Seyed Alireza Fahimzad
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View article: Secondary Bacterial Pneumonia in Pediatrics with Influenza and COVID-19
Secondary Bacterial Pneumonia in Pediatrics with Influenza and COVID-19 Open
Background: Differentiating between influenza, COVID-19, and secondary bacterial infections in hospitalized patients presents a significant challenge. Objectives: This study aimed to evaluate the occurrence of secondary bacterial pneumonia…
View article: Virulent genes related to the synthesis of community interaction factors among clinical samples of multidrug-resistant Acinetobacter baumannii in Iran
Virulent genes related to the synthesis of community interaction factors among clinical samples of multidrug-resistant Acinetobacter baumannii in Iran Open
Introduction: Acinetobacter (A.) baumannii poses a significant threat of resistance to multiple antibiotics. This study aimed to examine the prevalence of the abaI and bap genes in clinical isolates of multidrug-resistant A. baumannii coll…
View article: Prevalence of oral HPV infection and genotype distribution in Iranian children during the early ages of life
Prevalence of oral HPV infection and genotype distribution in Iranian children during the early ages of life Open
The present research indicates that oral HPV infection is quite common in early ages of Iranian children. Multiple HPV infections and a high prevalence of HPV16 are concerning issues for unknown consequences. Lack of full concordance of HP…
View article: Radiologic analysis of CT imaging patterns and clinical correlations in hospitalized pediatric COVID-19 patients
Radiologic analysis of CT imaging patterns and clinical correlations in hospitalized pediatric COVID-19 patients Open
Background and objective COVID-19 has emerged as a global pandemic affecting individuals of all ages. The disease can lead to severe complications and even death, particularly due to pulmonary involvement. Contrary to popular belief, child…
View article: Characterization of genes involved in the iron acquisition system of multidrug-resistant Acinetobacter baumannii
Characterization of genes involved in the iron acquisition system of multidrug-resistant Acinetobacter baumannii Open
Background: The high prevalence of virulence-associated genes observed in Acinetobacter baumannii isolates underscores the pathogenic potential of this bacterium. The presence of these genes confers enhanced survival, evasion of host defen…
View article: The intestinal carrier status of Enterococcus spp. in children: clonal diversity and alterations in resistance phenotypes before and after admission to a pediatric intensive care unit
The intestinal carrier status of Enterococcus spp. in children: clonal diversity and alterations in resistance phenotypes before and after admission to a pediatric intensive care unit Open
Background This study aimed to investigate the intestinal carrier status of Enterococcus spp. among children in a pediatric intensive care unit (PICU) and reveal the role of hospitalization in the alteration of resistance phenotypes and cl…
View article: Investigation of Clinical Manifestations and Laboratory Findings of COVID-19 During National Peaks of Alpha, Beta, Delta, and Omicron in the Pediatric Emergency Department of Mofid Children's Hospital, Tehran, Iran
Investigation of Clinical Manifestations and Laboratory Findings of COVID-19 During National Peaks of Alpha, Beta, Delta, and Omicron in the Pediatric Emergency Department of Mofid Children's Hospital, Tehran, Iran Open
Background: The global spread of the coronavirus since 2019 has caused significant concern. Objectives: In this study, we aimed to investigate the clinical manifestations and laboratory findings of children infected with the alpha, beta, d…
View article: Fecal carriage and enrichment of multidrug-resistant Enterococci among admitted children in a pediatric intensive care unit
Fecal carriage and enrichment of multidrug-resistant Enterococci among admitted children in a pediatric intensive care unit Open
Background : The present study aimed to investigate intestinal carrier’s status of Enterococcus spp. in children and revealing role of hospitalization on alteration of their resistance phenotype and clonal diversity during the admission an…
View article: Demographic, clinical, immunological, and molecular features of iranian national cohort of patients with defect in DCLRE1C gene
Demographic, clinical, immunological, and molecular features of iranian national cohort of patients with defect in DCLRE1C gene Open
Background DCLRE1C gene mutation leads to Artemis deficiency, a severe form of combined immunodeficiency (SCID). Impaired DNA repair and block in early adaptive immunity maturation results in T-B-NK+ immunodeficiency associated with radios…
View article: Antibiotic Susceptibility Patterns for Carbapenem-Resistant Enterobacteriaceae
Antibiotic Susceptibility Patterns for Carbapenem-Resistant Enterobacteriaceae Open
Carbapenem is a broad-spectrum beta-lactam antibiotic considered the last choice for the treatment of antibiotic-resistant Gram-negative bacteria. Thus, the increasing rate of carbapenem resistance (CR) in Enterobacteriaceae is an urgent p…
View article: Prevalence and Antimicrobial Resistance Patterns in ESKAPE Pathogens in Iran
Prevalence and Antimicrobial Resistance Patterns in ESKAPE Pathogens in Iran Open
Background: The spread of resistant bacteria has caused serious concern worldwide. The spread of multidrug-resistant (MDR) and extensive drug-resistant (XDR) limits the choice of antibiotics, making available antibiotics less effective. Ob…
View article: Assessment of early and post COVID-19 vaccination antibody response in healthcare workers: a multicentre cross-sectional study on inactivated, mRNA and vector-based vaccines
Assessment of early and post COVID-19 vaccination antibody response in healthcare workers: a multicentre cross-sectional study on inactivated, mRNA and vector-based vaccines Open
In this multicentre study, we compared the status of antibody production in healthcare personnel (HCP) before and after vaccination using different brands of COVID-19 vaccines between March 2021 and September 2021. Out of a total of 962 HC…
View article: Evaluate the Modified Carbapenem Inactivation Method for Phenotypic Detection of Carbapenemase Production Among Gram-Negative Bacteria
Evaluate the Modified Carbapenem Inactivation Method for Phenotypic Detection of Carbapenemase Production Among Gram-Negative Bacteria Open
Background: Global growing infections by multi-drug resistance (MDR) or extensively drug-resistant (XDR) bacteria are a serious public health problem which can increase the rate of mortality and morbidity even in children. Carbapenem is th…
View article: COVID-19 Mortality in Children: A Referral Center Experience from Iran (Mofid Children’s Hospital, Tehran, Iran)
COVID-19 Mortality in Children: A Referral Center Experience from Iran (Mofid Children’s Hospital, Tehran, Iran) Open
Background. The novel coronavirus disease 2019 (COVID-19) started in Wuhan, China, in December 2019. It spread widely around the world and was described as a pandemic by the World Health Organization (WHO). The knowledge regarding the mort…
View article: Re-positive PCR of SARS-CoV-2 in health care persons during COVID-19 pandemic
Re-positive PCR of SARS-CoV-2 in health care persons during COVID-19 pandemic Open
Reinfection rate with SARS-CoV-2 and degree of protection by the induced antibody after the first episode of the infection is not well known, so it makes a big dilemma for health care personnel (HCP) who work in the front line of combating…
View article: Corrigendum to: Development of a Novel Scoring System for Comprehensive COVID-19 Patient Evaluation: Evidence-Based Systematic Review
Corrigendum to: Development of a Novel Scoring System for Comprehensive COVID-19 Patient Evaluation: Evidence-Based Systematic Review Open
View article: Household contact investigation for the detection of active tuberculosis and latent tuberculosis: A comprehensive evaluation in two high-burden provinces in Iran
Household contact investigation for the detection of active tuberculosis and latent tuberculosis: A comprehensive evaluation in two high-burden provinces in Iran Open
View article: Evidence‐Based Prediction of COVID‐19 Severity in Hospitalized Children
Evidence‐Based Prediction of COVID‐19 Severity in Hospitalized Children Open
Objective . In this study, by using clinical and paraclinical characteristics, we have aimed to predict the severity of the disease in hospitalized COVID‐19 children. Method . This cross‐sectional study was conducted on medical records abo…
View article: Implementing the Protocol of Perioperative Narrow-spectrum Antibiotic Prophylaxis in the Surgical Wards of Mofid Children’s Hospital in 2019 - 2020, A Comparative Study
Implementing the Protocol of Perioperative Narrow-spectrum Antibiotic Prophylaxis in the Surgical Wards of Mofid Children’s Hospital in 2019 - 2020, A Comparative Study Open
Background: Surgical procedures may be complicated by post-surgical infections. This study investigates the role of administering perioperative narrow-spectrum antibiotic prophylaxis in preventing post-surgical infections as compared to ro…
View article: Clinical Course and Characteristics of COVID-19 in Patients With Inborn Errors of Immunity: A Retrospective Multicenter Experience From Iran
Clinical Course and Characteristics of COVID-19 in Patients With Inborn Errors of Immunity: A Retrospective Multicenter Experience From Iran Open
Purpose This study aimed to assess the effect of COVID-19 on patients with IEIs, the potentially at-risk population, regarding the clinical course, complications, severity, and outcomes. Methods This two-phase study was conducted on patien…
View article: Serotype Distribution of Streptococcus pneumoniae Carriage in Six-Month-Old Infants: A Cross-sectional Study During 2017-18, Tehran, Iran
Serotype Distribution of Streptococcus pneumoniae Carriage in Six-Month-Old Infants: A Cross-sectional Study During 2017-18, Tehran, Iran Open
Background: Streptococcus pneumoniae is recognized as one of the main pathogens inducing several invasive and non-invasive infections in children. Objective: The present study aimed to evaluate the serotype distribution of S. pneumoniae in…
View article: Acute Kidney Injury in Pediatric Patients with COVID-19; Clinical Features and Outcome
Acute Kidney Injury in Pediatric Patients with COVID-19; Clinical Features and Outcome Open
Background: Renal disorders are reported as both underlying conditions and complications in critical pediatric COVID-19 infection. Herein, we investigated the pattern of renal involvement, particularly acute kidney injury (AKI), among pedi…
View article: Knowledge, attitude and practice of Sari birth cohort members during early weeks of COVID-19 outbreak in Iran
Knowledge, attitude and practice of Sari birth cohort members during early weeks of COVID-19 outbreak in Iran Open
Background It has been determined that the coronavirus disease 2019 (COVID-19) pandemic needs social distancing and proper measures to prevent its spreading. This study aimed to determine COVID-19 knowledge, attitude, and practice among Sa…
View article: Life-threatening SARS-CoV-2 Infection in Children: A Single-center Case Series
Life-threatening SARS-CoV-2 Infection in Children: A Single-center Case Series Open
Introduction: Coronavirus disease 2019 (COVID-19) is known as the most recent pandemic condition declared by the World Health Organization (WHO). It is widely believed that this infection is less frequent and severe in children, but few mo…
View article: An Algorithmic Approach to Children’s Gastroenteritis in SARS-CoV-2 Epidemic: Iranian Expert’s Consensus Statement
An Algorithmic Approach to Children’s Gastroenteritis in SARS-CoV-2 Epidemic: Iranian Expert’s Consensus Statement Open
: Diarrhea and vomiting with or without fever are common symptoms in children, while one of the most common clinical findings of Coronavirus disease 2019 (COVID-19) is gastrointestinal symptoms. Therefore, there is a need to develop an alg…
View article: Is Alvarado Score Helpful for Pediatrician in Diagnosis of Acute Appendicitis? Our Center Experience
Is Alvarado Score Helpful for Pediatrician in Diagnosis of Acute Appendicitis? Our Center Experience Open
Background: Many problems in the diagnosis of patients with suspected appendicitis have led to the design of clinical scoring systems. In children, diagnostics tools for appendicitis are more critical. Younger patients, diagnostic challeng…
View article: Renal Involvement in COVID-19 Among Iranian Children
Renal Involvement in COVID-19 Among Iranian Children Open
Background: Information about renal involvement in pediatric patients with COVID-19 is limited, and there is not enough data about renal and urinary tract involvement in children infected with this novel virus. Objectives: This study aimed…
View article: An Algorithmic Approach to Management of COVID-19 Associated Multisystem Inflammatory Syndrome in Children
An Algorithmic Approach to Management of COVID-19 Associated Multisystem Inflammatory Syndrome in Children Open
View article: Development of a Novel Scoring System for Comprehensive COVID-19 Patient Evaluation: An Evidence-based Systematic Review
Development of a Novel Scoring System for Comprehensive COVID-19 Patient Evaluation: An Evidence-based Systematic Review Open
Context: In the era of the SARS-CoV-2 virus pandemic, new scoring systems need to be developed to estimate the risk of COVID-19 complications aiding in the accurate prognosis. Improved scoring systems by combining multiple variables allow …
View article: Prevalence of SARS-CoV-2 Specific Antibodies in the Staff of a Children's Hospital, in Tehran, Iran
Prevalence of SARS-CoV-2 Specific Antibodies in the Staff of a Children's Hospital, in Tehran, Iran Open
Background: In December 2019, a new coronavirus appeared in China, as a cause of acute respiratory disease. Healthcare Workers (HCWs) in children's hospitals are one of the groups who are at a high rate of exposure to COVID-19 patients. Th…