic brain injury Open
Introduction: Traumatic brain injury (TBI) is a common presentation to the pediatric emergency department. Understanding factors that predict outcomes will be useful in clinical decision-making and prognostication. The objective of this st…
View article: Two Extraordinary Sellar Neuronal Tumors
Two Extraordinary Sellar Neuronal Tumors Open
In evaluating a sellar tumor with an uncommon morphology and neuroendocrine differentiation, an increased awareness of the unusual entities that may involve the sellar region and a judicious panel of immunohistochemical studies should impr…
View article: Factors associated with prolonged length of stay for elective hepatobiliary and neurosurgery patients: a retrospective medical record review
Factors associated with prolonged length of stay for elective hepatobiliary and neurosurgery patients: a retrospective medical record review Open
Our findings indicate that preoperative factors had the greatest association with prolonged LOS for HPB and NS elective surgeries even after adjusting for surgical complexity, suggesting that patient safety and quality of care may be impro…
View article: Intradural spinal tumors - a review of post operative outcomes between intramedullary and extramedullary tumors from a single institution’s experience
Intradural spinal tumors - a review of post operative outcomes between intramedullary and extramedullary tumors from a single institution’s experience Open
Intradural spinal tumors are rare and can be classified into extra or intra-medullary. They commonly present with symptoms such as intractable back pain or neurological deficits. We retrospectively reviewed 91 cases of intradural spinal tu…
View article: Delayed Breakdown of an Onlay Pericranial Flap Following Endoscopic Craniofacial Resection
Delayed Breakdown of an Onlay Pericranial Flap Following Endoscopic Craniofacial Resection Open
The pericranial flap is a well-vascularized, robust flap that is used to reconstruct anterior skull base defects following resection of skull base tumors. Failure of this flap is uncommon. However when it occurs, the consequences are poten…
View article: Body mass index and the risk of postoperative cerebrospinal fluid leak following transsphenoidal surgery in an Asian population
Body mass index and the risk of postoperative cerebrospinal fluid leak following transsphenoidal surgery in an Asian population Open
Elevated BMI is predictive of postoperative CSF leak following transsphenoidal procedures, even in an Asian population, where the definition of obesity differs from international standards. Thus, BMI should be considered in the clinical de…
View article: Improvement in cerebral hemodynamic parameters and outcomes after superficial temporal artery-middle cerebral artery bypass in patients with severe stenoocclusive disease of the intracranial internal carotid or middle cerebral arteries
Improvement in cerebral hemodynamic parameters and outcomes after superficial temporal artery-middle cerebral artery bypass in patients with severe stenoocclusive disease of the intracranial internal carotid or middle cerebral arteries Open
OBJECT Both the older and the recent extracranial-intracranial (EC-IC) bypass trials for symptomatic carotid occlusion failed to demonstrate a reduction in stroke recurrence. However, the role of superficial temporal artery (STA)-middle ce…