Explanipedia

Factors associated with failed epidural blood patch after accidental dural puncture in obstetrics: a prospective, multicentre, international cohort study Open

Anil Gupta, Marc Van de Velde, Anders Magnuson, Christian von Heymann, E. Guasch , et al. · 2022

Developing a supervised machine learning model for predicting perioperative acute kidney injury in arthroplasty patients Open

Okke Nikkinen, Timo Kolehmainen, Toni Aaltonen, Elias Jämsä, Seppo Alahuhta , et al. · 2022

The performance of the models improved after the inclusion of intra- and postoperative features with preoperative features. The results of our study are not generalizable, and additional larger studies are needed. The optimal ML method for…

Procedural Sedation Intubation in a Paramedic-Staffed Helicopter Emergency Medical System in Northern Finland Open

Sami Länkimäki, Michael Spalding, Antti Saari, Seppo Alahuhta · 2021

Difference in postoperative opioid consumption after spinal versus general anaesthesia for ankle fracture surgery—A retrospective cohort study Open

Pasi Lehto, Merja Vakkala, Seppo Alahuhta, Janne Liisanantti, Tero Kortekangas , et al. · 2021

Background Surgical treatment of ankle fracture is associated with significant pain and high postoperative opioid consumption. The anaesthesia method may affect early postoperative pain. The main objective of the study was to compare posto…

Perioperative acute kidney injury and urine output in lower limb arthroplasties Open

Okke Nikkinen, Elias Jämsä, Toni Aaltonen, Seppo Alahuhta, Pasi Ohtonen , et al. · 2021

Background This study aimed to evaluate the occurrence and perioperative risk factors of acute kidney injury (AKI) in primary elective hip and knee and emergency hip arthroplasty patients. We also aimed to assess the effect of urine output…

Single dose epidural hydromorphone in labour pain: maternal pharmacokinetics and neonatal exposure Open

Terhi Puhto, Merja Kokki, Henriikka Hakomäki, Michael Spalding, Teemu Gunnar , et al. · 2020

Introduction Epidural hydromorphone could be useful in obstetric analgesia as there is a need for a more water-soluble opioid than sufentanil or fentanyl with prolonged analgesic effect. To our knowledge, the pharmacokinetics of epidural h…

Yhtenäiset vaatimukset lääketieteen ja hammaslääketieteen tohtorintutkinnolle Suomessa Open

Petri Lehenkari, Timo Tuovinen, Seppo Alahuhta, Mika Rämet, Seppo Parkkila · 2020

Corrigendum to: Reducing risk of spinal haematoma from spinal and epidural pain procedures Open

Harald Breivik, Hilde M. Norum, Christian Fenger‐Eriksen, Seppo Alahuhta, G. Vigfusson , et al. · 2019

Case Report: Chemotherapy in Conjunction With Blood–Brain Barrier Disruption for a Patient With Germ Cell Tumor With Multiple Brain Metastases Open

Oula Knuutinen, Hanne Kuitunen, Seppo Alahuhta, Juha‐Matti Isokangas, Eila Sonkajärvi , et al. · 2018

Reducing risk of spinal haematoma from spinal and epidural pain procedures Open

Harald Breivik, Hilde M. Norum, Christian Fenger‐Eriksen, Seppo Alahuhta, G. Vigfusson , et al. · 2018

Background and aims: Central neuraxial blocks (CNB: epidural, spinal and their combinations) and other spinal pain procedures can cause serious harm to the spinal cord in patients on antihaemostatic drugs or who have other risk-factors for…

Incidence and predictive factors of spinal cord stimulation treatment after lumbar spine surgery Open

Merja Vakkala, Voitto Järvimäki, Hannu Kautiainen, Maija Haanpää, Seppo Alahuhta · 2017

In our region, the SCS treatment is used only for very serious pain conditions. Waiting time is too long and it may be the reason why this treatment option is not offered to all candidates.

Real-time monitoring of human blood-brain barrier disruption Open

Vesa Kiviniemi, Vesa Korhonen, Jukka Kortelainen, Seppo Rytky, Tuija Keinänen , et al. · 2017

Chemotherapy aided by opening of the blood-brain barrier with intra-arterial infusion of hyperosmolar mannitol improves the outcome in primary central nervous system lymphoma. Proper opening of the blood-brain barrier is crucial for the tr…

Depressive symptoms are associated with poor outcome for lumbar spine surgery Open

Voitto Järvimäki, Hannu Kautiainen, Maija Haanpää, Hannu Koponen, Michael Spalding , et al. · 2016

Background and aims The symptoms of pain and depression often present concomitantly, but little is known as to how the different subtypes of depression affect surgical outcome. The aim of this study was to determine whether there is a diff…

Fatal injuries in rural and urban areas in northern Finland: a 5‐year retrospective study Open

Lasse Raatiniemi, Tine Steinvik, Janne Liisanantti, Pasi Ohtonen, Matti Martikainen , et al. · 2016

Background Finland has the fourth highest injury mortality rate in the European Union. To better understand the causes of the high injury rate, and prevent these fatal injuries, studies are needed. Therefore, we set out to complete an anal…

Respiratory Effort Belts in Postoperative Respiratory Monitoring: Pilot Study with Different Patients Open

Tiina M. Seppänen, Olli‐Pekka Alho, Merja Vakkala, Seppo Alahuhta, Tapio Seppänen · 2016

Respiratory complications are common in patients after the general anaesthesia. Respiratory depression often occurs in association with postoperative opioid analgesia. Currently, there is a need for a continuous non-invasive respiratory mo…

Short-term outcome and differences between rural and urban trauma patients treated by mobile intensive care units in Northern Finland: a retrospective analysis Open

Lasse Raatiniemi, Janne Liisanantti, Suvi Niemi, Heini Nal, Pasi Ohtonen , et al. · 2015

Feasibility of LMA Supreme for airway management in unconscious patients by ALS paramedics Open

Sami Länkimäki, Seppo Alahuhta, Tom Silfvast, Jouni Kurola · 2015

We conclude that the LMA-S seems to be relatively easy and quick to insert in unconscious patients by paramedics. However, we found out that there were ventilation related problems with the LMA-S. Further studies are warranted.

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