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View article: Metagenomic Analysis Reveals Large‐Scale Disruptions of the Gut Microbiome in Parkinson's Disease
Metagenomic Analysis Reveals Large‐Scale Disruptions of the Gut Microbiome in Parkinson's Disease Open
Background Parkinson's disease (PD) has been consistently linked to alterations within the gut microbiome. Objective Our goal was to identify microbial features associated with PD incidence and progression. Methods Metagenomic sequencing w…
View article: MicroRNAs in thyroid cancer with focus on medullary thyroid carcinoma: potential therapeutic targets and diagnostic/prognostic markers and web based tools
MicroRNAs in thyroid cancer with focus on medullary thyroid carcinoma: potential therapeutic targets and diagnostic/prognostic markers and web based tools Open
This review aimed to describe the inculpation of microRNAs (miRNAs) in thyroid cancer (TC) and its subtypes, mainly medullary thyroid carcinoma (MTC), and to outline web-based tools and databases for bioinformatics analysis of miRNAs in TC…
View article: Recent Developments in Cell Line Shipping Methods: Pivotal Gaps in Cellular Death Sciences
Recent Developments in Cell Line Shipping Methods: Pivotal Gaps in Cellular Death Sciences Open
Contrary to remarkable advances within the cell therapy industry, scientists expose dissatisfied challenges associated with the preservation and post-thaw cell death globally. Post cryopreservation apoptosis is normally observed in culture…
View article: The impact of pre‐analytical variations on biochemical analytes stability: A systematic review
The impact of pre‐analytical variations on biochemical analytes stability: A systematic review Open
Objective A common problem in clinical laboratories is maintaining the stability of analytes during pre‐analytical processes. The aim of this study was to systematically summarize the results of a set of studies about the biochemical analy…
View article: Versican V1 Overexpression Induces a Myofibroblast-Like Phenotype in Cultured Fibroblasts
Versican V1 Overexpression Induces a Myofibroblast-Like Phenotype in Cultured Fibroblasts Open
Collectively, these data indicate versican expression induces a myofibroblast-like phenotype in cultured fibroblasts.
View article: 1,25 Dihydroxyvitamin D3 Inhibits TGFβ1-Mediated Primary Human Cardiac Myofibroblast Activation
1,25 Dihydroxyvitamin D3 Inhibits TGFβ1-Mediated Primary Human Cardiac Myofibroblast Activation Open
Our results demonstrate that active vitamin D can prevent TGFβ1-mediated biochemical and functional pro-fibrotic changes in human primary cardiac fibroblasts. An inverse relationship between vitamin D status and cardiac fibrosis in end sta…