Seonyang Park
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View article: Gene expression analysis of patients with chronic myeloid leukemia who discontinued tyrosine kinase inhibitor
Gene expression analysis of patients with chronic myeloid leukemia who discontinued tyrosine kinase inhibitor Open
The immunological mechanism of treatment-free remission is not clearly understood. We aimed to identify immune-related genetic differences that predict molecular relapse after tyrosine kinase inhibitor (TKI) discontinuation in patients wit…
View article: Back to basics: the coagulation pathway
Back to basics: the coagulation pathway Open
View article: P1556: EVALUATION OF THE USEFULNESS OF INTERFERON-GAMMA RELEASE ASSAY FOR THE DETECTION OF LATENT MYCOBACTERIUM TUBERCULOSIS INFECTIONS IN PATIENTS WHO UNDERWENT HEMATOPOIETIC STEM CELL TRANSPLANTATION
P1556: EVALUATION OF THE USEFULNESS OF INTERFERON-GAMMA RELEASE ASSAY FOR THE DETECTION OF LATENT MYCOBACTERIUM TUBERCULOSIS INFECTIONS IN PATIENTS WHO UNDERWENT HEMATOPOIETIC STEM CELL TRANSPLANTATION Open
Topic: 30. Infections in hematology (incl. supportive care/therapy) Background: Tuberculosis (TB) is still a major global public health problem. The likelihood of developing the active disease is much higher in frail patients, such as thos…
View article: Comparison of the effect of DLI according to cell sources in relapsed AML after allogeneic stem cell transplantation
Comparison of the effect of DLI according to cell sources in relapsed AML after allogeneic stem cell transplantation Open
For relapsed acute myeloid leukemia (AML) patients who received allogeneic hematopoietic stem cell transplantation, donor lymphocyte infusion (DLI) is an effective therapy. However, the cell source of DLI remains a topic of debate. In this…
View article: Effect of <i>BCR::ABL1</i> transcript type and droplet digital polymerase chain reaction on successful treatment-free remission in chronic myeloid leukemia patients who discontinued tyrosine kinase inhibitor
Effect of <i>BCR::ABL1</i> transcript type and droplet digital polymerase chain reaction on successful treatment-free remission in chronic myeloid leukemia patients who discontinued tyrosine kinase inhibitor Open
Background: Droplet digital polymerase chain reaction (ddPCR) is an exact method of measurement. Objectives: We conducted this study to identify the prognostic factors for successful treatment-free remission in patients with chronic-phase …
View article: The association of genetic alterations with response rate in newly diagnosed chronic myeloid leukemia patients
The association of genetic alterations with response rate in newly diagnosed chronic myeloid leukemia patients Open
View article: Ultra-deep sequencing mutation analysis of the BCR/ABL1 kinase domain in newly diagnosed chronic myeloid leukemia patients
Ultra-deep sequencing mutation analysis of the BCR/ABL1 kinase domain in newly diagnosed chronic myeloid leukemia patients Open
View article: Lenalidomide for anemia correction in lower-risk del(5q) myelodysplastic syndrome patients of Asian ethnicity
Lenalidomide for anemia correction in lower-risk del(5q) myelodysplastic syndrome patients of Asian ethnicity Open
Lenalidomide efficacy and tolerability were similar in the Asian del(5q) MDS patients and western patients. Dose reduction during treatment was common, but it was not associated with inferior outcomes.
View article: Use of Droplet Digital Polymerase Chain Reaction for Detecting Minimal Residual Disease: A Prospective Multi-Institutional Study
Use of Droplet Digital Polymerase Chain Reaction for Detecting Minimal Residual Disease: A Prospective Multi-Institutional Study Open
We found that ddPCR is a sensitive method for detecting MRD and that MRD could affect the duration of the treatment response.
View article: A phase 4 study of nilotinib in Korean patients with Philadelphia chromosome‐positive chronic myeloid leukemia in chronic phase: <scp>ENESTK</scp>orea
A phase 4 study of nilotinib in Korean patients with Philadelphia chromosome‐positive chronic myeloid leukemia in chronic phase: <span>ENESTK</span>orea Open
Although nilotinib has improved efficacy compared to imatinib, suboptimal response and intolerable adverse events ( AE s) limit its effectiveness in many patients with chronic myeloid leukemia in chronic phase ( CML ‐ CP ). We investigated…
View article: Salvage therapy for acute chemorefractory leukemia by allogeneic stem cell transplantation: the Korean experience
Salvage therapy for acute chemorefractory leukemia by allogeneic stem cell transplantation: the Korean experience Open
View article: Topical Recombinant Human Epidermal Growth Factor for Oral Mucositis Induced by Intensive Chemotherapy with Hematopoietic Stem Cell Transplantation: Final Analysis of a Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial
Topical Recombinant Human Epidermal Growth Factor for Oral Mucositis Induced by Intensive Chemotherapy with Hematopoietic Stem Cell Transplantation: Final Analysis of a Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial Open
The aim of this study was to evaluate the efficacy and safety of recombinant human epidermal growth factor (rhEGF) oral spray for oral mucositis (OM) induced by intensive chemotherapy with hematopoietic stem cell transplantation. In this p…
View article: Prognostic factors for re-mobilization using plerixafor and granulocyte colony-stimulating factor (G-CSF) in patients with malignant lymphoma or multiple myeloma previously failing mobilization with G-CSF with or without chemotherapy: the Korean multicenter retrospective study
Prognostic factors for re-mobilization using plerixafor and granulocyte colony-stimulating factor (G-CSF) in patients with malignant lymphoma or multiple myeloma previously failing mobilization with G-CSF with or without chemotherapy: the Korean multicenter retrospective study Open
View article: Psychometric analysis of the Korean version of the high-dose chemotherapy specific quality of life questionnaire module from the European Organization for Research and Treatment of Cancer (EORTC QLQ-HDC29)
Psychometric analysis of the Korean version of the high-dose chemotherapy specific quality of life questionnaire module from the European Organization for Research and Treatment of Cancer (EORTC QLQ-HDC29) Open
View article: Correlation between the Severity of Bone Pain and the Amount of CD34＋ Cells after Peripheral Blood Stem Cell Mobilization
Correlation between the Severity of Bone Pain and the Amount of CD34＋ Cells after Peripheral Blood Stem Cell Mobilization Open
Peripheral blood stem cells (PBSCs) are mobilized by granulocyte-colony stimulating factor (G-CSF), which causes several side effects in allogeneic donors. We report on side effects of G-CSF administration and determine which side effects …
View article: Long‐term follow‐up of imatinib plus combination chemotherapy in patients with newly diagnosed <scp>P</scp>hiladelphia chromosome‐positive acute lymphoblastic leukemia
Long‐term follow‐up of imatinib plus combination chemotherapy in patients with newly diagnosed <span>P</span>hiladelphia chromosome‐positive acute lymphoblastic leukemia Open
The effects of imatinib plus chemotherapy were assessed in 87 patients with newly diagnosed Philadelphia chromosome‐positive (Ph + ) acute lymphoblastic leukemia (ALL). Imatinib was administered continuously, starting from the eighth day o…
View article: Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia
Nilotinib combined with multiagent chemotherapy for newly diagnosed Philadelphia-positive acute lymphoblastic leukemia Open
Key Points Nilotinib plus multiagent chemotherapy was feasible and showed a comparable outcome to previous results with imatinib for Ph-pos ALL. The achievement of deep MR with nilotinib at postremission correlated well with the clinical o…
View article: Korean Guidelines for Treating Chronic Myelogenous Leukemia - The Korean Society of Hematology Chronic Myelogenous Leukemia Working Party
Korean Guidelines for Treating Chronic Myelogenous Leukemia - The Korean Society of Hematology Chronic Myelogenous Leukemia Working Party Open
목적: 만성골수성백혈병의 진단 및 치료를 위한 한국 치료 가이드라인은 한국 실정에 맞춘 내용을 통해 국내 치료방침 및 연구 기준을 표준화하기 위하여 제정되었다. 방법: 국내 만성골수성백혈병 전문가들을 대상으로 한 설문 조사와 자문 미팅을 거쳐 본 가이드라인을 작성하였다. 결과: 본 가이드라인에는 만성골수성백혈병의 진단 및 초기 검사, 예후인자, 만성기에서의 초치료 및 치료 중 확인 사항과 반응 평가, 이차 약제 변경 및 이후…