Serdal Uğurlu
YOU?
Author Swipe
Familial Mediterranean Fever: A Comprehensive Review of Pathogenesis, Genetics, and Epigenetic Regulation Open
Familial Mediterranean Fever (FMF) is the first described and most prevalent monogenic autoinflammatory periodic fever syndrome worldwide. The disease is caused by pathogenic variants in the MEFV (Mediterranean fever) gene, which lead to d…
Perinatal Outcomes in Women Exposed to Monoclonal Antibody Biologics During Pregnancy Open
Objective: Biologics, often known as monoclonal antibody biologics (mAbs), have improved the treatment and quality of life for many patients with inflammatory and autoimmune diseases. Disease remission is the strongest predictor of perinat…
Central nervous system involvement and mimickers in ANCA associated vasculitis Open
Objective Central nervous system (CNS) involvement is rare in ANCA-associated vasculitis (AAV). On the other hand, AAV patients may develop complications or other conditions that mimic CNS involvement. We aimed to present the clinical, lab…
Rituximab Treatment in Lupus Nephritis Resistant to Conventional Therapy: A Single-Centre Experience Open
Rituximab significantly improved disease activity in lupus nephritis patients, reducing proteinuria, SLEDAI-2K scores, and allowing for steroid dose reduction. Given its efficacy and safety, rituximab may be a promising option for patients…
A RETROSPECTIVE STUDY ON LUPUS NEPHRITIS: EXAMINING CLINICAL, SEROLOGICAL, AND PROGNOSTIC DIFFERENCES BETWEEN PEDIATRIC AND ADULT-ONSET PATIENTS IN A TERTIARY MEDICAL CENTER Open
PT008 / #89 Topic: AS15 - Lupus Nephritis-Clinical POSTER TOUR 02: RECENT INSIGHTS ON THE PATHOGENESIS OF LUPUS NEPHRITIS 23-05-2025 10:00 AM - 10:40 AM Background/Purpose Renal involvement occurs in about 40-50% of adult SLE patients. Ped…
Emerging treatment approaches for VEXAS syndrome: a systematic review and meta-analysis Open
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a monogenic autoinflammatory disorder with significant morbidity and mortality. Numerous treatment options including azacitidine, JAK inhibitors, IL-6 inhibitors,…
Two cases of dermatomyositis with anti-cN1A antibody positivity Open
Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of autoimmune-mediated disorders. One of the most important developments in recent years regarding IIMs is the clinical use of myositis-specific antibodies and myositis-as…
Fertility in male patients with familial Mediterranean fever and paternal effect of FMF on pregnancy outcomes and complications Open
Objectives This study investigates the impact of Familial Mediterranean Fever (FMF) and its treatment on male infertility, and the paternal effect of FMF on pregnancy outcomes or complications. Methods We enrolled 282 adult male FMF patien…
Fertility, pregnancy outcomes, and disease activity during pregnancy in patients with juvenile idiopathic arthritis: a descriptive study Open
To investigate the fertility status, pregnancy outcomes, and disease activity during and after pregnancy in patients with juvenile idiopathic arthritis (JIA) currently being followed up at an adult rheumatology clinic. This study included …
Mimics and challenging presentations of DADA2 Open
Deficiency of adenosine deaminase 2 (DADA2) has been a challenging diagnosis to make since it was first described in 2014. The disease represents a wide range of phenotypes. Therefore, it may present with various clinical patterns. Through…
View article: Prevalence, incidence and geographic distribution of familial Mediterranean fever in Turkey: a national cohort study
Prevalence, incidence and geographic distribution of familial Mediterranean fever in Turkey: a national cohort study Open
FMF is beyond the definition of a rare disease and a significant health issue in Turkey, with a non-uniform distribution influenced by both genetic and historical factors. The findings of this study highlight the utility of national electr…
Measuring Transition Readiness of Patients After Transfer from Pediatric to Adult Care in Rheumatology Open
Transitional care is essential to maintain the continuity of care in younger patients with rheumatic diseases. In this study, we aimed to assess the transition readiness of rheumatology patients who had already transferred from pediatric t…
Novel use of interleukin-1 antagonists in male familial Mediterranean fever patients with infertility: Case series Open
Familial Mediterranean fever (FMF) is primarily treated with colchicine. For colchicine-resistant cases, interleukin (IL)-1 antagonists, such as anakinra and canakinumab, are used.[1] Male infertility, a rare FMF complication, is often att…
Characteristics of arthritis in patients with familial <span>Mediterranean</span> fever Open
Background Many of the familial Mediterranean fever (FMF) patients present with arthritis during attacks, which may vary in its characteristics. Aims In this study, we aimed to describe and characterise arthritis in FMF patients. Methods W…
View article: Relationship of psoriatic arthritis with nail and scalp involvement in Turkish psoriasis patients: Multicentered cross-sectional study
Relationship of psoriatic arthritis with nail and scalp involvement in Turkish psoriasis patients: Multicentered cross-sectional study Open
Psoriasis is a common multisystem inflammatory disease, and arthritis is an essential component of the disorder, requiring early diagnosis and prompt treatment for successful management. In this study, we aimed to investigate the relations…
Exploring S100A8/A9, neopterin, and MMP3 in familial Mediterranean fever Open
Familial Mediterranean fever (FMF) is characterized by inflammatory attacks due to overactivation of pyrin inflammasome. This study aimed to investigate the reliability of S100A8/A9, neopterin, and matrix metalloproteinase 3 (MMP3) at moni…
Efficacy and safety of biologic drugs in Still's disease: a systematic review and network meta-analysis of randomized controlled trials Open
Objectives Still’s disease is a rare autoinflammatory disorder characterized by systemic inflammation, fever, rash and arthritis. The term ‘Still’s disease’ covers the paediatric subtype systemic juvenile idiopathic arthritis (sJIA) and ad…
Unusual Clinical Presentation of Sarcoidosis with Thrombocytopenia, Bone Marrow Involvement, and Myocardial Infiltration: A Case Report Open
This case study describes a 67-year-old female patient who presented with shortness of breath and quick exhaustion. In 2018, initial symptoms led to a diagnostic thoracic CT scan, which confirmed sarcoidosis using endobronchial ultrasound …
Secukinumab after first-line tumor necrosis factor-alpha inhibitor therapy in psoriatic arthritis: A real-world retrospective cohort study Open
Objectives: This study compared the secukinumab treatment responses and adverse effects in psoriatic arthritis patients who received secukinumab as second-line with those that received secukinumab after two or more tumor necrosis factor-al…
Anakinra in the Management of Adult-Onset Still’s Disease: A Single-Center Experience Open
Objectives Adult-onset Still’s disease (AOSD) is a rare systemic autoinflammatory disorder of unknown etiology characterized by systemic inflammation, high fever, salmon-colored skin rash, arthralgia, and arthritis. Patients with AOSD may …
P74 Late-onset monogenic lupus: a case-based review Open
Objective To highlight Mendelian inheritance in adult-onset systemic lupus erythematosus with a unique case of spondyloenchondrodysplasia-immune dysregulation and explore the potential of baricitinib as a promising treatment. Methods We pr…
P86 Rituximab therapy in lupus nephritis resistant to conventional therapy – A single center experience (case series) Open
Objective Lupus nephritis (LN) is challenging, especially in treatment-resistant cases. This retrospective study evaluates rituximab's effectiveness in LN patients at our clinic. Methods We retrospectively analyzed LN patients who received…