Serhat Bor
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View article: Epithelial Barrier Function and Altered Cell Signaling Pathways in the Esophageal Epithelium of Achalasia Patients
Epithelial Barrier Function and Altered Cell Signaling Pathways in the Esophageal Epithelium of Achalasia Patients Open
Background/Aims: Idiopathic achalasia is a rare esophageal motility disorder of unknown etiology. Although its neuromuscular aspects are well described, little is known about the role of the esophageal epithelium. This study aimed to evalu…
View article: European Consensus on Functional Bloating and Abdominal Distension—An ESNM/UEG Recommendations for Clinical Management
European Consensus on Functional Bloating and Abdominal Distension—An ESNM/UEG Recommendations for Clinical Management Open
Introduction Abdominal distension is an objective visible sign of increased abdominal girth. Bloating is a feeling of abdominal fullness and discomfort. Bloating may be associated or not with abdominal distension. Bloating and abdominal di…
View article: Normal Values in Esophageal High-Resolution Manometry Performed Using 36-Channel Water-Perfused Catheter or Solid-State Catheter
Normal Values in Esophageal High-Resolution Manometry Performed Using 36-Channel Water-Perfused Catheter or Solid-State Catheter Open
Background/Aims: Manometric measurements are crucial for diagnosing esophageal motility disorders. High-resolution manometry (HRM) studies mainly use 2 catheter systems: solid state (SS) and water perfused (WP), each with distinct advantag…
View article: Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility
Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility Open
Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dy…
View article: Psychological and Clinical Factors Mediate Post‐<scp>COVID</scp>‐19 Irritable Bowel Syndrome
Psychological and Clinical Factors Mediate Post‐<span>COVID</span>‐19 Irritable Bowel Syndrome Open
Background Exposure to COVID‐19 has been shown previously to be associated with a higher risk for irritable bowel syndrome (IBS). This study aimed to better explain this relationship using mediation analysis. Methods This post hoc analysis…
View article: Long‐Term Impact of COVID‐19 on Disorders of Gut–Brain Interaction: Incidence, Symptom Burden, and Psychological Comorbidities
Long‐Term Impact of COVID‐19 on Disorders of Gut–Brain Interaction: Incidence, Symptom Burden, and Psychological Comorbidities Open
Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic has highlighted the potential exacerbation of gastrointestinal symptoms in patients with disorders of gut‐brain interaction (DGBIs). However, the distinct…
View article: Inflammatory responses in esophageal mucosa before and after laparoscopic antireflux surgery
Inflammatory responses in esophageal mucosa before and after laparoscopic antireflux surgery Open
BACKGROUND Currently, the primary treatment for gastroesophageal reflux is acid suppression with proton pump inhibitors, but they are not a cure, and some patients don’t respond well or refuse long-term use. Therefore, alternative therapie…
View article: Roles of Cytokines in Pathological and Physiological Gastroesophageal Reflux Exposure
Roles of Cytokines in Pathological and Physiological Gastroesophageal Reflux Exposure Open
"Microinflammation" in physiological acid exposure groups indicates that even a mild trigger is sufficient for the initiation and progression of inflammatory activity. Additionally, the anti-inflammatory cytokines were highly increased. Th…
View article: Revisiting the Role of Esophageal Mucosal Dilated Intercellular Spaces in the Diagnosis and Pathophysiology of Heartburn
Revisiting the Role of Esophageal Mucosal Dilated Intercellular Spaces in the Diagnosis and Pathophysiology of Heartburn Open
Since the IS length measurement had better discrimination power only in erosive groups, it is not feasible to use in daily routine to discriminate other nonerosive phenotypes and FH. The role of DIS in heartburn in nonerosive patients shou…
View article: The Prevalence of Gastroesophageal Reflux Disease in Azerbaijan: A Population-Based Cross-sectional Study
The Prevalence of Gastroesophageal Reflux Disease in Azerbaijan: A Population-Based Cross-sectional Study Open
Gender, body mass index, increased age, marital status, and stress were precipitating factors of gastroesophageal reflux disease. Socioeconomic diversity, along with lifestyle/habits, did not play a crucial role in the gastroesophageal ref…
View article: Computer-Based Intelligent Solutions for the Diagnosis of Gastroesophageal Reflux Disease Phenotypes and Chicago Classification 3.0
Computer-Based Intelligent Solutions for the Diagnosis of Gastroesophageal Reflux Disease Phenotypes and Chicago Classification 3.0 Open
Gastroesophageal reflux disease (GERD) is a multidisciplinary disease; therefore, when treating GERD, a large amount of data needs to be monitored and managed.The aim of our study was to develop a novel automation and decision support syst…
View article: The Abdominal Ultrasonography Results of Cappadocia Cohort Study of Turkey Reveals High Prevalence of Fatty Liver
The Abdominal Ultrasonography Results of Cappadocia Cohort Study of Turkey Reveals High Prevalence of Fatty Liver Open
Cappadocia cohort study in Turkey revealed a high prevalence of hepatic steatosis (60.1%) while the prevalence of gallbladder stones was 7.6% among the participants. The results of the Cappadocia cohort located in central Anatolia, where o…
View article: Inflammatory responses in esophageal mucosa before and after laparoscopic antireflux surgery
Inflammatory responses in esophageal mucosa before and after laparoscopic antireflux surgery Open
Supplementary files of the manuscript.
View article: Epigenetic Alterations from Barrett’s Esophagus to Esophageal Adenocarcinoma
Epigenetic Alterations from Barrett’s Esophagus to Esophageal Adenocarcinoma Open
Barrett’s esophagus (BE) is a disease entity that is a sequela of chronic gastroesophageal reflux disease that may result in esophageal adenocarcinoma (EAC) due to columnar epithelial dysplasia. The histological degree of dysplasia is the …
View article: Face‐to‐face interviews versus Internet surveys: Comparison of two data collection methods in the Rome foundation global epidemiology study: Implications for population‐based research
Face‐to‐face interviews versus Internet surveys: Comparison of two data collection methods in the Rome foundation global epidemiology study: Implications for population‐based research Open
Background and Aims The Rome Foundation Global Epidemiology Study (RFGES) assessed the prevalence, burden, and associated factors of Disorders of Gut–Brain Interaction (DGBI) in 33 countries around the world. Achieving worldwide sampling n…
View article: Dyssynergic Defecation: A Comprehensive Review on Diagnosis and Management
Dyssynergic Defecation: A Comprehensive Review on Diagnosis and Management Open
About one-third of chronically constipated patients have an evacuation disorder, and dyssynergic defecation is a common cause of the evacuation disorder. In dyssynergic defecation, the coordination between abdominal and pelvic floor muscle…
View article: Post COVID-19 irritable bowel syndrome
Post COVID-19 irritable bowel syndrome Open
Objectives The long-term consequences of COVID-19 infection on the gastrointestinal tract remain unclear. Here, we aimed to evaluate the prevalence of gastrointestinal symptoms and post-COVID-19 disorders of gut–brain interaction after hos…
View article: Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility
Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility Open
Irritable bowel syndrome with diarrhoea (IBS‐D) and functional diarrhoea (FDr) are the two major functional bowel disorders characterized by diarrhoea. In spite of their high prevalence, IBS‐D and FDr are associated with major uncertaintie…
View article: In Vitro and In Vivo Effects of Nonsteroidal Anti-inflammatory Drugs and Aspirin on Rabbit Esophageal Epithelium
In Vitro and In Vivo Effects of Nonsteroidal Anti-inflammatory Drugs and Aspirin on Rabbit Esophageal Epithelium Open
Nonsteroidal anti-inflammatory drugs were harmful to the rabbit esophageal epithelium in both the in vitro and in vivo experiments. Even though aspirin and ibuprofen affected the transport mechanisms of the esophageal epithelium, the dose-…
View article: Prevalence of Gastrointestinal Symptoms in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Results of the Prospective Controlled Multinational GI-COVID-19 Study
Prevalence of Gastrointestinal Symptoms in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Results of the Prospective Controlled Multinational GI-COVID-19 Study Open
INTRODUCTION: Gastrointestinal (GI) symptoms in coronavirus-19 disease (COVID-19) have been reported with great variability and without standardization. In hospitalized patients, we aimed to evaluate the prevalence of GI symptoms, factors …
View article: United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia
United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia Open
Background Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its definition, underlying pathophysiology, diagnosis, treatm…
View article: United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis
United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis Open
In the below-referenced article,1 the name of one of the authors in the ESNM Gastroparesis Consensus Group was misspelled. D. Kestzhelyi's name should have been listed as D. Keszthelyi. Additionally, Jolien Schol and Lucas Wauters should b…
View article: Validation of the Reflux Disease Questionnaire for a Turkish Population
Validation of the Reflux Disease Questionnaire for a Turkish Population Open
Background and Aims: Achieving the correct diagnosis and therapeutic success in gastroesophageal reflux disease (GERD) depends on the patient‘s self-assessment. Therefore, valid and reliable patient-reported questionnaires are very importa…
View article: United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia
United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia Open
Background Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its definition, underlying pathophysiology, diagnosis, treatm…
View article: Chicago Classification update (v4.0): Technical review of high‐resolution manometry metrics for EGJ barrier function
Chicago Classification update (v4.0): Technical review of high‐resolution manometry metrics for EGJ barrier function Open
Esophagogastric junction (EGJ) barrier function is of fundamental importance in the pathophysiology of gastroesophageal reflux disease. Impaired EGJ barrier function leads to excessive distal esophageal acid exposure or, in severe cases, e…
View article: Efficacy of pinaverium bromide in the treatment of irritable bowel syndrome: a systematic review and meta-analysis
Efficacy of pinaverium bromide in the treatment of irritable bowel syndrome: a systematic review and meta-analysis Open
Background: Spasmolytic agents are an attractive first line treatment option for irritable bowel syndrome (IBS). Pinaverium bromide (pinaverium) has antispasmodic effects on gastrointestinal smooth muscle and can relieve major IBS symptoms…
View article: Functional Bowel Disorders in Patients with Brugada Syndrome and Drug-Induced Type 1 Brugada Pattern
Functional Bowel Disorders in Patients with Brugada Syndrome and Drug-Induced Type 1 Brugada Pattern Open
Introduction: Irritable bowel syndrome (IBS) is one of the most widely recognized functional bowel disorders (FBDs) with a genetic component. SCN5A gene and SCN1B loci have been identified in population-based IBS cohorts and proposed to ha…