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View article: Prophylactic Anticoagulation and Thrombosis in Hospitalized Patients with Clinically Stable COVID-19 at Admission: From the Practice-Based Observational Study
Prophylactic Anticoagulation and Thrombosis in Hospitalized Patients with Clinically Stable COVID-19 at Admission: From the Practice-Based Observational Study Open
Yugo Yamashita, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino , et al. · 2023
Objectives: The potential benefit of routine prophylactic anticoagulation for all hospitalized patients with clinically stable coronavirus disease 2019 (COVID-19) is still controversial. Method: The CLOT-COVID Study was a mul…
View article: Clinical Features Comparing Arterial Thrombosis and Venous Thromboembolism in Hospitalized Patients with COVID-19: Result from the CLOT-COVID Study
Clinical Features Comparing Arterial Thrombosis and Venous Thromboembolism in Hospitalized Patients with COVID-19: Result from the CLOT-COVID Study Open
Michihisa Umetsu, Hajime Kanamori, Koji Murakami, Takuya Shiga, Sen Yachi , et al. · 2023
Objectives: This study aimed to investigate the clinical features of arterial thrombosis and venous thromboembolism (VTE) in coronavirus disease 2019 (COVID-19). Methods: The CLOT-COVID Study was a retrospective, multicenter …
View article: Risk Factors and Impact on Outcomes of Thrombosis in Patients with COVID-19 in Japan: From the CLOT-COVID Study
Risk Factors and Impact on Outcomes of Thrombosis in Patients with COVID-19 in Japan: From the CLOT-COVID Study Open
Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino, Junichi Nakamura , et al. · 2023
Objectives: The relationship between the thrombotic event and prognosis in patients with coronavirus disease 2019 (COVID-19) has not yet been fully investigated in Japan. Our study aimed to investigate the clinical outcomes and risk…
View article: Real-World Management of Pharmacological Thromboprophylactic Strategies for COVID-19 Patients in Japan
Real-World Management of Pharmacological Thromboprophylactic Strategies for COVID-19 Patients in Japan Open
Hiroya Hayashi, Yasuhiro Izumiya, Daiju Fukuda, Fumiaki Wakita, Yasumitsu Mizobata , et al. · 2022
View article: Mortality-associated Risk Factors in Hospitalized COVID-19 Patients in Japan: Findings of the CLOT-COVID Study
Mortality-associated Risk Factors in Hospitalized COVID-19 Patients in Japan: Findings of the CLOT-COVID Study Open
Makoto Takeyama, Sen Yachi, Yuji Nishimoto, Ichizo Tsujino, Junichi Nakamura , et al. · 2022
This large-scale observational study in Japan identified several independent risk factors for mortality in hospitalized patients with COVID-19 that could facilitate appropriate risk stratification of patients with COVID-19.
View article: Incidence, risk factors, and clinical impact of major bleeding in hospitalized patients with COVID-19: a sub-analysis of the CLOT-COVID Study
Incidence, risk factors, and clinical impact of major bleeding in hospitalized patients with COVID-19: a sub-analysis of the CLOT-COVID Study Open
Junichi Nakamura, Ichizo Tsujino, Sen Yachi, Makoto Takeyama, Yuji Nishimoto , et al. · 2022
Background The coronavirus disease 2019 (COVID-19) causes extensive coagulopathy and a potential benefit of anticoagulation therapy has been documented for prevention of thromboembolic events. Bleeding events has also been reported as a no…
View article: Influence of obesity on incidence of thrombosis and disease severity in patients with COVID-19: From the CLOT-COVID study
Influence of obesity on incidence of thrombosis and disease severity in patients with COVID-19: From the CLOT-COVID study Open
Yoshito Ogihara, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino , et al. · 2022
View article: Significant Impact of Age on Mortality and Non-significant Impact of Age on Thrombosis and Major Bleeding in Patients with COVID-19: From the CLOT-COVID Study
Significant Impact of Age on Mortality and Non-significant Impact of Age on Thrombosis and Major Bleeding in Patients with COVID-19: From the CLOT-COVID Study Open
Yugo Yamashita, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino , et al. · 2022
In the current large observational study of patients with COVID-19, the risk of mortality became markedly higher with increased age. However, the risks of thrombosis and major bleeding did not necessarily increase as age increases, which s…
View article: Association Between the Development of Thrombosis and Worsening of Disease Severity in Patients With Moderate COVID-19 on Admission ― From the CLOT-COVID Study ―
Association Between the Development of Thrombosis and Worsening of Disease Severity in Patients With Moderate COVID-19 on Admission ― From the CLOT-COVID Study ― Open
Satoshi Ikeda, Yuki Ueno, Koji Maemura, Sen Yachi, Makoto Takeyama , et al. · 2022
Approximately 20% of patients with moderate COVID-19 had worsened severity during hospitalization. Increased age, diabetes, D-dimer levels >1.0 μg/mL on admission, and the development of thrombosis during hospitalization were significantly…
View article: Therapeutic-Dose vs. Prophylactic-Dose Anticoagulation Therapy for Critically Ill Patients With COVID-19 in a Practice-Based Observational Study
Therapeutic-Dose vs. Prophylactic-Dose Anticoagulation Therapy for Critically Ill Patients With COVID-19 in a Practice-Based Observational Study Open
Yugo Yamashita, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino , et al. · 2022
Among a cohort of critically ill patients with COVID-19, approximately half received therapeutic-dose anticoagulation, although it did not show a potential benefit compared with prophylactic-dose anticoagulation.
View article: Incidence, Risk Factors, and Clinical Impact of Major Bleeding in Hospitalized Patients with COVID-19: A Sub-analysis of the CLOT-COVID Study
Incidence, Risk Factors, and Clinical Impact of Major Bleeding in Hospitalized Patients with COVID-19: A Sub-analysis of the CLOT-COVID Study Open
Junichi Nakamura, Ichizo Tsujino, Sen Yachi, Makoto Takeyama, Yuji Nishimoto , et al. · 2022
Background: The coronavirus disease 2019 (COVID-19) causes extensive coagulopathy and a potential benefit of anticoagulation therapy has been documented for prevention of thromboembolic events. Bleeding events has also been reported as a n…
View article: The current status of thrombosis and anticoagulation therapy in patients with COVID-19 in Japan: From the CLOT-COVID study
The current status of thrombosis and anticoagulation therapy in patients with COVID-19 in Japan: From the CLOT-COVID study Open
Yuji Nishimoto, Sen Yachi, Makoto Takeyama, Ichizo Tsujino, Junichi Nakamura , et al. · 2022
View article: Influence of sex on development of thrombosis in patients with COVID-19: From the CLOT-COVID study
Influence of sex on development of thrombosis in patients with COVID-19: From the CLOT-COVID study Open
Yugo Yamashita, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino , et al. · 2022
View article: D-Dimer Values and Venous Thromboembolism in Patients With COVID-19 in Japan ― From the CLOT-COVID Study ―
D-Dimer Values and Venous Thromboembolism in Patients With COVID-19 in Japan ― From the CLOT-COVID Study ― Open
Nobutaka Ikeda, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino , et al. · 2022
Background: To date, there are no large-scale data on the association between D-dimer levels at admission and the occurrence of venous thromboembolism (VTE) in Japanese patients with coronavirus disease 2019 (COVID-19).
View article: The Association between the Development of Thrombosis and Worsening of Disease Severity in Patients with Moderate COVID-19 on Admission: From the CLOT-COVID Study
The Association between the Development of Thrombosis and Worsening of Disease Severity in Patients with Moderate COVID-19 on Admission: From the CLOT-COVID Study Open
Satoshi Ikeda, Yuki Ueno, Koji Maemura, Sen Yachi, Makoto Takeyama , et al. · 2022
View article: Influence of Sex on Development of Thrombosis in Patients with COVID-19: From the CLOT-COVID Study
Influence of Sex on Development of Thrombosis in Patients with COVID-19: From the CLOT-COVID Study Open
Yugo Yamashita, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino , et al. · 2022
View article: Prophylactic Anticoagulation and Thrombosis in Hospitalized Patients with Clinically Stable COVID-19 at Admission: From the CLOT-COVID Study
Prophylactic Anticoagulation and Thrombosis in Hospitalized Patients with Clinically Stable COVID-19 at Admission: From the CLOT-COVID Study Open
Yugo Yamashita, Sen Yachi, Makoto Takeyama, Yuji Nishimoto, Ichizo Tsujino , et al. · 2022
View article: Relation between Success Placement of Central Venous Port and Left Brachiocephalic Vein Stenosis
Relation between Success Placement of Central Venous Port and Left Brachiocephalic Vein Stenosis Open
Sen Yachi, Tetsuya Saito, Eri Yoshida, Makoto Takeyama, Seiji Ayabe · 2020
【目的】CVポート留置術の成否と左腕頭静脈狭窄との関連を調査した。【方法】対象149例の手技成否と術前CTでの腕頭静脈周辺の解剖学的な関連を調査した。【結果】左側アプローチ中9.5%がカテーテル不通過であった。カテーテル不通過群は通過群と比べ,胸骨大動脈間距離,左腕頭静脈の径および走行角度が有意に小さかった。【結論】狭小な胸骨大動脈距離,左腕頭静脈の狭窄および急峻な走行角度が,カテーテル通過困難の要因であると考えられた。




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