Explanipedia

Evaluation of the Efficacy and Safety of CollaSel PRO® Type I and Type III Hydrolyzed Collagen Peptides in the Treatment of Osteoarthritis: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial Open

Devrim Demir Dora, Serpil Tuna, Emel Doğan Kurtoğlu, Savaş Gürsoy, Nilüfer Balcı , et al. · 2025

Objectives: This study aims to evaluate the efficacy and safety of oral supplementation with hydrolyzed collagen peptides (HCP) type I and type III (CollaSel PRO®) in reducing joint pain and stiffness and improving physical function in pat…

The Impact of Repeated Applications of Botulinum Toxin A on the Spasticity of the Upper Limb in Stroke Patient, Cohort Study Open

Nilüfer Aygün Bilecik, Serpil Tuna, Özlem Karataş, Nilüfer Balcı · 2025

Background: Spasticity is a muscle stiffness issue often caused by spinal cord or cerebral diseases, notably impairing stroke patients. This study aims to evaluate the long-term effectiveness of repeated Botulinum Toxin A injections on spa…

Assessing ChatGPT’s Role in Sarcopenia and Nutrition: Insights from a Descriptive Study on AI-Driven Solutions Open

Özlem Karataş, Seden Demirci, Kaan Pota, Serpil Tuna · 2025

Background: Sarcopenia, an age-related decline in muscle mass and function, poses significant health risks. While AI tools like ChatGPT-4 (ChatGPT-4o) are increasingly used in healthcare, their accuracy in addressing sarcopenia remains unc…

Relationship Between Sarcopenia, Femoral Cartilage Thickness, and Knee Osteoarthritis: Case–Control Study Open

Serpil Tuna, Ethem Kavukçu, Nilüfer Balcı · 2025

Objective This study aims to evaluate the association between femoral cartilage thickness (FCT) and knee osteoarthritis (KO) in individuals with sarcopenia and pre‐sarcopenia, highlighting the potential role of FCT in the relationship betw…

Comparison of Retinal Microvascular Changes in Axial Spondyloarthritis Using Optical Coherence Tomography Angiography: Anti-TNF vs. NSAID Therapy Open

Özlem Karataş, Çisil Erkan Pota, Bülent Akyüz, Yusuf Samet Atlıhan, Kaan Pota , et al. · 2025

Objectives: The aim of this study was to investigate retinal and choroidal microvascular changes in patients with axial spondyloarthritis (axSpA) treated with long-term anti-TNF therapy and NSAIDs and in healthy control subjects using opti…

Neuropathic pain in knee osteoarthritis: Prevalence, diagnosis, and clinical implications Open

Özlem Karataş, Dilek Yapar, Aliekber Yapar, Serpil Tuna, Hakan Çetin , et al. · 2025

Neuropathic pain is common in KOA patients and is associated with higher pain intensity and poorer functional outcomes. The moderate agreement between the painDETECT and DN4 scores may lead to a certain degree of diagnostic variation. Comb…

Is Skin Thinning a Natural Consequence of Aging or a Result of Sarcopenia? A Case-Control Study Open

Serpil Tuna, Sevil Eren · 2024

Background: It is widely accepted that skin thickness decreases and fragility increases with aging. However, the relationship between skin thickness and sarcopenia, a common condition in the elderly associated with an increased risk of fra…

Variations of tuberculin skin test in patients with rheumatologic disorders and under anti-TNF treatment Open

Tayfun Özdemir, Serpil Tuna, Özlem Karataş, Mehmet Arman · 2019

Aim: Nowadays PPD is the most inexpensive and easy to apply modality of test in identification of latent tuberculosis infection. Isoniazid (INH) prophylaxis must be given before usage of anti-TNF-α agents for patients. We aimed to investig…

AB0759 Neuropathic pain prevalence in psoriatic arthritis and its correlation with disease activity Open

HE Öz, Serpil Tuna, Ülkü Uçar, Nilüfer Balci Vedin · 2017

Dermatological side effects in rheumatological patients taking anti TNF-α treatment Open

Serpil Tuna, Sevil Alan, Ülkü Uçar, Mehmet Arman · 2016

INTRODUCTION: In this study, we aimed to investigate dermatological side effects DSE seen in patients with rheumatic diseases taking TNF-α blocker. METHODS: A total number of 103 patients with chronic inflammatory rheumatic diseases on TNF…

Neutrophil/Lymphocyte Ratio, Platelet/Lymphocyte Ratio and Mean Platelet Volume in Behçet Disease Patients with and without Ocular Involvement Open

Elif Betül Türkoğlu, Sevil Alan, Serpil Tuna, Aslı ÇETİNKAYA, Yaşar Tuna · 2016

Objective:To evaluate the relationship between neutrophil/lymphocyte ratio (NLR), mean platelet volume (MPV), and platelet/lymphocyte ratio (PLR) and risk of ocular involvement in Behçet Disease (BD). Material and Methods: This prospective…

Is There an Association between Restless Legs Syndrome and Urticaria? Open

Serpil Tuna, Sevil Alan, Nehir Samancı, Ayşe Akman Karakaş · 2016

Restless legs syndrome (RLS) is a disease characterized by the urge to move the legs and sleep disturbances. Similarly, chronic spontaneous urticaria (CSU) is a dermatological disease characterized by pruritus and sleep disorders. In this …

Limbus Vertebra Presenting with Inflammatory Low Back Pain: A Case Report Open

Serpil Tuna, Tayfun Özdemir, Hande Ece Öz · 2016

Limbus vertebra is a condition characterized by marginal interosseous herniation of the nucleus pulposus, and causes non specific symptoms like low back pain, back pain, muscle spasms and radiculopathy. It is frequently confused with verte…

Common Mistakes in the Dual-Energy X-ray Absorptiometry (DXA) in Turkey. A Retrospective Descriptive Multicenter Study Open

Ali Yavuz Karahan, Buğra Kaya, Banu Kuran, Özlem Altındağ, Pelin Yıldırım , et al. · 2016

Background: Osteoporosis is a widespread metabolic bone disease representing a global public health problem currently affecting more than two hundred million people worldwide. The World Health Organization states that dual-energy X-ray abs…

Effects of Smoking and HLA-B51 on Clinical Manifestations in Behçet’s Disease: Retrospective Analysis of 209 Patients in a Turkish Population Open

Serpil Tuna · 2015

Objectives: This study aims to investigate the separate and cumulative effects of smoking and human leukocyte antigen (HLA)-B51 on the severity and clinical manifestations of Behçet’s disease (BD). Patients and methods: A total of 209 pati…

The nailfold videocapillaroscopy findings of Behçet's syndrome Open

Sevil Alan, Ayşe Balkarlı, Serpil Tuna, Ümit Özkan, Şahin Temel , et al. · 2015

Background: Nailfold videocapillaroscopy (NVC) is a diagnostic method for evaluating the microvasculature. Behçet's disease (BD) can affect vessels of all types and sizes. Methods: We performed NVC in 82 randomly selected patients with BD.…

The relation of neutrophil‐to‐lymphocyte ratio, platelet‐to‐lymphocyte ratio, and mean platelet volume with the presence and severity of Behçet's syndrome Open

Sevil Alan, Serpil Tuna, Elif Betül Türkoğlu · 2015

Behçet's syndrome (BS) is associated with chronic inflammation and endothelial dysfunction. Although there have been extensive investigations on neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), and mean platelet vo…

Effect of Systemic Infliximab Therapy in Patients with Sjögren’s Syndrome Open

Elif Betül Türkoğlu, Serpil Tuna, Sevil Alan, Mehmet Arman, Yaşar Tuna , et al. · 2015

Infliximab therapy, which is commonly used in systemic autoimmune diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, and ankylosing spondylitis, did not show a positive effect on ocular surface and tear function te…

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