Semsa Gogcu
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View article: Maternal Cardiometabolic Risk Factors in Pregnancy and Offspring Blood Pressure at Age 2 to 18 Years
Maternal Cardiometabolic Risk Factors in Pregnancy and Offspring Blood Pressure at Age 2 to 18 Years Open
Importance Higher blood pressure in early life may signal cardiovascular disease over the life course, but determinants of blood pressure in early life are poorly understood. Objective To examine the association of maternal cardiometabolic…
View article: Standardized Classification of Infants With Robin Sequence Using MicroNAPS: The Impact of Syndromes and Comorbidities
Standardized Classification of Infants With Robin Sequence Using MicroNAPS: The Impact of Syndromes and Comorbidities Open
Background: MicroNAPS, a classification for infants with Robin sequence (RS) intended to guide treatment decisions, consists of 5 elements: micrognathia, nutrition, airway, palatal clefting, and syndromes/comorbidities. Scoring of the firs…
View article: Newborn blood DNA methylation and childhood asthma: findings from the ECHO program
Newborn blood DNA methylation and childhood asthma: findings from the ECHO program Open
Background DNA methylation (DNAm) at birth has been linked to childhood asthma in epigenome-wide association studies (EWASs). However, existing EWASs have limited representation of non-European and extremely preterm participants and have n…
View article: The intergenerational metabolic-cardiovascular life course: maternal body mass index (BMI), offspring BMI, and blood pressure of adolescents born extremely preterm
The intergenerational metabolic-cardiovascular life course: maternal body mass index (BMI), offspring BMI, and blood pressure of adolescents born extremely preterm Open
View article: Maternal and psychosocial antecedents of anxiety and depression in extremely low gestational age newborns at age 15 years
Maternal and psychosocial antecedents of anxiety and depression in extremely low gestational age newborns at age 15 years Open
The prevalence of many psychiatric symptoms, including anxiety and depression, is higher in individuals born extremely preterm (EP) than in term-born individuals during childhood and adolescence. In this prospective study of adolescents bo…
View article: Maternal and psychosocial antecedents of anxiety and depression in extremely low gestational age newborns at age 15 years
Maternal and psychosocial antecedents of anxiety and depression in extremely low gestational age newborns at age 15 years Open
Objectives The prevalence of many psychiatric symptoms, including anxiety and depression, is higher in individuals born extremely preterm (EP) than in term-born individuals during childhood and adolescence. In this prospective study of ado…
View article: Advocating for the inclusion of kidney health outcomes in neonatal research: best practice recommendations by the Neonatal Kidney Collaborative
Advocating for the inclusion of kidney health outcomes in neonatal research: best practice recommendations by the Neonatal Kidney Collaborative Open
Acute kidney injury (AKI) occurs in nearly 30% of sick neonates. Chronic kidney disease (CKD) can be detected in certain populations of sick neonates as early as 2 years. AKI is often part of a multisystem syndrome that negatively impacts …
View article: Psychiatric Outcomes, Functioning, and Participation in Extremely Low Gestational Age Newborns at Age 15 Years
Psychiatric Outcomes, Functioning, and Participation in Extremely Low Gestational Age Newborns at Age 15 Years Open
View article: Retinopathy of prematurity and neurodevelopmental outcome and quality of life at 10 years of age
Retinopathy of prematurity and neurodevelopmental outcome and quality of life at 10 years of age Open
Objective In a cohort of 10-year-old children born extremely preterm, we evaluated the hypothesis that increasing severity of retinopathy of prematurity (ROP) is associated with increasing frequency of unfavorable neurodevelopmental and qu…
View article: Social determinants of health rather than race impact health-related quality of life in 10-year-old children born extremely preterm
Social determinants of health rather than race impact health-related quality of life in 10-year-old children born extremely preterm Open
Background Reducing healthcare disparities among children is extremely important given the potential impact of these disparities on long-term health-related quality of life (HRQL). Race and parental socioeconomic status (SES) are associate…
View article: Contemporary definitions of infant growth failure and neurodevelopmental and behavioral outcomes in extremely premature infants at two years of age
Contemporary definitions of infant growth failure and neurodevelopmental and behavioral outcomes in extremely premature infants at two years of age Open
Background Associations of 2-year neurodevelopmental and behavioral outcomes with growth trajectories of preterm infants are unknown. Methods This secondary analysis of a preterm cohort examined in-hospital and discharge to 2-year changes …
View article: Social determinants of health rather than race impact health-related quality of life in 10-year-old children born extremely preterm
Social determinants of health rather than race impact health-related quality of life in 10-year-old children born extremely preterm Open
Background: Reducing healthcare disparities among children is extremely important given the potential impact of these disparities on long-term health-related quality of life (HRQL). Race and parental socioeconomic status (SES) are associat…
View article: Health-related quality of life at age 10 years in children born extremely preterm
Health-related quality of life at age 10 years in children born extremely preterm Open
ObjectiveTo evaluate the association between prenatal maternal health and socioeconomic status (SES) and health-related quality of life (QoL) among 10-year-old children born extremely preterm.Design/ methodsRetrospective analysis of the Ex…
View article: P202: Effectiveness of universal, first-tier genome sequencing for critically ill infants on extracorporeal membrane oxygenation
P202: Effectiveness of universal, first-tier genome sequencing for critically ill infants on extracorporeal membrane oxygenation Open
Genome sequencing (GS) has been increasingly utilized as a first-tier test for acutely ill infants in intensive care units (ICUs) to improve clinical outcomes. Yet, there remains significant uncertainty about the timing and selection of in…
View article: Association Between Urinary Biomarkers and CKD in Extremely Low Gestational Age Neonates
Association Between Urinary Biomarkers and CKD in Extremely Low Gestational Age Neonates Open
View article: Spectrum of Disease in Hospitalized Newborns with Congenital Micrognathia: A Cohort of 3,236 Infants at North American Tertiary-Care Intensive Care Units
Spectrum of Disease in Hospitalized Newborns with Congenital Micrognathia: A Cohort of 3,236 Infants at North American Tertiary-Care Intensive Care Units Open
View article: Neurodevelopmental and behavioral outcomes of very preterm infants: latent profile analysis in the Environmental influences on Child Health Outcomes (ECHO) Program
Neurodevelopmental and behavioral outcomes of very preterm infants: latent profile analysis in the Environmental influences on Child Health Outcomes (ECHO) Program Open
View article: Evaluation of pediatric epigenetic clocks across multiple tissues
Evaluation of pediatric epigenetic clocks across multiple tissues Open
Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination. Results Our study used data from seven tissue types …
View article: Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns
Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns Open
View article: Contemporary Definitions of Infant Growth Failure and Neurodevelopmental and Behavioral Outcomes in Extremely Premature Infants at Two Years of Age
Contemporary Definitions of Infant Growth Failure and Neurodevelopmental and Behavioral Outcomes in Extremely Premature Infants at Two Years of Age Open
Introduction: The association of 2-year neurodevelopmental and behavioral outcomes with in-hospital or post-discharge growth failure (GF) using contemporary definitions for preterm infants is unknown. Methods In a secondary analysis of a p…
View article: COVID-19 Stress and Child Behavior: Examining Discrimination and Social Support in Racially Diverse ECHO Cohorts
COVID-19 Stress and Child Behavior: Examining Discrimination and Social Support in Racially Diverse ECHO Cohorts Open
View article: Maternal stress and early childhood BMI among US children from the Environmental influences on Child Health Outcomes (ECHO) program
Maternal stress and early childhood BMI among US children from the Environmental influences on Child Health Outcomes (ECHO) program Open
View article: Provision and availability of genomic medicine services in Level IV neonatal intensive care units
Provision and availability of genomic medicine services in Level IV neonatal intensive care units Open
View article: Additional file 1 of Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns
Additional file 1 of Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns Open
Additional file 1: Table S1. Provides a list of all significant CpG loci identified in the analysis presented in this manuscript.
View article: P378: Inter-center variation in the availability and provision of genetic medicine services in Level IV NICUs*
P378: Inter-center variation in the availability and provision of genetic medicine services in Level IV NICUs* Open
View article: Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns
Sexually dimorphic methylation patterns characterize the placenta and blood from extremely preterm newborns Open
Background Health outcomes among children born prematurely are known to be sexually dimorphic, with male infants often more affected, yet the mechanism behind this observation is not clear. CpG methylation levels in the placenta and blood …
View article: Predicting 2-year neurodevelopmental outcomes in extremely preterm infants using graphical network and machine learning approaches
Predicting 2-year neurodevelopmental outcomes in extremely preterm infants using graphical network and machine learning approaches Open
Supported by the National Institute of Neurological Disorders and StrokeU01NS077953 and U01NS077955.
View article: Table of Contents
Table of Contents Open
View article: Long-Term Outcome of Necrotizing Enterocolitis and Spontaneous Intestinal Perforation
Long-Term Outcome of Necrotizing Enterocolitis and Spontaneous Intestinal Perforation Open
OBJECTIVES Necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) are complications in preterm infants associated with high morbidity, mortality, impaired growth, and neurodevelopmental (ND) outcomes. Few studies have…
View article: Growth During Infancy After Extremely Preterm Birth: Associations with Later Neurodevelopmental and Health Outcomes
Growth During Infancy After Extremely Preterm Birth: Associations with Later Neurodevelopmental and Health Outcomes Open