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View article: Potential risks of a non-matched vegan diet on biomarkers of health status, body composition and performance in young female athletes – a 12-week randomized controlled trial
Potential risks of a non-matched vegan diet on biomarkers of health status, body composition and performance in young female athletes – a 12-week randomized controlled trial Open
Background A vegan diet is frequently associated with a health-conscious lifestyle and has become increasingly adopted by athletes. However, empirical evidence regarding its impact on athletic performance and health—particularly in young f…
View article: Sportizumab – Multimodal progressive exercise over 10 weeks decreases Th17 frequency and CD49d expression on CD8+ T cells in relapsing-remitting multiple sclerosis: A randomized controlled trial
Sportizumab – Multimodal progressive exercise over 10 weeks decreases Th17 frequency and CD49d expression on CD8+ T cells in relapsing-remitting multiple sclerosis: A randomized controlled trial Open
The 10-week multimodal exercise intervention mainly affected circulating T cells harboring a pathophysiological phenotype in MS. The findings of a decreased frequency of pathogenic Th17 cells and the reduced CNS-homing potential of CD8+ T …
View article: Acute exercise activates the AHR in peripheral blood mononuclear cells in an intensity-dependent manner
Acute exercise activates the AHR in peripheral blood mononuclear cells in an intensity-dependent manner Open
The findings of this study show that acute endurance exercise activates a receptor that has been described to integrate metabolic signals into the immune system. We uncover a potential mechanistic link on how exercise modulates the immune …
View article: Kinetics of Immune Cell Mobilization during Acute Aerobic Exercise in Healthy Adults
Kinetics of Immune Cell Mobilization during Acute Aerobic Exercise in Healthy Adults Open
While pre-post differences in immune cell mobilization after acute aerobic exercise are well investigated, less is known about when and to what extent immune cells are mobilized during acute aerobic exercise. This experimental trial aimed …
View article: Acute exercise increases systemic kynurenine pathway metabolites and activates the AHR in human PBMCs
Acute exercise increases systemic kynurenine pathway metabolites and activates the AHR in human PBMCs Open
The kynurenine pathway of tryptophan degradation generates several metabolites such as kynurenine or kynurenic acid that serve as endogenous ligands of the aryl hydrocarbon receptor (AHR). Due to its distinct biological roles particularly …
View article: Tissue‐specific effects of exercise as <scp>NAD</scp><sup>+</sup>‐boosting strategy: Current knowledge and future perspectives
Tissue‐specific effects of exercise as <span>NAD</span><sup>+</sup>‐boosting strategy: Current knowledge and future perspectives Open
Nicotinamide adenine dinucleotide (NAD + ) is an evolutionarily highly conserved coenzyme with multi‐faceted cell functions, including energy metabolism, molecular signaling processes, epigenetic regulation, and DNA repair. Since the disco…
View article: Distinct distribution patterns of exercise-induced natural killer cell mobilization into the circulation and tumor tissue of patients with prostate cancer
Distinct distribution patterns of exercise-induced natural killer cell mobilization into the circulation and tumor tissue of patients with prostate cancer Open
The mobilization and activation of natural killer (NK) cells have been proposed as key mechanisms promoting anti-oncogenic effects of physical exercise. Although mouse models have proven that physical exercise recruits NK cells to tumor ti…
View article: Acute exercise induces natural killer cell mobilization but not infiltration into prostate cancer tissue in humans
Acute exercise induces natural killer cell mobilization but not infiltration into prostate cancer tissue in humans Open
The mobilization and activation of natural killer (NK) cells have been proposed as key mechanisms promoting anti oncogenic effects of physical exercise. Although mouse models have proven that physical exercise recruits NK cells to tumor ti…