Seng Kong Tham
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View article: Antiviral Strategies Targeting Enteroviruses: Current Advances and Future Directions
Antiviral Strategies Targeting Enteroviruses: Current Advances and Future Directions Open
Enteroviruses, a diverse genus within the Picornaviridae family, are responsible for a wide range of human infections, including hand, foot, and mouth disease, respiratory disease, aseptic meningitis, encephalitis, myocarditis, and acute f…
View article: Correction: Revolutionizing immunization: a comprehensive review of mRNA vaccine technology and applications
Correction: Revolutionizing immunization: a comprehensive review of mRNA vaccine technology and applications Open
View article: mRNA Vaccine Development in the Fight Against Zoonotic Viral Diseases
mRNA Vaccine Development in the Fight Against Zoonotic Viral Diseases Open
Zoonotic diseases are transmitted from animals to humans, and they impose a significant global burden by impacting both animal and human health. It can lead to substantial economic losses and cause millions of human deaths. The emergence a…
View article: Development of New Live-Attenuated Vaccine Candidates Lacking Antibody-Dependent Enhancement (ADE) Against Dengue
Development of New Live-Attenuated Vaccine Candidates Lacking Antibody-Dependent Enhancement (ADE) Against Dengue Open
Dengue virus (DENV) threatens public health, especially in regions with tropical and subtropical climates. In 2024, the World Health Organisation reported 3.4 million confirmed dengue cases, with 16,000 severe cases and 3000 dengue-associa…
View article: Revolutionizing immunization: a comprehensive review of mRNA vaccine technology and applications
Revolutionizing immunization: a comprehensive review of mRNA vaccine technology and applications Open
Messenger RNA (mRNA) vaccines have emerged as a transformative platform in modern vaccinology. mRNA vaccine is a powerful alternative to traditional vaccines due to their high potency, safety, and efficacy, coupled with the ability for rap…
View article: Chimeric antigen receptor-natural killer cell therapy: current advancements and strategies to overcome challenges
Chimeric antigen receptor-natural killer cell therapy: current advancements and strategies to overcome challenges Open
Chimeric antigen receptor-natural killer (CAR-NK) cell therapy is a novel immunotherapy targeting cancer cells via the generation of chimeric antigen receptors on NK cells which recognize specific cancer antigens. CAR-NK cell therapy is ga…
View article: Isolation, Biological Characterization, and Quality Inspection of Human Umbilical Cord-derived Mesenchymal Stem Cells for Clinical Research
Isolation, Biological Characterization, and Quality Inspection of Human Umbilical Cord-derived Mesenchymal Stem Cells for Clinical Research Open
Background: Human umbilical cord mesenchymal stem cells (hUCMSCs) represent a valuable and versatile cell type derived from the umbilical cord tissue of newborns. These cells exhibit diverse characteristics, including multipotent different…
View article: A case series on safety and tolerability of human umbilical cord-derived mesenchymal stem cells on patients in Malaysia
A case series on safety and tolerability of human umbilical cord-derived mesenchymal stem cells on patients in Malaysia Open
Umbilical cord-derived mesenchymal stem cells for regenerative therapy are a promising treatment option for chronic illnesses. Umbilical cord-derived mesenchymal stem cells offer several advantages over other sources, which makes them an a…
View article: Synchronous Breast and Cervical Carcinoma: A Genetic Point of View
Synchronous Breast and Cervical Carcinoma: A Genetic Point of View Open
Breast carcinoma is the most common cancer of women in Malaysia. The most common sites of metastasis are the lung, liver, bone and brain. A 45-year-old lady was diagnosed with left invasive breast carcinoma stage IV (T4cN1M1) with axillary…