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View article: Investigation of MicroRNA-17 Expression, Tumor Necrosis Factor-α, and Interleukin-6 Levels in Lumbar Degenerative Disc Disease: Case–Control Study
Investigation of MicroRNA-17 Expression, Tumor Necrosis Factor-α, and Interleukin-6 Levels in Lumbar Degenerative Disc Disease: Case–Control Study Open
Background/Objectives: The aim of the study is to investigate the role of microRNA-17 (miRNA-17), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) in the pathogenesis of lumbar degenerative disc disease (LDDD). The goal is to …
View article: Evaluation of Serum Superoxide Dismutase Levels in Lumbar Degenerative Spinal Diseases: A Prospective Meta-analysis
Evaluation of Serum Superoxide Dismutase Levels in Lumbar Degenerative Spinal Diseases: A Prospective Meta-analysis Open
Background: The aim of this study was to evaluate the correlation between serum superoxide dismutase (SOD) enzyme levels and lumbar degenerative spinal diseases (LDSD).Materials and Methods: Ninety-four patients with LDSD and 64 patients w…
View article: Serum mirna-582-5p and mirna-363 as potential non-invasive biomarkers for glioblastoma multiforme
Serum mirna-582-5p and mirna-363 as potential non-invasive biomarkers for glioblastoma multiforme Open
High serum levels of miRNA-582-5p and miRNA-363 are associated with Glioblastoma Multiforme, and are potential biomarkers.
View article: Determination of<i>IDH1, IDH2, MGMT, TERT</i>and<i>ATRX</i>Gene Mutations in Glial Tumors
Determination of<i>IDH1, IDH2, MGMT, TERT</i>and<i>ATRX</i>Gene Mutations in Glial Tumors Open
Targeted NGS generates therapeutically meaningful information, providing better prognostic information than conventional histology. Our study shows that NGS provides important information on survival by helping to detect chromosomal change…
View article: A comparative study for glioma classification using deep convolutional neural networks
A comparative study for glioma classification using deep convolutional neural networks Open
Gliomas are a type of central nervous system (CNS) tumor that accounts for the most of malignant brain tumors. The World Health Organization (WHO) divides gliomas into four grades based on the degree of malignancy. Gliomas of grades I-II a…
View article: The Effect of Lutein on Ischemia-reperfusion-induced Vasculitic Neuropathic Pain and Neuropathy in Rats
The Effect of Lutein on Ischemia-reperfusion-induced Vasculitic Neuropathic Pain and Neuropathy in Rats Open
Lutein is potentially useful in the treatment of I/R-related neuropathy and neuropathic pain.
View article: Investigation of the Effects of MicroRNA-221 Expression Levels in Glioblastoma Multiforme Tumors
Investigation of the Effects of MicroRNA-221 Expression Levels in Glioblastoma Multiforme Tumors Open
Increased expression levels of miRNA-221 could be a biomarker for glial tumors.
View article: Multi-level anterior cervical decompression in multi-level cervical spondylotic myelopathy without extending the corpus resection: a cadaveric study of a novel surgical technique
Multi-level anterior cervical decompression in multi-level cervical spondylotic myelopathy without extending the corpus resection: a cadaveric study of a novel surgical technique Open
This study demonstrated that two more level decompression is possible with a single-level corpectomy in the cervical region using the new technique.
View article: The Effect of Rutin on Experimental Traumatic Brain Injury and Edema in Rats
The Effect of Rutin on Experimental Traumatic Brain Injury and Edema in Rats Open
Rutin might be effective in the treatment of TBI and TBI-related brain edema.
View article: Extremely rare complication of granulomatosis with polyangiitis
Extremely rare complication of granulomatosis with polyangiitis Open
The systemic vasculitis of the small-medium arteries, arterioles, venules and rarely large arteries that involves respiratory system and kidneys was defined as Granulomatosis with Polyangiitis (GPA) disease by Wegener in 1936. Intracranial…
View article: The Evaluation of Glutathione Reductase and Malondialdehyde Levels in Patients With Lumbar Disc Degeneration Disease
The Evaluation of Glutathione Reductase and Malondialdehyde Levels in Patients With Lumbar Disc Degeneration Disease Open
Oxidative stress mechanisms play a crucial role in disc degeneration and GR deficiency could be an eligible risk factor for LDDD.
View article: The Evaluation of Proteoglycan Levels and the Possible Role of <i>ACAN</i> Gene (c.6423T>C) Variant in Patients with Lumbar Disc Degeneration Disease
The Evaluation of Proteoglycan Levels and the Possible Role of <i>ACAN</i> Gene (c.6423T>C) Variant in Patients with Lumbar Disc Degeneration Disease Open
Our findings suggest that proteoglycan has emerged as a potential novel biomarker which might be used for prediction of LDDD risk.
View article: Spinal Tuberculosis Mimicking Failed Back Surgery
Spinal Tuberculosis Mimicking Failed Back Surgery Open
BACKGROUND The aim of this study was to draw attention to rare spinal infections in recurrent failed spinal surgeries. CASE REPORT A 59-year-old female was admitted to the hospital for back pain, which was assessed as a 9 on the visual ana…
View article: Tumor Necrosis Factor-Alpha (TNF-α-308 G>A) Polymorphism in High-grade Gliomas
Tumor Necrosis Factor-Alpha (TNF-α-308 G>A) Polymorphism in High-grade Gliomas Open
TNF genotype frequency comparison between the patients and controls was not statistically significant in the Turkish population tested. However, further studies are needed to evaluate the genotype and phenotype correlations in large cohort…
View article: Association of rs2228570 polymorphism of vitamin d receptor gene with lumbar degenerative disc disease
Association of rs2228570 polymorphism of vitamin d receptor gene with lumbar degenerative disc disease Open
VDR rs2228570 AG genotype is at a decreased risk and the GG genotype is at an increased risk of LDDD in the Turkish population. Since genetic polymorphisms often show ethnic differences, further functional studies are needed to evaluate th…
View article: The size of posterior urethrovesical angle change affects the success of sling operations
The size of posterior urethrovesical angle change affects the success of sling operations Open
Purpose: To analyze the effect of the size of posterior urethrovesical angle (PUVA) changes on the efficacy of surgical incontinence treatments. Materials and Methods: This study included 126 patients with stress urinary incontinence. The …
View article: Encephalocraniocutaneous Lipomatosis: Haberland Syndrome
Encephalocraniocutaneous Lipomatosis: Haberland Syndrome Open
BACKGROUND Encephalocraniocutaneous lipomatosis (ECCL) was first announced as a new type of ectomesodermal dysgenesis in 1970 by Haberland and Perou. ECCL was first described in 1970, and approximately 60 cases have been reported since the…
View article: Isolated C5 Vertebrae Dislocation with Trauma: An Extremely Rare Case of Isolated C5 Dislocation
Isolated C5 Vertebrae Dislocation with Trauma: An Extremely Rare Case of Isolated C5 Dislocation Open
BACKGROUND Total spondylolisthesis, or dislocation of 1 cervical vertebrae, is only caused by high-energy trauma and is usually fatal. Cervical spine fractures and dislocations often cause 3-column structural damage to the cervical spine, …
View article: Thoracic Epidural Hematoma Complicating Vertebroplasty
Thoracic Epidural Hematoma Complicating Vertebroplasty Open
BACKGROUND Percutaneous vertebroplasty procedures are commonly used to treat vertebral fractures. These techniques may be associated with major complications. CASE REPORT We present here a case of a 64-year-old female patient with T9 and T…
View article: Role of Caspase-9 Gene Ex5+32 G>A (rs1052576) Variant in Susceptibility to Primary Brain Tumors
Role of Caspase-9 Gene Ex5+32 G>A (rs1052576) Variant in Susceptibility to Primary Brain Tumors Open
CASP-9 (rs1052576) mutant A allele seems to be a protective factor for glioma brain tumor. Future studies with a larger sample size will clarify the possible roles of CASP-9 gene in the etiology and progression of primary brain tumors.
View article: Calcified Cerebellar Ganglioglioma in an Adult Patient: Case Report
Calcified Cerebellar Ganglioglioma in an Adult Patient: Case Report Open
ÖZETGangliogliom, genellikle çocuklarda gözlenmekte olup, sinir sisteminin nadir tümörüdür.Hem nöronal hem de glial hücrelerden oluşan mikst tipte kitledir.Erişkin yaşta oldukça nadirdir.Sıklıkla supratentorial olarak yerleşim gösteren bu …
View article: Vertebral augmentation by kyphoplasty and vertebroplasty: 8 years experience outcomes and complications
Vertebral augmentation by kyphoplasty and vertebroplasty: 8 years experience outcomes and complications Open
Percutaneous vertebroplasty and balloon kyphoplasty are both effective and safe minimally invasive procedures for the stabilization of VCFs. However, complications should be kept in mind during decision making.
View article: Neuroprotective effects of pregabalin against spinal cord ischemia-reperfusion injury in rats
Neuroprotective effects of pregabalin against spinal cord ischemia-reperfusion injury in rats Open
Pregabalin pre-treatmet and MP treatment both has neuroprotective effect on I/R injury by decreasing caspase dependant apoptosis, and inflammatory and oxidative stress markers. In addition, pregabalin pre-treatment had better clinical effe…
View article: Supra- and Infratentorial Cystic Metastases of Breast Cancer: Case Report
Supra- and Infratentorial Cystic Metastases of Breast Cancer: Case Report Open
ÖZETMeme kanserinin kranial metastazları; kemik, dura veya beyin