Sergio Di Nuzzo
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View article: Vitiligo Treated with Combined Piperine-Based Topical Treatment and Narrowband Ultraviolet B Therapy: Follow-Up with Reflectance Confocal Microscopy
Vitiligo Treated with Combined Piperine-Based Topical Treatment and Narrowband Ultraviolet B Therapy: Follow-Up with Reflectance Confocal Microscopy Open
Background: Reflectance confocal microscopy (RCM) has a defined in vivo morphology of vitiligo and re-pigmentation. Combination therapies seem more effective than monotherapies. Objective: We aim to describe the clinical and RCM features o…
View article: Long-Term Drug Survival and Effectiveness of Secukinumab in Patients with Moderate to Severe Chronic Plaque Psoriasis: 42-Month Results from the SUPREME 2.0 Study
Long-Term Drug Survival and Effectiveness of Secukinumab in Patients with Moderate to Severe Chronic Plaque Psoriasis: 42-Month Results from the SUPREME 2.0 Study Open
In this real-world cohort study, secukinumab showed consistently high long-term drug survival and effectiveness with a favourable safety profile.
View article: Dimethyl Fumarate Treatment in Patients with Moderate-to-Severe Psoriasis: A 52-week Real-life Study
Dimethyl Fumarate Treatment in Patients with Moderate-to-Severe Psoriasis: A 52-week Real-life Study Open
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View article: Atopic Dermatitis: Clinical Aspects and Unmet Needs
Atopic Dermatitis: Clinical Aspects and Unmet Needs Open
Atopic dermatitis is a common chronic-relapsing, inflammatory and itchy eczematous skin disorder which occurs in both children and adults. AD pathogenesis is complex and several factors are implicated. Pruritus plays a pivotal role in dise…
View article: Acral perineurioma: a case report of a rare neoplasm successfully treated with autologous skin graft reconstructive surgery
Acral perineurioma: a case report of a rare neoplasm successfully treated with autologous skin graft reconstructive surgery Open
Soft tissues perineurioma is a rare nerve sheath tumor that affects most of all the subcutaneous tissue. Even if it could present as a large mass, it is a benign neoplasm for whom a complete surgical excision represents the gold standard t…
View article: Patients Withdrawing Dupilumab Monotherapy for COVID-19–Related Reasons Showed Similar Disease Course Compared With Patients Continuing Dupilumab Therapy
Patients Withdrawing Dupilumab Monotherapy for COVID-19–Related Reasons Showed Similar Disease Course Compared With Patients Continuing Dupilumab Therapy Open
DermatitisVol. 33, No. 3 LettersFree AccessPatients Withdrawing Dupilumab Monotherapy for COVID-19–Related Reasons Showed Similar Disease Course Compared With Patients Continuing Dupilumab TherapyAndrea Chiricozzi, Lucia Di Nardo, Marina T…
View article: Dimethyl fumarate treatment for psoriasis in a real‐life setting: A multicentric retrospective study
Dimethyl fumarate treatment for psoriasis in a real‐life setting: A multicentric retrospective study Open
Dimethyl fumarate (DMF) is a fumaric acid esters derivate approved for plaque psoriasis as first-line systemic therapy. It has been available in Italy since 2017 and an increasing number of patients are treated with this drug. To evaluate …
View article: Management of patients with atopic dermatitis undergoing systemic therapy during COVID‐19 pandemic in Italy: Data from the DA‐COVID‐19 registry
Management of patients with atopic dermatitis undergoing systemic therapy during COVID‐19 pandemic in Italy: Data from the DA‐COVID‐19 registry Open
Background Few and small studies have described the management of immunomodulant/immunosuppressive therapies or phototherapy in atopic dermatitis (AD) patients during coronavirus disease 2019 (COVID‐19) pandemic. Methods A national registr…
View article: Management of patients with atopic dermatitis undergoing systemic therapy during COVID-19 pandemic in Italy: data from the DA-COVID-19 registry Running title: AD management during COVID-19 pandemic
Management of patients with atopic dermatitis undergoing systemic therapy during COVID-19 pandemic in Italy: data from the DA-COVID-19 registry Running title: AD management during COVID-19 pandemic Open
Background: Few and small studies have described the management of immunomodulant/immunosuppressive therapies or phototherapy in atopic dermatitis (AD) patients during coronavirus disease 2019 (COVID-19) pandemic. Methods: A national regis…
View article: Management of patients with atopic dermatitis undergoing systemic therapy during COVID-19 pandemic in Italy: data from the DA-COVID-19 registry
Management of patients with atopic dermatitis undergoing systemic therapy during COVID-19 pandemic in Italy: data from the DA-COVID-19 registry Open
Background: Few and small studies have described the management of immunomodulant/immunosuppressive therapies or phototherapy in atopic dermatitis (AD) patients during coronavirus disease 2019 (COVID-19) pandemic. Methods: A national regis…
View article: Phototherapy: The patients' point of view
Phototherapy: The patients' point of view Open
Phototherapy is a safe psoriasis treatment but it is quite time consuming. The patients' point of view is reported.
View article: Vitiligo management: combination of surgical treatment and phototherapy under reflectance confocal microscopy monitoring.
Vitiligo management: combination of surgical treatment and phototherapy under reflectance confocal microscopy monitoring. Open
Vitiligo is a psychosocially debilitating disease requiring a multidisciplinary approach. Even if a standard management could not be stated, combination of surgery and phototherapy in stable vitiligo could lead to great improvement than mo…
View article: Biological therapy in psoriatic patients whishing fatherhood: a multi‐centre italian experience in real life
Biological therapy in psoriatic patients whishing fatherhood: a multi‐centre italian experience in real life Open
Biological therapies have revolutionized the management of moderate‐to‐severe psoriasis in the last decade. However, if their impact on pregnancy outcomes has been recently investigated, data surrounding their effects after paternal exposu…
View article: Psoriasis and pregnancy outcomes in biological therapies: a real‐life, multi‐centre experience
Psoriasis and pregnancy outcomes in biological therapies: a real‐life, multi‐centre experience Open
We performed a retrospective study including 307 psoriatic women of childbearing age treated with biologics in 5 Dermatologic Center of University Hospitals (Modena, Bologna, Reggio Emilia, Parma and Ferrara) from 2004 to 2019. We defined …
View article: Secukinumab shows high efficacy irrespective of <i>HLA‐Cw6</i> status in patients with moderate‐to‐severe plaque‐type psoriasis: results from extension phase of the SUPREME study
Secukinumab shows high efficacy irrespective of <i>HLA‐Cw6</i> status in patients with moderate‐to‐severe plaque‐type psoriasis: results from extension phase of the SUPREME study Open
HLA-cw6 gene is associated with more severe and early onset psoriasis. Recent reports have shown that HLA-cw6 status predicts efficacy of some biologic treatments in psoriasis patients. Our study demonstrated that Secukinumab was equally e…
View article: PKCε promotes human Th17 differentiation: Implications in the pathophysiology of psoriasis
PKCε promotes human Th17 differentiation: Implications in the pathophysiology of psoriasis Open
PKCε is implicated in T cell activation and proliferation and is overexpressed in CD4 + ‐T cells from patients with autoimmune Hashimoto's thyroiditis. Although this might induce the suspicion that PKCε takes part in autoimmunity, its role…
View article: Claimed Effects, Outcome Variables and Methods of Measurement for Health Claims Proposed Under European Community Regulation 1924/2006 in the Framework of Maintenance of Skin Function
Claimed Effects, Outcome Variables and Methods of Measurement for Health Claims Proposed Under European Community Regulation 1924/2006 in the Framework of Maintenance of Skin Function Open
Evidence suggests a protective role for several nutrients and foods in the maintenance of skin function. Nevertheless, all the requests for authorization to use health claims under Article 13(5) in the framework of maintenance of skin func…
View article: Living with Chronic Spontaneous Urticaria in Italy: A Narrative Medicine Project to Improve the Pathway of Patient Care
Living with Chronic Spontaneous Urticaria in Italy: A Narrative Medicine Project to Improve the Pathway of Patient Care Open
Chronic spontaneous urticaria (CSU) is perceived as a difficult to manage disease with negative impact on quality of life. The aim of this study was to highlight how to improve the care of people with CSU, using the methodology of narrativ…
View article: Nutrition and Inflammation in Older Individuals: Focus on Vitamin D, n-3 Polyunsaturated Fatty Acids and Whey Proteins
Nutrition and Inflammation in Older Individuals: Focus on Vitamin D, n-3 Polyunsaturated Fatty Acids and Whey Proteins Open
Chronic activation of the inflammatory response, defined as inflammaging, is the key physio-pathological substrate for anabolic resistance, sarcopenia and frailty in older individuals. Nutrients can theoretically modulate this phenomenon. …
View article: Parental Use and Educational Campaigns on Sunbed Use Among Teenagers and Adolescents
Parental Use and Educational Campaigns on Sunbed Use Among Teenagers and Adolescents Open
This study aimed to evaluate the prevalence of sunbed use among teenagers and the association between familial behavior and the adoption of UV-protective practices in this age group. We also assessed the impact of an educational program on…
View article: Lesion presenting with a “blue amber” pattern
Lesion presenting with a “blue amber” pattern Open
Atypical fibroxanthoma (AFX) is a spindle cell neoplasm with low metastatic potential but high tendency to recur after surgery. Because of the rarity of this lesion and its aspecific clinical features, AFX could be easily misdiagnosed and …
View article: Supplementary Material for: Are Anti-TNF-α Agents Safe for Treating Psoriasis in Hepatitis C Virus Patients with Advanced Liver Disease? Case Reports and Review of the Literature
Supplementary Material for: Are Anti-TNF-α Agents Safe for Treating Psoriasis in Hepatitis C Virus Patients with Advanced Liver Disease? Case Reports and Review of the Literature Open
Tumor necrosis factor-alpha (TNF-α) inhibitors represent an effective treatment for severe psoriasis in hepatitis C virus (HCV) patients. The literature reports mainly on short-term treatment in patients with chronic hepatitis with minimum…