Yong Rok Lee
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View article: The innate immune protein calprotectin incapacitates the bactericidal activity of β-lactam antibiotics
The innate immune protein calprotectin incapacitates the bactericidal activity of β-lactam antibiotics Open
β-lactam antibiotics are widely used to treat bacterial infections, yet treatment failures frequently occur even without resistance. Here, we show that the innate immune protein calprotectin (CP), released by neutrophils and abundant at in…
View article: Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins via complexation
Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins via complexation Open
The solubility of commonly used anti-inflammatory drugs has become a significant concern in contemporary medicine. Furthermore, inflammatory arthritis stands out as the most prevalent chronic inflammatory disease globally. The disease's pa…
View article: Enhancing ketoprofen's solubility and anti-inflammatory efficacy with safe methyl-β-cyclodextrin complexation
Enhancing ketoprofen's solubility and anti-inflammatory efficacy with safe methyl-β-cyclodextrin complexation Open
Improved solubility and anti-inflammatory (AI) properties are imperative for enhancing the effectiveness of poorly water-soluble drugs, particularly non-steroidal anti-inflammatory drugs (NSAIDs). To address these critical issues, our focu…
View article: Synthesis, Characterization, and Evaluation of Silver Nanoparticle-Loaded Carboxymethyl Chitosan with Sulfobetaine Methacrylate Hydrogel Nanocomposites for Biomedical Applications
Synthesis, Characterization, and Evaluation of Silver Nanoparticle-Loaded Carboxymethyl Chitosan with Sulfobetaine Methacrylate Hydrogel Nanocomposites for Biomedical Applications Open
In this study, nanocomposites of AgNPs encapsulated in carboxymethyl chitosan (CMCS) with sulfobetaine methacrylate (SB) hydrogel (AgNPs/CMCS-SB) were synthesized. The UV-Vis spectra indicated the presence of AgNPs, with a broad peak at ar…
View article: Functionalized 2-Hydrazinobenzothiazole with Bithiophene as a Colorimetric Sensor for Lethal Cyanide Ions and Its Application in Food Samples
Functionalized 2-Hydrazinobenzothiazole with Bithiophene as a Colorimetric Sensor for Lethal Cyanide Ions and Its Application in Food Samples Open
A newly synthesized Schiff's base 2-(2-([2,2'-bithiophen]-5-ylmethylene)hydrazinyl)benzothiazole (BT) was obtained from the condensation reaction between 2-hydrazinobenzothiazole and 2,2-bithiophene-5-carboxaldehyde. The prepared pr…
View article: CCDC 2297276: Experimental Crystal Structure Determination
CCDC 2297276: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2297282: Experimental Crystal Structure Determination
CCDC 2297282: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2271279: Experimental Crystal Structure Determination
CCDC 2271279: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2271290: Experimental Crystal Structure Determination
CCDC 2271290: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Synthesis of Photoluminescent Carbon Dots Using Hibiscus Tea Waste and Heteroatom Doping for Multi-Metal Ion Sensing: Applications in Cell imaging and Environmental Samples
Synthesis of Photoluminescent Carbon Dots Using Hibiscus Tea Waste and Heteroatom Doping for Multi-Metal Ion Sensing: Applications in Cell imaging and Environmental Samples Open
Novel photoluminescent carbon dots (CDs) were synthesized through a facile hydrothermal method using Hibiscus tea extract as a natural carbon source and boric acid as a boron source. The optical and physicochemical properties of the as-syn…
View article: Adenosine/β-Cyclodextrin-Based Metal–Organic Frameworks as a Potential Material for Cancer Therapy
Adenosine/β-Cyclodextrin-Based Metal–Organic Frameworks as a Potential Material for Cancer Therapy Open
Recently, researchers have employed metal–organic frameworks (MOFs) for loading pharmaceutically important substances. MOFs are a novel class of porous class of materials formed by the self-assembly of organic ligands and metal ions, creat…
View article: CCDC 2232662: Experimental Crystal Structure Determination
CCDC 2232662: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2264243: Experimental Crystal Structure Determination
CCDC 2264243: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Preparation and Characterization of a Nano-Inclusion Complex of Quercetin with β-Cyclodextrin and Its Potential Activity on Cancer Cells
Preparation and Characterization of a Nano-Inclusion Complex of Quercetin with β-Cyclodextrin and Its Potential Activity on Cancer Cells Open
Quercetin (QRC), a flavonoid found in foods and plants such as red wine, onions, green tea, apples, and berries, possesses remarkable anti-inflammatory and antioxidant properties. These properties make it effective in combating cancer cell…
View article: Facile Synthesis of Functionalized Porous Carbon by Direct Pyrolysis of Anacardium occidentale Nut-Skin Waste and Its Utilization towards Supercapacitors
Facile Synthesis of Functionalized Porous Carbon by Direct Pyrolysis of Anacardium occidentale Nut-Skin Waste and Its Utilization towards Supercapacitors Open
Preparing electrode materials plays an essential role in the fabrication of high-performance supercapacitors. In general, heteroatom doping in carbon-based electrode materials enhances the electrochemical properties. Herein, nitrogen, oxyg…
View article: Supramolecular β-Cyclodextrin-Quercetin Based Metal–Organic Frameworks as an Efficient Antibiofilm and Antifungal Agent
Supramolecular β-Cyclodextrin-Quercetin Based Metal–Organic Frameworks as an Efficient Antibiofilm and Antifungal Agent Open
The loading of drugs or medicinally active compounds has recently been performed using metal–organic frameworks (MOFs), which are thought to be a new type of porous material in which organic ligands and metal ions can self-assemble to form…
View article: CCDC 2156411: Experimental Crystal Structure Determination
CCDC 2156411: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Eco-Friendly Synthesis of Functionalized Carbon Nanodots from Cashew Nut Skin Waste for Bioimaging
Eco-Friendly Synthesis of Functionalized Carbon Nanodots from Cashew Nut Skin Waste for Bioimaging Open
In this study, Anacardium occidentale (A. occidentale) nut skin waste (cashew nut skin waste) was used as a raw material to synthesize functionalized carbon nanodots (F-CNDs). A. occidentale biomass-derived F-CNDs were synthesized at a low…
View article: Biowaste-Derived Heteroatom-Doped Porous Carbon as a Sustainable Electrocatalyst for Hydrogen Evolution Reaction
Biowaste-Derived Heteroatom-Doped Porous Carbon as a Sustainable Electrocatalyst for Hydrogen Evolution Reaction Open
Heteroatom-doped porous carbon material (H-PCM) was synthesized using Anacardium occidentale (cashew) nut’s skin by a simple pyrolysis route. The resulting H-PCM was thoroughly characterized by various analytical techniques such as field e…
View article: Water Soluble PMPC-Derived Bright Fluorescent Nitrogen/Phosphorous-Doped Carbon Dots for Fluorescent Ink (Anti-Counterfeiting) and Cellular Multicolor Imaging
Water Soluble PMPC-Derived Bright Fluorescent Nitrogen/Phosphorous-Doped Carbon Dots for Fluorescent Ink (Anti-Counterfeiting) and Cellular Multicolor Imaging Open
Here, a simple one-step hydrothermal-assisted carbonization process was adopted for the preparation of nitrogen/phosphorous-doped carbon dots from a water-soluble polymer, poly 2-(methacryloyloxy)ethyl phosphorylcholine (PMPC). By the free…
View article: Tenofovir antiviral drug solubility enhancement with β-cyclodextrin inclusion complex and in silico study of potential inhibitor against SARS-CoV-2 main protease (Mpro)
Tenofovir antiviral drug solubility enhancement with β-cyclodextrin inclusion complex and in silico study of potential inhibitor against SARS-CoV-2 main protease (Mpro) Open
View article: Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application
Novel Microwave Synthesis of Copper Oxide Nanoparticles and Appraisal of the Antibacterial Application Open
The exceptional characteristics of bio-synthesized copper oxide nanoparticles (CuO NPs), including high surface-to-volume ratio and high-profit strength, are of tremendous interest. CuO NPs have cytotoxic, catalytic, antibacterial, and ant…
View article: NiCo2S4/MoS2 Nanocomposites for Long-Life High-Performance Hybrid Supercapacitors
NiCo2S4/MoS2 Nanocomposites for Long-Life High-Performance Hybrid Supercapacitors Open
Metal sulfides (MS) and mixed metal sulfides (MTMS) have been considered potential candidates over their metal oxide/mixed metal oxide counterparts in recent years. Herein, one MTMS, i.e., NiCo2S4, was combined with 2D MS MoS2 through a si…
View article: Effect of proton ion concentration on the supramolecular interaction between phenoxazine and β-cyclodextrin
Effect of proton ion concentration on the supramolecular interaction between phenoxazine and β-cyclodextrin Open
In aqueous and β-cyclodextrin (β-CD) media, the spectral characteristics of phenoxazine (POZ) have been investigated by means of absorption, steady-state, and time-resolved fluorescence techniques. The stoichiometric ratio of the mono-cati…
View article: Natural Nitrogen-Doped Carbon Dots Obtained from Hydrothermal Carbonization of Chebulic Myrobalan and Their Sensing Ability toward Heavy Metal Ions
Natural Nitrogen-Doped Carbon Dots Obtained from Hydrothermal Carbonization of Chebulic Myrobalan and Their Sensing Ability toward Heavy Metal Ions Open
Chebulic Myrobalan is the main ingredient in the Ayurvedic formulation Triphala, which is used for kidney and liver dysfunctions. Herein, natural nitrogen-doped carbon dots (NN-CDs) were prepared from the hydrothermal carbonization of Cheb…
View article: Poly(caffeic acid) Redox Couple Decorated on Electrochemically Reduced Graphene Oxide for Electrocatalytic Sensing Free Chlorine in Drinking Water
Poly(caffeic acid) Redox Couple Decorated on Electrochemically Reduced Graphene Oxide for Electrocatalytic Sensing Free Chlorine in Drinking Water Open
Regular water quality measurements are essential to the public water supply. Moreover, selective free chlorine (disinfectant) level monitoring without an interfering agent is necessary. The present work aimed to fabricate poly(caffeic acid…
View article: One Pot Synthesis of Copper Oxide Nanoparticles for Efficient Antibacterial Activity
One Pot Synthesis of Copper Oxide Nanoparticles for Efficient Antibacterial Activity Open
The unique semiconductor and optical properties of copper oxides have attracted researchers for decades. However, using fruit waste materials such as peels to synthesize the nanoparticles of copper oxide (CuO NPs) has been rarely described…
View article: A Review of Biomass-Derived Heterogeneous Catalysts for Biodiesel Production
A Review of Biomass-Derived Heterogeneous Catalysts for Biodiesel Production Open
The scientific community is being forced to consider alternative renewable fuels such as biodiesel as a result of the sharp increases in the price of petroleum and the increased demand for petroleum-derived products. Transesterification is…
View article: Sustainable Synthesis of Bright Fluorescent Nitrogen-Doped Carbon Dots from Terminalia chebula for In Vitro Imaging
Sustainable Synthesis of Bright Fluorescent Nitrogen-Doped Carbon Dots from Terminalia chebula for In Vitro Imaging Open
In this study, sustainable, low-cost, and environmentally friendly biomass (Terminalia chebula) was employed as a precursor for the formation of nitrogen-doped carbon dots (N-CDs). The hydrothermally assisted Terminalia chebula fruit-deriv…
View article: Synthesis of active-site rich molybdenum-doped manganese tungstate nanocubes for effective electrochemical sensing of the antiviral drug (COVID-19) nitazoxanide
Synthesis of active-site rich molybdenum-doped manganese tungstate nanocubes for effective electrochemical sensing of the antiviral drug (COVID-19) nitazoxanide Open