Seong Ho Bak
YOU?
Author Swipe
View article: Resveratrol from Peanut Sprout Extract Promotes NK Cell Activation and Antitumor Activity
Resveratrol from Peanut Sprout Extract Promotes NK Cell Activation and Antitumor Activity Open
Natural killer (NK) cells are innate immune cells that are crucial for anticancer activity and have been developed as an immune cell therapy for leukemia. However, their limited effectiveness against solid tumors has prompted research into…
View article: Deficiency of thioredoxin-interacting protein results in age-related thrombocytopenia due to megakaryocyte oxidative stress
Deficiency of thioredoxin-interacting protein results in age-related thrombocytopenia due to megakaryocyte oxidative stress Open
We provide evidence that the megakaryopoiesis pathway becomes exhausted with age in Txnip-/- mice with a decrease in terminal, mature MKs that response to thrombocytopenic challenge. Overall, this study demonstrates the role of TXNIP in me…
View article: Understanding NK cell biology for harnessing NK cell therapies: targeting cancer and beyond
Understanding NK cell biology for harnessing NK cell therapies: targeting cancer and beyond Open
Gene-engineered immune cell therapies have partially transformed cancer treatment, as exemplified by the use of chimeric antigen receptor (CAR)-T cells in certain hematologic malignancies. However, there are several limitations that need t…