Sérgio Podgaec
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View article: Epidemiology with real-world data: deep endometriosis in women of reproductive age
Epidemiology with real-world data: deep endometriosis in women of reproductive age Open
Using real-world data, the prevalence of deep endometriosis was found to be 6.4% in women of reproductive age and 34.2% in those with pelvic pain. The primary clinical variables associated with endometriosis are palpable posterior cul-de-s…
View article: Nodular vulvar lesions and its key differential diagnoses: a case report
Nodular vulvar lesions and its key differential diagnoses: a case report Open
The etiologies of vulvar nodules range from infectious to neoplastic. Owing to the wide spectrum of vulvar diseases, clinical differentiation of the lesions is crucial for adequate diagnosis and management. A 46-year-old patient presented …
View article: High levels of a comprehensive set of matrix metalloproteinases in endometriotic lesions: validating the key role of cellular senescence in endometriosis pathogenesis
High levels of a comprehensive set of matrix metalloproteinases in endometriotic lesions: validating the key role of cellular senescence in endometriosis pathogenesis Open
Increased levels of MMP-1, MMP-2, and MMP-3 in endometriotic lesions indicate that endometriosis may have a unique metabolomic signature linked to cell cycle arrest and inflammation. This may contribute to the pathogenesis of endometriosis…
View article: Pelvic endometriosis: epidemiological and clinical profile prior to surgical treatment
Pelvic endometriosis: epidemiological and clinical profile prior to surgical treatment Open
SUMMARY OBJECTIVE: This study aims to analyze the epidemiological, sociodemographic, and clinical profile of women undergoing videolaparoscopic surgery for the treatment of pelvic endometriosis at the Hospital Israelita Albert Einstein. ME…
View article: Prenatal exposure to nitrate alters uterine morphology and gene expression in adult female F1 generation rats
Prenatal exposure to nitrate alters uterine morphology and gene expression in adult female F1 generation rats Open
Our results strongly suggest that prenatal exposure to nitrate programs gene expression and alters the uterine morphology in female F1 rats, potentially increasing their susceptibility to developing uterine diseases during adulthood.
View article: Internet use by pregnant women during prenatal care
Internet use by pregnant women during prenatal care Open
The search for health information by pregnant women is very prevalent but does not interfere with the delivery route.
View article: Nodular image in the appendix observed on ultrasound: endometriosis or neuroendocrine neoplasia?
Nodular image in the appendix observed on ultrasound: endometriosis or neuroendocrine neoplasia? Open
It was possible to observe a higher prevalence of appendix endometriosis when the patient presented more intense pain symptoms. The image observed on ultrasound obtained a high positive predictive value for appendicular endometriosis.
View article: The endometrioma paradox
The endometrioma paradox Open
Endometriosis is a chronic disease that affects around 10% of reproductive age women worldwide and a common cause of infertility. One of its manifestations is ovarian endometriomas, which are present in 17-44% of endometriosis patients. En…
View article: Follitropin delta combined with menotropin in patients at risk for poor ovarian response during in vitro fertilization cycles: a prospective controlled clinical study
Follitropin delta combined with menotropin in patients at risk for poor ovarian response during in vitro fertilization cycles: a prospective controlled clinical study Open
Background The maximum daily dose of follitropin delta for ovarian stimulation in the first in vitro fertilization cycle is 12 µg (180 IU), according to the algorithm developed by the manufacturer, and based on patient's ovarian reserve an…
View article: Superficial Endometriosis at Ultrasound Examination—A Diagnostic Criteria Proposal
Superficial Endometriosis at Ultrasound Examination—A Diagnostic Criteria Proposal Open
The actual prevalence of superficial endometriosis is not known. However, it is considered the most common subtype of endometriosis. The diagnosis of superficial endometriosis remains difficult. In fact, little is known about the ultrasoun…
View article: Higher Oxidative Stress in Endometriotic Lesions Upregulates Senescence-Associated p16ink4a and β-Galactosidase in Stromal Cells
Higher Oxidative Stress in Endometriotic Lesions Upregulates Senescence-Associated p16ink4a and β-Galactosidase in Stromal Cells Open
Endometriosis affects a significant proportion of women worldwide; however, no definitive cure for this disease has been discovered to date. Oxidative stress promotes endometriotic lesion maintenance in the peritoneal cavity in women. Furt…
View article: Brazilian Medical Survey on Telemedicine since the onset of COVID-19
Brazilian Medical Survey on Telemedicine since the onset of COVID-19 Open
Telemedicine has played a major role in healthcare since the onset of COVID-19 pandemic and most of the physicians approve its use and intend to continue using Telemedicine in their daily practice.
View article: EP140/#780 Vaginal hysterectomy for the treatment of low-risk endometrial cancer: interim surgical and oncological analysis
EP140/#780 Vaginal hysterectomy for the treatment of low-risk endometrial cancer: interim surgical and oncological analysis Open
Objectives The purpose of this study was to evaluate the role of vaginal hysterectomy for the treatment of patients with low-risk endometrial cancer. Methods We retrospectively reviewed the medical records of patients who underwent vaginal…
View article: Cervical Cancer-Related Knowledge, Attitudes, Practices and Self-Screening Acceptance Among Patients, Employees, and Social Media Followers of Major Brazilian Hospital
Cervical Cancer-Related Knowledge, Attitudes, Practices and Self-Screening Acceptance Among Patients, Employees, and Social Media Followers of Major Brazilian Hospital Open
Background Brazil has a high burden of cervical cancer, even though it is preventable, traceable and treatable. Hence, this study evaluated levels of knowledge, attitudes and practices (KAP) related to cervical cancer screening and diagnos…
View article: Cognitive Behavioral Therapy in Endometriosis, Psychological Based Intervention: A Systematic Review
Cognitive Behavioral Therapy in Endometriosis, Psychological Based Intervention: A Systematic Review Open
Introduction Endometriosis is an inflammatory disease that affects women of reproductive age, causing pain and the possibility of infertility. Endometriosis was associated to low life quality and research shows the impact of endometriosis …
View article: Altered p16Ink4a, IL-1β, and Lamin b1 Protein Expression Suggest Cellular Senescence in Deep Endometriotic Lesions
Altered p16Ink4a, IL-1β, and Lamin b1 Protein Expression Suggest Cellular Senescence in Deep Endometriotic Lesions Open
Endometriosis causes immunological and cellular alterations. Endometriosis lesions have lower levels of lamin b1 than the endometrium. Moreover, high levels of pro-inflammatory markers are observed in the peritoneal fluid, follicular fluid…
View article: Perioperative management in gynecological surgery based on the ERAS program
Perioperative management in gynecological surgery based on the ERAS program Open
Made available in DSpace on 2022-04-28T19:51:21Z (GMT). No. of bitstreams: 0\n Previous issue date: 2022-02-01
View article: Epidemiological profile and postoperative complications of women undergoing gynecological surgery in a reference center in the northern brazilian legal amazon
Epidemiological profile and postoperative complications of women undergoing gynecological surgery in a reference center in the northern brazilian legal amazon Open
Objective: To evaluate the epidemiological profile and the operative complications of patients undergoing gynecological operations for benign diseases in a tertiary public hospital in the state of Roraima, Brazil. Methods: We conducted a r…
View article: Sonographic signs of deep infiltrative endometriosis among women submitted to routine transvaginal sonography: clinical and imaging aspects
Sonographic signs of deep infiltrative endometriosis among women submitted to routine transvaginal sonography: clinical and imaging aspects Open
Routine transvaginal sonography offers an opportunity to search for signs of deep infiltrative endometriosis in oligosymptomatic women particularly those not previously suspected to have endometriosis.
View article: Cognitive Behavioral Therapy in Endometriosis, Psychological Based Intervention: A Systematic Review
Cognitive Behavioral Therapy in Endometriosis, Psychological Based Intervention: A Systematic Review Open
Introduction Endometriosis is an inflammatory disease that affects women of reproductive age, causing pain and the possibility of infertility. Endometriosis was associated to low life quality and research shows the impact of endometriosis …
View article: Patients with endometriosis using positive coping strategies have less depression, stress and pelvic pain
Patients with endometriosis using positive coping strategies have less depression, stress and pelvic pain Open
Objective To determine the correlations between coping strategies, depression, stress levels and pain perception in patients with endometriosis. Methods This prospective and exploratory study included 171 women undergoing treatment for end…
View article: Strategies to reduce the caesarean section rate in a private hospital and their impact
Strategies to reduce the caesarean section rate in a private hospital and their impact Open
There is a concern around the world of an increasing caesarean section rate. It was estimated that between 2010 and 2015, caesarean section rates increased by almost 50%. There are several implications for this, considering that caesarean …
View article: Epidemiological analysis of hysterectomies performed at the public health system in the largest Brazilian city
Epidemiological analysis of hysterectomies performed at the public health system in the largest Brazilian city Open
Despite the decrease in the number of hysterectomies over the 11-year study period in São Paulo, it remains in high demand mainly for the treatment of uterine leiomyomatosis. Laparoscopic hysterectomy has been gaining ground and showed a s…
View article: Freeze-all policy for in vitro fertilization in women with normal response to ovarian stimulation
Freeze-all policy for in vitro fertilization in women with normal response to ovarian stimulation Open
Freeze-all strategy was not superior to fresh transfer for all patients with normal response to ovarian stimulation. However, women aged 40 years and older could benefit from this strategy. This deserves further investigation in future res…