Seung‐Hyuk Choi
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View article: Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation
Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation Open
Background The optimal antiplatelet regimen after standard endovascular aneurysm repair (EVAR) in patients without atherosclerotic cardiovascular disease remains uncertain. Clinical guidelines offer limited recommendations, and data specif…
View article: Long‐Term Prognostic Value of the Prognostic Nutritional Index in Patients Undergoing Coronary Artery Bypass Grafting
Long‐Term Prognostic Value of the Prognostic Nutritional Index in Patients Undergoing Coronary Artery Bypass Grafting Open
Background The Prognostic Nutritional Index (PNI) as an indicator of nutritional and immunological status has been widely applied in various medical conditions. However, its prognostic role in postoperative outcomes after coronary artery b…
View article: Clinical Relevance of Fractional Flow Reserve‐Guided Percutaneous Coronary Intervention According to Left Ventricular Ejection Fraction in Patients With Acute Myocardial Infarction and Multivessel Disease
Clinical Relevance of Fractional Flow Reserve‐Guided Percutaneous Coronary Intervention According to Left Ventricular Ejection Fraction in Patients With Acute Myocardial Infarction and Multivessel Disease Open
Background Fractional flow reserve (FFR)‐guided or angiography‐guided complete revascularization has not been evaluated in patients with acute myocardial infarction (AMI) with multivessel disease and reduced left ventricular ejection fract…
View article: Evaluation of neurocognitive function changes based on the full neuropsychological test battery after transcatheter aortic valve replacement under monitored anaesthesia care
Evaluation of neurocognitive function changes based on the full neuropsychological test battery after transcatheter aortic valve replacement under monitored anaesthesia care Open
BACKGROUND: In elderly patients undergoing transcatheter aortic valve replacement (TAVR), preserving cognitive function and early detection of cognitive decline are important for maintaining quality of life after the procedure. While studi…
View article: Anthropometric analysis of the palpebral fissure using superimposition of 3D CBCT models and photographs for forensic facial reconstruction in young Korean adults
Anthropometric analysis of the palpebral fissure using superimposition of 3D CBCT models and photographs for forensic facial reconstruction in young Korean adults Open
Facial reconstruction in forensic anthropology is a technique to identify individuals from skeletal remains. This process is heavily reliant on accurately estimating facial features, particularly the eyes, which are the most distinctive fe…
View article: The effects of extracorporeal blood purification (oXiris®) in patients with cardiogenic shock who require VA-ECMO (CLEAN ECMO): a prospective, open-label, randomized controlled pilot study
The effects of extracorporeal blood purification (oXiris®) in patients with cardiogenic shock who require VA-ECMO (CLEAN ECMO): a prospective, open-label, randomized controlled pilot study Open
NCT05642273, registered 8 December 2022.
View article: Efficacy of Extended Dual Antiplatelet Therapy After Coronary Artery Bypass Grafting in Patients With High Inflammatory Risk
Efficacy of Extended Dual Antiplatelet Therapy After Coronary Artery Bypass Grafting in Patients With High Inflammatory Risk Open
In CABG patients with high inflammatory risk, prolonged DAPT (≥12 months) was associated with significantly lower rates of all-cause death or MI compared with SAPT.
View article: Clinical significance of low-density lipoprotein cholesterol percentage reduction and attained levels after percutaneous coronary intervention
Clinical significance of low-density lipoprotein cholesterol percentage reduction and attained levels after percutaneous coronary intervention Open
ClinicalTrials.gov, NCT06338956.
View article: Potent P2Y12 inhibitors in patients with acute myocardial infarction and cardiogenic shock
Potent P2Y12 inhibitors in patients with acute myocardial infarction and cardiogenic shock Open
In patients with AMI complicated by cardiogenic shock, the use of potent P2Y12 inhibitors was associated with a lower risk of MACE compared with clopidogrel, without an increased risk of BARC type 2 or greater bleeding. The curr…
View article: Differential Prognosis of True Bifurcation Lesions According to Left Main Versus Non–Left Main Location and Treatment Strategy
Differential Prognosis of True Bifurcation Lesions According to Left Main Versus Non–Left Main Location and Treatment Strategy Open
Background Although true bifurcation lesions are associated with a high risk of procedural complications, the differential prognostic implications of percutaneous coronary intervention for true bifurcations according to lesion location are…
View article: Effect of Operator Experience Performing Rotational Atherectomy on Clinical Outcomes After Percutaneous Coronary Intervention
Effect of Operator Experience Performing Rotational Atherectomy on Clinical Outcomes After Percutaneous Coronary Intervention Open
In PCI using RA for calcified lesions, the composite outcome of cardiac death, myocardial infarction, and target vessel revascularization at 1 year was not significantly different according to RA experience among operators.
View article: Sex Differences in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation
Sex Differences in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation Open
ClinicalTrials.gov Identifier: NCT02985008.
View article: Comparison of High-Dose versus Low-Dose Paclitaxel Drug-Coated Balloons for Native Femoropopliteal Artery Disease: An Analysis of the K-VIS ELLA Registry
Comparison of High-Dose versus Low-Dose Paclitaxel Drug-Coated Balloons for Native Femoropopliteal Artery Disease: An Analysis of the K-VIS ELLA Registry Open
In this multicenter cohort study of patients with complex FPA disease, there were no significant differences between high-dose DCB and low-dose DCB with respect to freedom from clinically driven TLR, MALE, or all-cause mortality at 12-mont…
View article: Outcomes of Deferring Percutaneous Coronary Intervention Without Physiologic Assessment for Intermediate Coronary Lesions
Outcomes of Deferring Percutaneous Coronary Intervention Without Physiologic Assessment for Intermediate Coronary Lesions Open
ClinicalTrials.gov Identifier: NCT00743899.
View article: Comparative Efficacy of High-Dose Rosuvastatin and Atorvastatin in Preventing Cystatin C-Oriented Contrast-Induced Nephropathy in Patients With Acute Myocardial Infarction: RACCOON-AMI Registry
Comparative Efficacy of High-Dose Rosuvastatin and Atorvastatin in Preventing Cystatin C-Oriented Contrast-Induced Nephropathy in Patients With Acute Myocardial Infarction: RACCOON-AMI Registry Open
Clinical Research Information Service Identifier: KCT0003703.
View article: Clinical Impact of Sarcopenia Screening on Long‐Term Mortality in Patients Undergoing Coronary Bypass Grafting
Clinical Impact of Sarcopenia Screening on Long‐Term Mortality in Patients Undergoing Coronary Bypass Grafting Open
Background Sarcopenia is an aging‐related condition characterized by loss of skeletal muscle mass and is an indicator of subclinical atherosclerosis. The relationship between reduced muscle mass and long‐term clinical outcomes in patients …
View article: STK33 as the functional substrate of miR-454-3p for suppression and apoptosis in neuroblastoma
STK33 as the functional substrate of miR-454-3p for suppression and apoptosis in neuroblastoma Open
miR-454-3p has been reported to be a tumor-suppressive microRNA (miRNA) in multiple cancer types. We identified the kinase STK33 mRNA, which is a high-risk factor for survival in neuroblastoma (NB) patients, as being a substrate of miR-454…
View article: β-PIX-d, a Member of the ARHGEF7 Guanine Nucleotide Exchange Factor Family, Activates Rac1 and Induces Neuritogenesis in Primary Cortical Neurons
β-PIX-d, a Member of the ARHGEF7 Guanine Nucleotide Exchange Factor Family, Activates Rac1 and Induces Neuritogenesis in Primary Cortical Neurons Open
β-PIX, a Rac1/Cdc42-specific guanine nucleotide exchange factor, is known to regulate actin cytoskeleton remodeling during cell migration. In this study, we investigated the effects of β-PIX-d, an isoform of β-PIX, on neocortical developme…
View article: Morphometric analysis of the hard palate in sex estimation among koreans using three-dimensional computed tomography
Morphometric analysis of the hard palate in sex estimation among koreans using three-dimensional computed tomography Open
Accurate sex estimation is crucial for comprehensive analysis of the biological profiles of unidentified human skeletal remains. However, there is a notable lack of research specifically addressing the morphometrics of the hard palate. The…
View article: Sex Difference in 5-year Relative Survival Following Percutaneous Coronary Intervention
Sex Difference in 5-year Relative Survival Following Percutaneous Coronary Intervention Open
Background: Survival rates following percutaneous coronary intervention (PCI) show variability across studies, particularly regarding sex-specific outcomes. Relative survival analysis, which considers survival patterns in sex- and age-matc…
View article: Improved Localization of Unmanned Underwater Vehicle via Cooperative Navigation of Unmanned Surface Vehicle Equipped with Ultrashort Baseline
Improved Localization of Unmanned Underwater Vehicle via Cooperative Navigation of Unmanned Surface Vehicle Equipped with Ultrashort Baseline Open
View article: Drug-coated balloon versus drug-eluting stent for femoropopliteal total occlusions: intraluminal versus subintimal approaches
Drug-coated balloon versus drug-eluting stent for femoropopliteal total occlusions: intraluminal versus subintimal approaches Open
Because there is a lack of comparative studies assessing drug-coated balloon (DCB) and drug-eluting stent (DES) outcomes with respect to intraluminal (IL) and subintimal (SI) approaches in femoropopliteal (FP) total occlusive lesions, we c…
View article: Fractional Flow Reserve and Fractional Flow Reserve Gradient From CCTA for Predicting Future Coronary Events
Fractional Flow Reserve and Fractional Flow Reserve Gradient From CCTA for Predicting Future Coronary Events Open
View article: Transfusion and clinical outcomes after percutaneous coronary intervention
Transfusion and clinical outcomes after percutaneous coronary intervention Open
We investigated the long-term patterns and effects of transfusion on the clinical outcome of patients undergoing percutaneous coronary intervention (PCI) using a nationwide registry. Five-year clinical outcome of all Koreans undergoing PCI…
View article: Discontinuation of β-blocker therapy in stabilised patients after acute myocardial infarction (SMART-DECISION): rationale and design of the randomised controlled trial
Discontinuation of β-blocker therapy in stabilised patients after acute myocardial infarction (SMART-DECISION): rationale and design of the randomised controlled trial Open
Introduction There is a lack of evidence to support the effectiveness of prolonged β-blocker therapy after stabilisation of patients with acute myocardial infarction (AMI) without heart failure (HF) or left ventricular systolic dysfunction…
View article: Intravascular Imaging and Angiography Guidance in Complex Percutaneous Coronary Intervention Among Patients With Diabetes
Intravascular Imaging and Angiography Guidance in Complex Percutaneous Coronary Intervention Among Patients With Diabetes Open
Importance Data are limited regarding the effects of intravascular imaging guidance during complex percutaneous coronary intervention (PCI) in patients with diabetes. Objective To compare the clinical outcomes of intravascular imaging–guid…
View article: LGG-29. BEYOND MAPK SIGNALING - GENOME-SCALE CRISPR/CAS9 SCREENS REVEAL NEW TARGETS FOR TREATMENT OF KIAA1549::BRAF-DRIVEN PEDIATRIC LOW-GRADE GLIOMA
LGG-29. BEYOND MAPK SIGNALING - GENOME-SCALE CRISPR/CAS9 SCREENS REVEAL NEW TARGETS FOR TREATMENT OF KIAA1549::BRAF-DRIVEN PEDIATRIC LOW-GRADE GLIOMA Open
Since the KIAA1549::BRAF fusion was discovered as the most common driver of pediatric low-grade glioma (pLGG), it has been hypothesized that the fusion induces oncogenicity through BRAF activation as a result of KIAA1549 replacing the BRAF…
View article: Drug-Coated Balloon Angioplasty in Patients Undergoing Complex Percutaneous Coronary Intervention
Drug-Coated Balloon Angioplasty in Patients Undergoing Complex Percutaneous Coronary Intervention Open
View article: VA‐ECMO weaning strategy using adjusted pulse pressure by vasoactive inotropic score in AMI complicated by cardiogenic shock
VA‐ECMO weaning strategy using adjusted pulse pressure by vasoactive inotropic score in AMI complicated by cardiogenic shock Open
Aims This study evaluated how well serial pulse pressure (PP) and PP adjusted by the vasoactive inotropic score (VIS) predicted venoarterial extracorporeal membrane oxygenation (VA‐ECMO) weaning success and clinical outcomes in acute myoca…
View article: Prognostic Implications of N-Terminal Pro-B-Type Natriuretic Peptide in Patients With Non-ST-Elevation Myocardial Infarction
Prognostic Implications of N-Terminal Pro-B-Type Natriuretic Peptide in Patients With Non-ST-Elevation Myocardial Infarction Open
In patients with NSTEMI who underwent PCI, an initial elevated NT-proBNP concentration was associated with higher risk of MACE at 3 years, driven primarily by higher risks of cardiac death or admission for heart failure. These results sugg…