Sara Coppola
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View article: Enhancing the Performance of Planar SERS Sensors with Pyroelectrohydrodynamic Jet Printing
Enhancing the Performance of Planar SERS Sensors with Pyroelectrohydrodynamic Jet Printing Open
An alternative method for fabricating planar surface-enhanced Raman spectroscopy (SERS) sensors, offering enhanced performance compared to conventional drop-casting techniques, is presented. We synthesized stable gold nanoparticles (AuNPs)…
View article: Highly sensitive detection of different aggregation stages of Aβ1-42 -amyloid peptide in urine-like samples by auto-fluorescence
Highly sensitive detection of different aggregation stages of Aβ1-42 -amyloid peptide in urine-like samples by auto-fluorescence Open
Several studies demonstrated that the fibrillation process of β-amyloid peptides, including Aβ1-42, can be toxic at different stages. Such process is involved in the formation of plaques in the brains of patients affected by neurodegenerat…
View article: Indirect Impact of Pandemic on the Diagnosis of New Primary Melanoma: A Retrospective, Multicenter Study
Indirect Impact of Pandemic on the Diagnosis of New Primary Melanoma: A Retrospective, Multicenter Study Open
Background/Objectives: The indirect impact of the pandemic on the diagnosis and treatment of new primary melanoma has been carefully evaluated in recent years. The aim of the present study was to investigate if the indirect impact of the p…
View article: The pathologic and genomic evolution of primary malignant phyllodes tumors of the breast: retrospective cohort study and case-control genomic analysis
The pathologic and genomic evolution of primary malignant phyllodes tumors of the breast: retrospective cohort study and case-control genomic analysis Open
Background In patients with phyllodes tumors of the breast, the presence of mediator of RNA polymerase II transcription subunit 12 homolog mutations (MED12m) and a history of previous fibroadenoma may predict better outcomes. To aid in the…
View article: A Deep Learning-Based Probabilistic Approach for Non-Destructive Testing of Aircraft Components Using Laser Ultrasonic Data
A Deep Learning-Based Probabilistic Approach for Non-Destructive Testing of Aircraft Components Using Laser Ultrasonic Data Open
Composite structures are commonly used in complex applications such as automotive and aerospace due to their high strength-to-weight ratio. Although strictly supervised and inspected, they are often subject to dynamic events during their u…
View article: Thin free-standing liquid films manipulation: device design to turn on/off gravity in flow regimes for thickness map control and for material structuring
Thin free-standing liquid films manipulation: device design to turn on/off gravity in flow regimes for thickness map control and for material structuring Open
We design a device to control liquid film drainage, able to switch between viscous-capillary and viscous-gravity regimes to stabilize thickness and modify particle arrangement, offering potential for film studies and 2D structure fabricati…
View article: Sensitive colorimetric immunosensor using AuNP-functionalized polymer film for picogram-level detection of Tau protein intermediate aggregates
Sensitive colorimetric immunosensor using AuNP-functionalized polymer film for picogram-level detection of Tau protein intermediate aggregates Open
Here we demonstrate for the first time that an antibody-gold nanoparticles (AuNPs)-polymer conjugate thin-film biosensor can easily be fabricated to selectively capture Tau protein. Gold nanoparticles (AuNPs) are employed as sensing elemen…
View article: Thermo-Optical Modulation of PPLN Crystal for Tunable Poisson Spot Array
Thermo-Optical Modulation of PPLN Crystal for Tunable Poisson Spot Array Open
Lithium Niobate is a ferroelectric material with interesting physical properties. In particular, Periodically Poled Lithium Niobate (PPLN) crystals have been used in diverse applications, such as non-linear optics or microlens array fabric…
View article: Non-destructive evaluation and Structural Health Monitoring of impact induced damage in composite structures using ultrasonic approaches and shearography
Non-destructive evaluation and Structural Health Monitoring of impact induced damage in composite structures using ultrasonic approaches and shearography Open
Composite structures are massively used thanks to the high strength-to-weight ratio, making them ideal for lightweight and durable structures in aviation. However, Impact may arise at any time during lifetime on composite aerostructures an…
View article: Dynamic wire-pull rubber diaphragm for rapid formation and spatio-temporal investigation of multi-shape free-standing liquid films
Dynamic wire-pull rubber diaphragm for rapid formation and spatio-temporal investigation of multi-shape free-standing liquid films Open
Quantitative manufacturing and characterization of thin films are relevant in different scientific and industrial fields. Especially, for the studies of fluid dynamics, the experimental verification of theoretical models creates the need o…
View article: Self-assembling of PDMS microlens arrays through pyro-EHD for real-time 3D microscopy
Self-assembling of PDMS microlens arrays through pyro-EHD for real-time 3D microscopy Open
The electrohydrodynamic effect has been exploited for the fabrication of polymeric microlenses through different approaches. Here we show that microlens arrays obtained with the pyro-EHD self-assembling process exhibit high fill-factor and…
View article: 101P Primary malignant phyllodes tumors of the breast: A retrospective analysis from a referral center
101P Primary malignant phyllodes tumors of the breast: A retrospective analysis from a referral center Open
The treatment of primary malignant phyllodes tumors of the breast (B-MPT) consists of wide local excision with negative margins (≥1 cm). However, because of their rarity, prognostic factors, optimal type of surgery and adjuvant treatments …
View article: Highly sensitive detection of a neurodegenerative protein biomarker by using the pyro-electrohydrodynamic jet
Highly sensitive detection of a neurodegenerative protein biomarker by using the pyro-electrohydrodynamic jet Open
A set of protein biomarkers are largely recognized as responsible of neurodegeneration mechanisms and hence as potential targets to be detected in low abundant concentrations in body fluids for performing early diagnosis. As an example, th…
View article: Exploring the Frontiers of Non-Destructive Techniques: Shearography, Ultrasound Laser and Thermography
Exploring the Frontiers of Non-Destructive Techniques: Shearography, Ultrasound Laser and Thermography Open
Non-destructive testing (NDT) techniques serve as indispensable tools across diverse industries, facilitating material and component inspection without inflicting damage. This article underscores the paramount importance of NDT methods in …
View article: Robot-assisted Inguinal Lymphadenectomy: Evolution of the technique with the Alexis® Wound Protector/Retractor
Robot-assisted Inguinal Lymphadenectomy: Evolution of the technique with the Alexis® Wound Protector/Retractor Open
Introduction: Robot-assisted inguinal lymphadenectomy (RAIL) has been described as a reliable alternative to traditional open surgery. We reported the evolution of our technique for RAIL after introducing the Alexis® wound protector/retrac…
View article: Miniaturized, high numerical aperture confocal fluorescence detection enhanced with pyroelectric droplet accumulation for sub-attomole analyte diagnosis
Miniaturized, high numerical aperture confocal fluorescence detection enhanced with pyroelectric droplet accumulation for sub-attomole analyte diagnosis Open
To meet the growing demand for early fatal disease screening among large populations, current fluorescence detection instruments aiming at point-of-care diagnosis have the tendency to be low cost and high sensitivity, with a high potential…
View article: A narrative review of minimally invasive techniques for treatment of gastric gastrointestinal stromal tumors
A narrative review of minimally invasive techniques for treatment of gastric gastrointestinal stromal tumors Open
Background and Objective: Minimally invasive approach for small gastric gastrointestinal stromal tumors (GISTs) (<5 cm) is widely accepted according to National Comprehensive Cancer Network (NCCN) and European Society for Medical Oncology …
View article: On-the-Fly Formation of Polymer Film at Water Surface
On-the-Fly Formation of Polymer Film at Water Surface Open
The self-propulsion of bodies floating in water is of great interest for developing new robotic and intelligent systems at different scales, and whenever possible, Marangoni propulsion is an attractive candidate for the locomotion of untet…
View article: Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists
Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists Open
During the coronavirus disease 19 (COVID-19) pandemic, extracorporeal membrane oxygenation (ECMO) has been proposed as a possible therapy for COVID-19 patients with acute respiratory distress syndrome. This pictorial review is intended to …
View article: Instant <i>in situ</i> formation of a polymer film at the water–oil interface
Instant <i>in situ</i> formation of a polymer film at the water–oil interface Open
A completely new method for easy and quick formation of a thin polymer film at the special setting of a stratified oil/water interface. Morphological SEM and quantitative full-field characterization have been reported using digital hologra…
View article: Digital holography as metrology tool at micro-nanoscale for soft matter
Digital holography as metrology tool at micro-nanoscale for soft matter Open
The appearance of the first laser approximately 12 years after the invention of holography by Gabor (1948) revolutionized the field of optical metrology. In fact, the invention of holographic interferometry enabled the exploitation of inte…
View article: Droplet Ejection and Liquid Jetting by Visible Laser Irradiation in Pyro‐Photovoltaic Fe‐Doped LiNbO<sub>3</sub> Platforms
Droplet Ejection and Liquid Jetting by Visible Laser Irradiation in Pyro‐Photovoltaic Fe‐Doped LiNbO<sub>3</sub> Platforms Open
Controlling liquid dispensing and jetting from a reservoir drop or a liquid film require strong electric fields. One efficient method proposed some years ago is based on the high pyroelectric‐electrohydrodynamic (EHD) effect presented by l…
View article: SensApp: a FET-Open project for developing a supersensor able to detect Alzheimer's disease biomarkers in blood
SensApp: a FET-Open project for developing a supersensor able to detect Alzheimer's disease biomarkers in blood Open
The goal of the SensApp FET-Open project is to develop an innovative super-sensor that will be able to detect Alzheimer’s disease (AD) biomarkers (β-amyloid, Tau and pTAU) in peripheral blood. Considering that nowadays an accurate diagnosi…
View article: SensApp_Deliverbale_D1.7_International Symposium
SensApp_Deliverbale_D1.7_International Symposium Open
Inrernational Symposium
View article: Intelligent polymer droplets eject membranes and drive multimodal-propulsion of floating objects
Intelligent polymer droplets eject membranes and drive multimodal-propulsion of floating objects Open
Self-propulsion of bodies floating in water is of great interest for developing new robotic and intelligent systems at different scales. Frequently, the propulsion concept has been related to the Marangoni effect often demonstrated through…