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View article: Reply to Gomez-Rojas, M.A.; Tung-Chen, Y. Comment on “Vicente-Rabaneda et al. A Proposal for a New Lung Ultrasound Score in Rheumatoid Arthritis: The Reliability of Lung Ultrasound for Rheumatoid Arthritis-Associated Interstitial Lung Disease Diagnosis. J. Clin. Med. 2025, 14, 3701”
Reply to Gomez-Rojas, M.A.; Tung-Chen, Y. Comment on “Vicente-Rabaneda et al. A Proposal for a New Lung Ultrasound Score in Rheumatoid Arthritis: The Reliability of Lung Ultrasound for Rheumatoid Arthritis-Associated Interstitial Lung Disease Diagnosis. J. Clin. Med. 2025, 14, 3701” Open
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View article: Anifrolumab in Systemic Lupus Erythematosus With Severe Hematological Manifestations: A Spanish Multicenter Study
Anifrolumab in Systemic Lupus Erythematosus With Severe Hematological Manifestations: A Spanish Multicenter Study Open
J Rheumatol 2025; doi: 10.3899/jrheum.2025-0658 In the 4th paragraph regarding severe hematological involvement, the criterion for severe leukopenia should be a leukocyte count of < 2 × 10 9 /L. The revised text is "severe leukopenia (leuk…
View article: Uncovering combination therapies for Immune-Mediated Inflammatory Diseases through systems biology analysis on longitudinal patient data 3497
Uncovering combination therapies for Immune-Mediated Inflammatory Diseases through systems biology analysis on longitudinal patient data 3497 Open
Description Despite advancements in targeted therapies, most patients with immune-mediated inflammatory diseases (IMIDs) fail to achieve sustained remission. Combining existing drugs has the potential to overcome this. We performed bulk an…
View article: Can Vitamin D Reduce Glucocorticoid-Induced Adverse Effects in Patients with Giant Cell Arteritis? Results from 1568 Patients in the Spanish ARTESER Registry
Can Vitamin D Reduce Glucocorticoid-Induced Adverse Effects in Patients with Giant Cell Arteritis? Results from 1568 Patients in the Spanish ARTESER Registry Open
Objective: To determine whether oral vitamin D supplementation reduces the risk of glucocorticoid (GC)-associated severe adverse events (SAEs) in patients with giant cell arteritis (GCA) included in the Spanish ARTESER registry. Methods: T…
View article: #1993 Recommendations on management of adult-onset IgA vasculitis proposed by the European IgA vasculitis study group
#1993 Recommendations on management of adult-onset IgA vasculitis proposed by the European IgA vasculitis study group Open
Background and Aims IgA vasculitis (IgAV) is a small-vessel vasculitis with predominant IgA deposits that involves the skin, the joints, the gastrointestinal tract and the kidneys, causing glomerulonephritis pathologically indistinguishabl…
View article: Disease activity predicts the development of cardiovascular events in patients with rheumatoid arthritis from the CARMA cohort
Disease activity predicts the development of cardiovascular events in patients with rheumatoid arthritis from the CARMA cohort Open
Disease activity is a key determinant of CV outcomes in RA patients. The PREVENT-CVD score is an effective tool for CV risk stratification in this population.
View article: Genome‐wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients
Genome‐wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients Open
Objectives Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation sign…
View article: Treatment and Evolution of 134 Patients With Aortitis and Periaortitis. Experience of a Third Level University Hospital
Treatment and Evolution of 134 Patients With Aortitis and Periaortitis. Experience of a Third Level University Hospital Open
Objective Aortitis and periaortitis include a heterogeneous group of conditions, which may be idiopathic or secondary to infectious diseases or non-infectious inflammatory disorders. Therefore, treatment differ considerably depending on th…
View article: Epidemiology, Clinical Features and Treatment of Neurosarcoidosis in Northern Spain
Epidemiology, Clinical Features and Treatment of Neurosarcoidosis in Northern Spain Open
Objectives: Neurosarcoidosis (NS) is a severe and infrequent complication of sarcoidosis. Available data on NS are variable. We aimed to characterize NS epidemiology, clinical and therapeutic characteristics in a well-defined cohort of NS …
View article: A Proposal for a New Lung Ultrasound Score in Rheumatoid Arthritis: The Reliability of Lung Ultrasound for Rheumatoid Arthritis-Associated Interstitial Lung Disease Diagnosis
A Proposal for a New Lung Ultrasound Score in Rheumatoid Arthritis: The Reliability of Lung Ultrasound for Rheumatoid Arthritis-Associated Interstitial Lung Disease Diagnosis Open
Background/Objectives: The objective of this study is to investigate the intra- and inter-explorer reliability of different lung ultrasound (LUS) scores in patients with suspected rheumatoid arthritis with associated interstitial lung dise…
View article: Revisiting the epidemiology of giant cell arteritis
Revisiting the epidemiology of giant cell arteritis Open
In this article, we review the epidemiology of giant cell arteritis (GCA), the most common form of vasculitis in older adults, which primarily affects large and medium-sized arteries. We discuss various epidemiological aspects of GCA, incl…
View article: Treatment of Ocular Sarcoidosis. Study of 65 Patients From a Series of 342 From a University Hospital in Northern Spain
Treatment of Ocular Sarcoidosis. Study of 65 Patients From a Series of 342 From a University Hospital in Northern Spain Open
Ocular involvement in sarcoidosis is frequent. Our aim was to evaluate visual outcomes and treatment in a cohort of patients with ocular sarcoidosis. Retrospective study of 342 patients with sarcoidosis from 1999 to 2019 in a university ho…
View article: The Metabolic Score for Insulin Resistance (METS-IR), a Predictor of Cardiovascular Events, Relates to Disease Activity in Patients with Rheumatoid Arthritis
The Metabolic Score for Insulin Resistance (METS-IR), a Predictor of Cardiovascular Events, Relates to Disease Activity in Patients with Rheumatoid Arthritis Open
Background: The Metabolic Score for Insulin Resistance (METS-IR) is a newly developed index that has been described to predict cardiovascular (CV) events. In this study, we calculated the METS-IR index in patients with rheumatoid arthritis…
View article: The role of multicriteria decision analysis in the development of candidate classification criteria for antisynthetase syndrome: analysis from the CLASS project
The role of multicriteria decision analysis in the development of candidate classification criteria for antisynthetase syndrome: analysis from the CLASS project Open
The MCDA-driven candidate classification criteria were consistent with published ASSD literature and yielded high accuracy and validity.
View article: Genome-wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients
Genome-wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients Open
Objectives Giant cell arteritis (GCA) is a large-vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation sign…
View article: Associations Between Soluble Cell Adhesion Molecules and Cardiovascular Comorbidities in Systemic Sclerosis: Implications for Insulin Resistance
Associations Between Soluble Cell Adhesion Molecules and Cardiovascular Comorbidities in Systemic Sclerosis: Implications for Insulin Resistance Open
Background: Soluble cell adhesion molecules such as sICAM-1 (soluble intercellular adhesion molecule-1), sVCAM-1 (soluble vascular cell adhesion molecule-1), and P-selectin have been implicated in cardiovascular disease pathogenesis in the…
View article: Severe Respiratory Infections in Rheumatoid Arthritis Patients: An Observational Study of 528 Patients from a Single University Hospital
Severe Respiratory Infections in Rheumatoid Arthritis Patients: An Observational Study of 528 Patients from a Single University Hospital Open
Patients with rheumatoid arthritis (RA) have an increased risk of infections. This may be linked to disease-related factors, immunosuppressive therapy and the presence of comorbidities. Background/Objectives: In an unselected group of RA p…
View article: Tocilizumab in Extracranial Giant-Cell Arteritis and Takayasu Arteritis: A Multicentric Observational Comparative Study
Tocilizumab in Extracranial Giant-Cell Arteritis and Takayasu Arteritis: A Multicentric Observational Comparative Study Open
Tocilizumab (TCZ) has demonstrated potential efficacy in managing large-vessel (LV) vasculitis such as giant-cell arteritis (GCA) and Takayasu arteritis (TAK). Despite the shared characteristics between the LV-GCA phenotype and TAK, there …
View article: Non-Classical Complications of Adult-Onset Still’s Disease: A Multicenter Spanish Study
Non-Classical Complications of Adult-Onset Still’s Disease: A Multicenter Spanish Study Open
Objective: To investigate the prevalence and clinical spectrum of atypical or non-classical complications in adult-onset Still’s disease (AOSD) beyond macrophage activation syndrome (MAS) and to identify factors linked to their occurrence.…
View article: Clinical Profiles, Survival, and Lung Function Outcomes in ANCA-Associated Interstitial Lung Disease: An Observational Study
Clinical Profiles, Survival, and Lung Function Outcomes in ANCA-Associated Interstitial Lung Disease: An Observational Study Open
Background/Objectives: Anti-neutrophil cytoplasmic antibodies (ANCAs) have been found in interstitial lung disease (ILD) in recent years, although its impact on ILD prognosis is less known. To date, ANCAs are not included in the interstiti…
View article: The metabolic score for insulin resistance predicts the risk of cardiovascular disease in patients with psoriatic arthritis: results from the 10-year prospective CARMA cohort
The metabolic score for insulin resistance predicts the risk of cardiovascular disease in patients with psoriatic arthritis: results from the 10-year prospective CARMA cohort Open
Objective To evaluate the predictive value of the metabolic score for insulin resistance (METS-IR) in identifying patients with psoriatic arthritis (PsA) at high risk of cardiovascular (CV) events. Methods Assessment of patients with PsA e…