Seth Newton
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View article: Mixed contaminant exposure in tapwater and the potential implications for human-health in disadvantaged communities in California
Mixed contaminant exposure in tapwater and the potential implications for human-health in disadvantaged communities in California Open
Water is an increasingly precious resource in California as years of drought, climate change, pollution, as well as an expanding population have all stressed the state's drinking water supplies. Currently, there are increasing concerns abo…
View article: Development and Application of a Non-Targeted Analysis Method Using Gc-Ms and Lc-Ms for Identifying Chemical Contaminants in Drinking Water Via Point-of-Use Filters
Development and Application of a Non-Targeted Analysis Method Using Gc-Ms and Lc-Ms for Identifying Chemical Contaminants in Drinking Water Via Point-of-Use Filters Open
View article: Practical application guide for the discovery of novel PFAS in environmental samples using high resolution mass spectrometry
Practical application guide for the discovery of novel PFAS in environmental samples using high resolution mass spectrometry Open
View article: Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome
Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome Open
View article: The use of gas chromatography – high resolution mass spectrometry for suspect screening and non-targeted analysis of per- and polyfluoroalkyl substances
The use of gas chromatography – high resolution mass spectrometry for suspect screening and non-targeted analysis of per- and polyfluoroalkyl substances Open
View article: Demonstrating the Use of Non-targeted Analysis for Identification of Unknown Chemicals in Rapid Response Scenarios
Demonstrating the Use of Non-targeted Analysis for Identification of Unknown Chemicals in Rapid Response Scenarios Open
Several thousand intentional and unintentional chemical releases occur annually in the U.S., with the contents of almost 30% being of unknown composition. When targeted methods are unable to identify the chemicals present, alternative appr…
View article: Approaches for assessing performance of high-resolution mass spectrometry–based non-targeted analysis methods
Approaches for assessing performance of high-resolution mass spectrometry–based non-targeted analysis methods Open
View article: The Use of Gas Chromatography – High Resolution Mass Spectrometry for Suspect Screening and Non-Targeted Analysis of Polyfluorinated Alkyl Substances (PFAS)
The Use of Gas Chromatography – High Resolution Mass Spectrometry for Suspect Screening and Non-Targeted Analysis of Polyfluorinated Alkyl Substances (PFAS) Open
View article: An Introduction to the Benchmarking and Publications for Non-Targeted Analysis Working Group
An Introduction to the Benchmarking and Publications for Non-Targeted Analysis Working Group Open
Non-targeted analysis (NTA) encompasses a rapidly evolving set of mass spectrometry techniques aimed at characterizing the chemical composition of complex samples, identifying unknown compounds, and/or classifying samples, without prior kn…
View article: A Framework for Utilizing High-Resolution Mass Spectrometry and Nontargeted Analysis in Rapid Response and Emergency Situations
A Framework for Utilizing High-Resolution Mass Spectrometry and Nontargeted Analysis in Rapid Response and Emergency Situations Open
Unknown chemical releases constitute a large portion of the rapid response situations to which the US Environmental Protection Agency is called on to respond. Workflows used to address unknown chemical releases currently involve screening …
View article: Semi-quantitative non-targeted analysis as a rapid risk prioritization tool: A proof of concept using activated carbon drinking water filters
Semi-quantitative non-targeted analysis as a rapid risk prioritization tool: A proof of concept using activated carbon drinking water filters Open
Presentation to the QSAR 2021 International Workshop on QSAR in Environmental and Health Sciences June 2021 Search for CCTE records in EPA’s Science Inventory by typing in the title at this link. https://cfpub.epa.gov/si/si_public_search_…
View article: Semi-Quantitative Non-Targeted Analysis as a Rapid Risk Prioritization Tool: A Proof of Concept Using Activated Carbon Drinking Water Filters
Semi-Quantitative Non-Targeted Analysis as a Rapid Risk Prioritization Tool: A Proof of Concept Using Activated Carbon Drinking Water Filters Open
Presentation to the ACS Spring 2021 National Meeting in April 2021
View article: Evidence of Air Dispersion: HFPO–DA and PFOA in Ohio and West Virginia Surface Water and Soil near a Fluoropolymer Production Facility
Evidence of Air Dispersion: HFPO–DA and PFOA in Ohio and West Virginia Surface Water and Soil near a Fluoropolymer Production Facility Open
Perfluorooctanoic acid (PFOA) was used as a fluoropolymer manufacturing aid at a fluoropolymer production facility in Parkersburg, WV from 1951 to 2013. The manufacturer introduced a replacement surfactant hexafluoropropylene oxide dimer a…
View article: Examining NTA performance and potential using fortified and reference house dust as part of EPA’s Non-Targeted Analysis Collaborative Trial (ENTACT)
Examining NTA performance and potential using fortified and reference house dust as part of EPA’s Non-Targeted Analysis Collaborative Trial (ENTACT) Open
View article: Establishing universal non-targeted analysis vocabulary and reporting recommendations: An update from the Benchmarking and Publications for Non-Targeted Analysis (BP4NTA) working group
Establishing universal non-targeted analysis vocabulary and reporting recommendations: An update from the Benchmarking and Publications for Non-Targeted Analysis (BP4NTA) working group Open
Presentation given to the SETAC North America Annual Conference November 2020
View article: EPA’s Research Initiatives on Non-Targeted Analyses of Environmental Chemicals
EPA’s Research Initiatives on Non-Targeted Analyses of Environmental Chemicals Open
Presentation given to the American Chemical Society Fall 2020 Meeting, August 2020
View article: New approach methodologies for exposure science
New approach methodologies for exposure science Open
View article: The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency
The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency Open
The U.S. Environmental Protection Agency (EPA) is faced with the challenge of efficiently and credibly evaluating chemical safety often with limited or no available toxicity data. The expanding number of chemicals found in commerce and the…
View article: Per- and polyfluoroalkyl substances in two different populations of northern cardinals
Per- and polyfluoroalkyl substances in two different populations of northern cardinals Open
View article: Using prepared mixtures of ToxCast chemicals to evaluate non-targeted analysis (NTA) method performance
Using prepared mixtures of ToxCast chemicals to evaluate non-targeted analysis (NTA) method performance Open
View article: The ENTACT Story: Using US EPA Resources to Evaluate and Enhance Non-target Workflows
The ENTACT Story: Using US EPA Resources to Evaluate and Enhance Non-target Workflows Open
Presentation given to the Solutions and Workflows in (Environmental) Molecular Screening and Analysis (SWEMSA) 2019 Conference October 2019
View article: EPA’s non-targeted analysis collaborative trial (ENTACT): genesis, design, and initial findings
EPA’s non-targeted analysis collaborative trial (ENTACT): genesis, design, and initial findings Open
View article: Comparison of emerging contaminants in receiving waters downstream of a conventional wastewater treatment plant and a forest-water reuse system
Comparison of emerging contaminants in receiving waters downstream of a conventional wastewater treatment plant and a forest-water reuse system Open
View article: Using the US EPA’s CompTox Chemistry Dashboard to advance non-targeted analysis and exposure research
Using the US EPA’s CompTox Chemistry Dashboard to advance non-targeted analysis and exposure research Open
Presentation at the ISES Annual Meeting Oct 2017
View article: Structure identification by Mass Spectrometry Non-Targeted Analysis using the US EPA’s CompTox Chemistry Dashboard
Structure identification by Mass Spectrometry Non-Targeted Analysis using the US EPA’s CompTox Chemistry Dashboard Open
Identification of unknowns in mass spectrometry based non-targeted analyses (NTA) requires the integration of complementary pieces of data to arrive at a confident, consensus structure. Researchers use chemical reference databases, spectra…
View article: Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA
Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA Open
View article: Suspect screening and non-targeted analysis of drinking water using point-of-use filters
Suspect screening and non-targeted analysis of drinking water using point-of-use filters Open
View article: Novel Polyfluorinated Compounds Identified Using High Resolution Mass Spectrometry Downstream of Manufacturing Facilities near Decatur, Alabama
Novel Polyfluorinated Compounds Identified Using High Resolution Mass Spectrometry Downstream of Manufacturing Facilities near Decatur, Alabama Open
Concern over persistence, bioaccumulation, and toxicity has led to international regulation and phase-outs of certain perfluorinated compounds and little is known about their replacement products. High resolution mass spectrometry was used…
View article: Comparisons of indoor active and passive air sampling methods for emerging and legacy halogenated flame retardants in Beijing, China offices
Comparisons of indoor active and passive air sampling methods for emerging and legacy halogenated flame retardants in Beijing, China offices Open
View article: Concentrations of legacy and emerging flame retardants in air and soil on a transect in the UK West Midlands
Concentrations of legacy and emerging flame retardants in air and soil on a transect in the UK West Midlands Open