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View article: Chrysin protects neuronal cells against carboplatin exposure-induced apoptosis and oxidative damage
Chrysin protects neuronal cells against carboplatin exposure-induced apoptosis and oxidative damage Open
Chemotherapy drugs such as carboplatin are commonly used to treat various cancers, including testicular, lung, and ovarian cancer. Although carboplatin primarily targets cancer cells, it can also damage healthy cells, including neurons, le…
View article: 18β-glycyrrhetinic acid Mitigates bisphenol A-induced liver and renal damage: Inhibition of TNF-α/NF-κB/p38-MAPK, JAK1/STAT1 pathways, oxidative stress and apoptosis
18β-glycyrrhetinic acid Mitigates bisphenol A-induced liver and renal damage: Inhibition of TNF-α/NF-κB/p38-MAPK, JAK1/STAT1 pathways, oxidative stress and apoptosis Open
Bisphenol A (BPA) has been commonly used in various consumer products, including water bottles, food containers, and canned food linings. However, there are concerns about its potential toxicity to human health, particularly its impact on …
View article: Cisplatin Impact on Kasumi-1 Leukemia: Gene Expression and DNA Damage
Cisplatin Impact on Kasumi-1 Leukemia: Gene Expression and DNA Damage Open
Purpose: Leukemia is a type of cancer caused by the uncontrolled proliferation of blood cells. The purpose of this study was to investigate the effects of cisplatin (CIS), a chemotherapeutic agent used in the treatment of leukemia, on the …
View article: Green Synthesis of Apricot Kernel Silver Nanoparticles and Their Biological Activity
Green Synthesis of Apricot Kernel Silver Nanoparticles and Their Biological Activity Open
Silver nanoparticles (AgNPs) have been shown to have high conductivity, chemical stability, catalytic and antibacterial activities, as well as cytotoxicity on various cancer cells. Many biological resources, including plants, fungi, and ba…
View article: Investigation of the Apoptotic and Cell Cycle Effects of Sorafenib and Doxorubicin on URG4/URGCP in Leukemia Cells
Investigation of the Apoptotic and Cell Cycle Effects of Sorafenib and Doxorubicin on URG4/URGCP in Leukemia Cells Open
Leukemia, characterized by abnormal proliferation of blood cells, primarily affects leukocytes but can also impact other blood cells. Treatment typically involves stem cell transplants, radiotherapy, and chemotherapy, although chemotherapy…