Seoung Chul Oh
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View article: Comparison of Homologous Recombination Repair Gene Next-Generation Sequencing Analysis in Patients With Metastatic Castration-Resistant Prostate Cancer Between Local and Central Laboratories in Korea
Comparison of Homologous Recombination Repair Gene Next-Generation Sequencing Analysis in Patients With Metastatic Castration-Resistant Prostate Cancer Between Local and Central Laboratories in Korea Open
The NGS approach at a local laboratory showed comparable analytical performance for identifying HRRm status to the FoundationOne CDx assay used at the central laboratory.
View article: Prediction of urine culture results by automated urinalysis with digital flow morphology analysis
Prediction of urine culture results by automated urinalysis with digital flow morphology analysis Open
To investigate the association between the results of urinalysis and those of concurrent urine cultures, and to construct a prediction model for the results of urine culture. A total of 42,713 patients were included in this study. Patients…
View article: An optimized<i>BRCA1/2</i>next-generation sequencing for different clinical sample types
An optimized<i>BRCA1/2</i>next-generation sequencing for different clinical sample types Open
On the comparison of the analytical performance according to different sample types, the buffy coat was not affected by sequencing artifacts and VAF shifted variants. Therefore, the blood test should be given priority in detecting germline…
View article: Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients
Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients Open
Recently, the Cancer Genome Atlas (TCGA) Research Network and Asian Cancer Research Group provided a new classification of gastric cancer (GC) to aid the development of biomarkers for targeted therapy and predict prognosis. We studied asso…
View article: Validation and optimization of the Ion Torrent S5 XL sequencer and Oncomine workflow for <i>BRCA1</i> and <i>BRCA2</i> genetic testing
Validation and optimization of the Ion Torrent S5 XL sequencer and Oncomine workflow for <i>BRCA1</i> and <i>BRCA2</i> genetic testing Open
In this study, we validated the analytical performance of BRCA1/2 sequencing using Ion Torrent's new bench-top sequencer with amplicon panel with optimized bioinformatics pipelines. Using 43 samples that were previously validated by Illumi…