Sung Yoon Lim
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View article: Effects of adjunctive dobutamine on outcomes among patients with septic shock: a propensity score matching analysis
Effects of adjunctive dobutamine on outcomes among patients with septic shock: a propensity score matching analysis Open
Background/Aims: Despite some evidence supporting its utility, the role of adjunctive dobutamine in the management of septic shock remains unclear.Methods: The nationwide prospective sepsis cohort of the Korean Sepsis Alliance was analyzed…
View article: Current status and future perspectives of minimally invasive liver surgery for hepatocellular carcinoma
Current status and future perspectives of minimally invasive liver surgery for hepatocellular carcinoma Open
The use of laparoscopic liver resection has rapidly increased. According to two international consensus meetings, certain resection methods are already considered standard procedures for liver resection, especially for small malignant tumo…
View article: Optimizing Extracorporeal Membrane Oxygenation Gas Exchange: Key Insights for Clinical Management
Optimizing Extracorporeal Membrane Oxygenation Gas Exchange: Key Insights for Clinical Management Open
This review examines the role of extracorporeal membrane oxygenation (ECMO) in the management of severe acute respiratory distress syndrome (ARDS), emphasizing its contribution to lung-protective ventilation through optimizing oxygenation …
View article: Optimal time and volume of fluid resuscitation in patients with sepsis: a nationwide multicenter cohort study
Optimal time and volume of fluid resuscitation in patients with sepsis: a nationwide multicenter cohort study Open
The optimal fluid resuscitation strategy for managing sepsis remains unknown. We aimed to examine the independent and joint associations of infusion time and volume of fluid resuscitation on mortality in patients with sepsis. We analyzed a…
View article: Enhancing LLMs' Clinical Reasoning with Real-World Data from a Nationwide Sepsis Registry
Enhancing LLMs' Clinical Reasoning with Real-World Data from a Nationwide Sepsis Registry Open
Although large language models (LLMs) have demonstrated impressive reasoning capabilities across general domains, their effectiveness in real-world clinical practice remains limited. This is likely due to their insufficient exposure to rea…
View article: Determinants of Limiting Life-Sustaining Treatment in Critically Ill COVID-19 Patients: A Multicenter Study in Korean Intensive Care Units
Determinants of Limiting Life-Sustaining Treatment in Critically Ill COVID-19 Patients: A Multicenter Study in Korean Intensive Care Units Open
Background: Understanding of the life-sustaining treatment (LST) decisions in critically ill coronavirus disease 2019 (COVID-19) patients remains limited. This study aimed to identify factors influencing LST decisions, and compare clinical…
View article: Epidemiology and risk factors of fungal pathogens in sepsis: a prospective nationwide multicenter cohort study
Epidemiology and risk factors of fungal pathogens in sepsis: a prospective nationwide multicenter cohort study Open
View article: Efficacy of Portable Ultrasonography for Early Detection of Pneumothorax Following Lung Biopsy
Efficacy of Portable Ultrasonography for Early Detection of Pneumothorax Following Lung Biopsy Open
Background: Pneumothorax is a notable complication of lung biopsy, and its early detection is crucial. This study aimed to compare the sensitivities of handheld portable lung ultrasonography and chest radiography in identifying early pneum…
View article: A Prospective, Multicenter, Randomized, Noninferiority Trial of Stopad® Versus Tachosil® for Hemostasis After Liver Resection
A Prospective, Multicenter, Randomized, Noninferiority Trial of Stopad® Versus Tachosil® for Hemostasis After Liver Resection Open
Background: Hemostatic products are widely used to control bleeding in hepatic resections. Stopad is a pad-type hemostatic agent containing carboxymethyl chitosan and recombinant thrombin-like hemocoagulase. Methods: We conducted a prospec…
View article: Resident and nurse attitudes toward a rapid response team in a tertiary hospital in South Korea
Resident and nurse attitudes toward a rapid response team in a tertiary hospital in South Korea Open
Background: Residents and nurses who activate rapid response teams (RRTs) are well positioned to offer insights on its effectiveness. Here, we assess such evaluation of RRTs and identify barriers to activation in a 1,400-bed teaching hospi…
View article: Evolution of Liver Resection for Hepatocellular Carcinoma: Change Point Analysis of Textbook Outcome over Twenty Years
Evolution of Liver Resection for Hepatocellular Carcinoma: Change Point Analysis of Textbook Outcome over Twenty Years Open
Background and Objectives: The aim of this study was to comprehensively analyze the evolution in textbook outcome (TO) achievement after liver resection for hepatocellular carcinoma (HCC) over two decades at a single tertiary referral cent…
View article: Influence of underlying condition and performance of sepsis bundle in very old patients with sepsis: a nationwide cohort study
Influence of underlying condition and performance of sepsis bundle in very old patients with sepsis: a nationwide cohort study Open
Background Sepsis is a life-threatening condition that affects individuals of all ages; however, it presents unique challenges in very old patients due to their complex medical histories and potentially compromised immune systems. This stu…
View article: Culture-negative sepsis may be a different entity from culture-positive sepsis: a prospective nationwide multicenter cohort study
Culture-negative sepsis may be a different entity from culture-positive sepsis: a prospective nationwide multicenter cohort study Open
View article: Etiology and Clinical Prediction of Community-Acquired Lower Respiratory Tract Infection in Children
Etiology and Clinical Prediction of Community-Acquired Lower Respiratory Tract Infection in Children Open
In children with LRTI, various factors associated with viral or bacterial/M. pneumoniae infections were identified, which may serve as guidance for antibiotic prescription.
View article: Application of metabolic phase-specific modified nutrition risk in critically ill score: a prospective observational study in critically ill patients
Application of metabolic phase-specific modified nutrition risk in critically ill score: a prospective observational study in critically ill patients Open
Background and aims The prevalence of malnutrition in intensive care units (ICU) is high and can be caused by poor intake or absorption of nutrients in the digestive track, as well as disease-related inflammation. As strong catabolism rest…
View article: Comparison of the risk of pneumothorax in COVID-19 and seasonal influenza
Comparison of the risk of pneumothorax in COVID-19 and seasonal influenza Open
Limited evidence exists regarding the link between coronavirus disease 2019 (COVID-19) and pneumothorax. Therefore, we aimed to evaluate the occurrence rate of pneumothorax in hospitalized patients with COVID-19 and compare the risk of pne…
View article: Association of baseline muscle mass with functional outcomes in intensive care unit survivors: A single-center retrospective cohort study in Korea
Association of baseline muscle mass with functional outcomes in intensive care unit survivors: A single-center retrospective cohort study in Korea Open
In critical care settings, ultrasound (US) of the quadriceps muscle and Bioelectrical Impedance Analysis (BIA) are noninvasive and widely available tools to evaluate muscle mass. We studied whether baseline muscle mass affects physical fun…
View article: Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments
Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments Open
Importance Early detection and management of sepsis are crucial for patient survival. Emergency departments (EDs) play a key role in sepsis management but face challenges in timely response due to high patient volumes. Sepsis alert systems…
View article: Clinical Efficacy and Safety of an Automatic Closed-Suction System in Mechanically Ventilated Patients with Pneumonia: A Multicenter, Prospective, Randomized, Non-Inferiority, Investigator-Initiated Trial
Clinical Efficacy and Safety of an Automatic Closed-Suction System in Mechanically Ventilated Patients with Pneumonia: A Multicenter, Prospective, Randomized, Non-Inferiority, Investigator-Initiated Trial Open
Endotracheal suctioning is an essential but labor-intensive procedure, with the risk of serious complications. A brand new automatic closed-suction device was developed to alleviate the workload of healthcare providers and minimize those c…
View article: Shock indices are associated with in-hospital mortality among patients with septic shock and normal left ventricular ejection fraction
Shock indices are associated with in-hospital mortality among patients with septic shock and normal left ventricular ejection fraction Open
Background The understanding of shock indices in patients with septic shock is limited, and their values may vary depending on cardiac function. Methods This prospective cohort study was conducted across 20 university-affiliated hospitals …
View article: Polymicrobial bloodstream infections per se do not increase mortality compared to monomicrobial bloodstream infections in sepsis patients: a Korean nationwide sepsis cohort study
Polymicrobial bloodstream infections per se do not increase mortality compared to monomicrobial bloodstream infections in sepsis patients: a Korean nationwide sepsis cohort study Open
View article: Factors related to lung function outcomes in critically ill COVID-19 patients in South Korea
Factors related to lung function outcomes in critically ill COVID-19 patients in South Korea Open
Background: New variants of the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic continue to emerge. However, little is known about the effect of these variants on clinical outcomes. This study evaluated the risk fact…
View article: Correction: Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study
Correction: Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study Open
View article: Early Sepsis-Associated Acute Kidney Injury and Obesity
Early Sepsis-Associated Acute Kidney Injury and Obesity Open
Importance The prevalence of obesity is increasing in the intensive care unit (ICU). Although obesity is a known risk factor for chronic kidney disease, its association with early sepsis-associated acute kidney injury (SA-AKI) and their co…
View article: Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study
Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study Open
View article: Epidemiology of Sepsis-Associated Acute Kidney Injury in Critically Ill Patients: A Multicenter, Prospective, Observational Cohort Study
Epidemiology of Sepsis-Associated Acute Kidney Injury in Critically Ill Patients: A Multicenter, Prospective, Observational Cohort Study Open
View article: Risk Factors for the Mortality of Patients With Coronavirus Disease 2019 Requiring Extracorporeal Membrane Oxygenation in a Non-Centralized Setting: A Nationwide Study
Risk Factors for the Mortality of Patients With Coronavirus Disease 2019 Requiring Extracorporeal Membrane Oxygenation in a Non-Centralized Setting: A Nationwide Study Open
Older age and receipt of CRRT were associated with higher mortality rates among patients with COVID-19 who received ECMO.
View article: Evaluation of the Current Urgency-Based Lung Allocation System in Korea with Simulation of the Eurotransplant Lung Allocation Score
Evaluation of the Current Urgency-Based Lung Allocation System in Korea with Simulation of the Eurotransplant Lung Allocation Score Open
Simulation of the ET-LAS with KOTRY data showed that the Korean urgency definition may not allocate lungs by urgency, especially for patients in non-status 0; therefore, it needs to be revised.
View article: Clinical effects of bacteremia in sepsis patients with community-acquired pneumonia
Clinical effects of bacteremia in sepsis patients with community-acquired pneumonia Open
View article: Supervised machine learning model to predict mortality in patients undergoing venovenous extracorporeal membrane oxygenation from a nationwide multicentre registry
Supervised machine learning model to predict mortality in patients undergoing venovenous extracorporeal membrane oxygenation from a nationwide multicentre registry Open
Background Existing models have performed poorly when predicting mortality for patients undergoing venovenous extracorporeal membrane oxygenation (VV-ECMO). This study aimed to develop and validate a machine learning (ML)-based prediction …