Seyed Mohammad Tavangar
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View article: Exogenous phosphatidylserine protects against mesenteric ischemia-reperfusion with associated Akt/mTOR pathway upregulation
Exogenous phosphatidylserine protects against mesenteric ischemia-reperfusion with associated Akt/mTOR pathway upregulation Open
Acute mesenteric ischemia-reperfusion is a life-threatening condition that causes severe intestinal injury through oxidative stress, inflammation, and apoptosis. Despite its high mortality rate, no pharmacological treatment is currently av…
View article: Niclosamide as a Neuroprotective and Anti-Inflammatory Agent: A Potential Therapeutic Approach for Spinal Cord Injury
Niclosamide as a Neuroprotective and Anti-Inflammatory Agent: A Potential Therapeutic Approach for Spinal Cord Injury Open
Spinal cord injury (SCI) is a life-altering condition of the central nervous system resulting in permanent motor, sensory, and functional deficits. The pathophysiology involved includes: primary neuronal necrosis, secondary inflammation, o…
View article: Linezolid mitigates tissue injury in experimental model of pediatric testicular torsion: TLR-4/MAPK/NF-κB involvement
Linezolid mitigates tissue injury in experimental model of pediatric testicular torsion: TLR-4/MAPK/NF-κB involvement Open
Background: Testicular torsion is a urological emergency that requires prompt surgery to prevent orchiectomy. Pharmacological interventions may slow the progression of damage and reduce reperfusion injury after surgical correction.Purpose:…
View article: Effects of Gap 26, a Connexin 43 Inhibitor, on Cirrhotic Cardiomyopathy in Rats
Effects of Gap 26, a Connexin 43 Inhibitor, on Cirrhotic Cardiomyopathy in Rats Open
View article: Exploring the role of tumor to background parenchymal ratio of the [18F]FLT PET/CT measures in determining response to neoadjuvant chemotherapy in breast cancer: a multicenter study
Exploring the role of tumor to background parenchymal ratio of the [18F]FLT PET/CT measures in determining response to neoadjuvant chemotherapy in breast cancer: a multicenter study Open
View article: A novel long noncoding RNA, PICSAR, promotes thyroid cancer progression through the hsa-miR-320A/hsa-miR-485/RAPGEFL1 axis
A novel long noncoding RNA, PICSAR, promotes thyroid cancer progression through the hsa-miR-320A/hsa-miR-485/RAPGEFL1 axis Open
Background Among endocrine cancers, thyroid carcinoma (TC) is the most prevalent and ranks sixth in global mortality rates. Aberrant expression of long noncoding RNA (lncRNAs) is associated with the progression of various human cancers, in…
View article: Correction: Prediction of thyroid malignancy risk using clinical and ultrasonography features and a machine learning approach
Correction: Prediction of thyroid malignancy risk using clinical and ultrasonography features and a machine learning approach Open
View article: LINC00162 Silencing Enhances Sorafenib Sensitivity and Inhibits Thyroid Cancer Cells Progression through Modulation of MAPK Signaling and Apoptosis
LINC00162 Silencing Enhances Sorafenib Sensitivity and Inhibits Thyroid Cancer Cells Progression through Modulation of MAPK Signaling and Apoptosis Open
Many studies have reported aberrant expression of the lncRNAs and indicated their role in cancer progression and drug resistance across various cancers. In this study, we aimed to evaluate the effect of the LINC00162 lncRNA in the chemosen…
View article: Leptomeningeal Seeding of Pituitary Adenoma in a Young Lady With Neglected Gigantism: An Extremely Rare Case Report
Leptomeningeal Seeding of Pituitary Adenoma in a Young Lady With Neglected Gigantism: An Extremely Rare Case Report Open
Pituitary neuroendocrine tumors can sometimes present with leptomeningeal seeding at their initial diagnosis, emphasizing the need for thorough evaluation in cases of leptomeningeal involvement. Additionally, it is crucial for general phys…
View article: Staging of esophageal cancer using PET/MRI: a systematic review with head-to-head comparison
Staging of esophageal cancer using PET/MRI: a systematic review with head-to-head comparison Open
View article: Cytotoxic Effect of Aqueous Extract of Sweet Pomegranate Seed and Vitamin D on MCF-7 Human Breast Cancer and Human Fibroblast Cell Lines
Cytotoxic Effect of Aqueous Extract of Sweet Pomegranate Seed and Vitamin D on MCF-7 Human Breast Cancer and Human Fibroblast Cell Lines Open
Background: In recent years, scientists have focused on the use of natural ingredients, including herbal extracts, in the treatment of breast cancer. Objectives: This study aimed to evaluate the cytotoxic effects of the aqueous extract of …
View article: Safety and hemostatic effect of Achillea millefolium L. in localized bleeding.
Safety and hemostatic effect of Achillea millefolium L. in localized bleeding. Open
This study confirmed the hemostatic effect of hydroalcoholic extract of A. millefolium in localized bleeding and also the safety of this plant for topical usage.
View article: High-Energy Al@Cuo Thermite Fabricated by Core-Shell Route: Evaluation of Energy Release, Thermal Behavior, and Safety Parameters
High-Energy Al@Cuo Thermite Fabricated by Core-Shell Route: Evaluation of Energy Release, Thermal Behavior, and Safety Parameters Open
View article: Metastatic parathyroid carcinoma diagnosed after five surgical attempts: a case report and review of the literature
Metastatic parathyroid carcinoma diagnosed after five surgical attempts: a case report and review of the literature Open
Background Diagnosis of parathyroid carcinoma as a rare cause of primary hyperparathyroidism is usually very challenging, even after surgical resection. Case presentation A 45-year-old woman with a diagnosis of primary hyperparathyroidism …
View article: Unusual Presentation of Metastatic Medullary Thyroid Cancer Involving Bone Marrow, Kidneys, and Adrenal Gland: A Literature Review Based on a Case Report
Unusual Presentation of Metastatic Medullary Thyroid Cancer Involving Bone Marrow, Kidneys, and Adrenal Gland: A Literature Review Based on a Case Report Open
Background Medullary thyroid cancer (MTC) is one of the rare neuroendocrine malignancies. This cancer is hereditary in approximately 20% of cases. Although lymph node (LN) metastasis is prevalent in MTC, distant metastasis is not commonly …
View article: Clinical Perspectives on the Histomolecular Features of the Pancreatic Precursor Lesions: A Narrative Review
Clinical Perspectives on the Histomolecular Features of the Pancreatic Precursor Lesions: A Narrative Review Open
Pancreatic cancer (PC) is a lethal cancer with poor prognoses. Identifying and characterizing pancreatic cystic lesions (PCLs) in the early detection and follow-up plans is thought to help detect pancreatic malignancy. Besides, the molecul…
View article: The role of methylation quantification of circulating tumor DNA (ctDNA) as a diagnostic biomarker of Pheochromocytomas (PCCs) and Paragangliomas (PGLs)
The role of methylation quantification of circulating tumor DNA (ctDNA) as a diagnostic biomarker of Pheochromocytomas (PCCs) and Paragangliomas (PGLs) Open
View article: From balance to imbalance: disruption of plasma glutathione concentration in micropapillary thyroid carcinoma
From balance to imbalance: disruption of plasma glutathione concentration in micropapillary thyroid carcinoma Open
View article: Effects of Levothyroxine and Liothyronine on Cirrhotic Cardiomyopathy in Rats
Effects of Levothyroxine and Liothyronine on Cirrhotic Cardiomyopathy in Rats Open
In liver cirrhosis, there is low T3 syndrome associated with a decrease in total triiodothyronine (T3) and free T3 concentrations and cirrhotic cardiomyopathy (CCM) with chronotropic incompetence. Thus, we aimed to investigate the effects …
View article: Effects of Gap 26, a Connexin 43 Inhibitor, on Cirrhotic Cardiomyopathy in Rats
Effects of Gap 26, a Connexin 43 Inhibitor, on Cirrhotic Cardiomyopathy in Rats Open
View article: Empty sella in somatotropic pituitary adenomas; a series of 23 cases
Empty sella in somatotropic pituitary adenomas; a series of 23 cases Open
Purpose We aimed to investigate empty sella syndrome in somatotrophic pituitary adenoma for possible etiology, complications, and treatment options. Method Among over 2,000 skull base masses that have been managed in our center since 2013,…
View article: Circulating Tumor DNA (ctDNA) Methylation Quantification As Diagnostic Biomarker of Pheochromocytomas (PCCs) and Paragangliomas (PGLs)
Circulating Tumor DNA (ctDNA) Methylation Quantification As Diagnostic Biomarker of Pheochromocytomas (PCCs) and Paragangliomas (PGLs) Open
Introduction: Circulating tumor DNA (ctDNA) is newly diagnosed tumor DNA that can easily represent a tumor’s genetic and epigenetic change. Pheochromocytomas (PCCs) and Paragangliomas (PGLs) are rare tumors of adrenal gland tissue that hav…
View article: Single-cell transcriptome analysis for cancer and biology of the pancreas: A review on recent progress
Single-cell transcriptome analysis for cancer and biology of the pancreas: A review on recent progress Open
Single-cell sequencing has become one of the most used techniques across the wide field of biology. It has enabled researchers to investigate the whole transcriptome at the cellular level across tissues, which unlocks numerous potentials f…
View article: A Case Report of Cushing’s Disease Presenting With Psychosis and Muscle Weakness Postpartum
A Case Report of Cushing’s Disease Presenting With Psychosis and Muscle Weakness Postpartum Open
Cushing’s syndrome is a condition leading to overproducing of cortisol by the adrenal glands. If the pituitary gland overproduces cortisol, it is called Cushing’s disease. Cushing’s syndrome and even Cushing’s disease during and after preg…
View article: Effective connectivity in individuals with Alzheimer's disease and mild cognitive impairment: A systematic review
Effective connectivity in individuals with Alzheimer's disease and mild cognitive impairment: A systematic review Open
Background: Alzheimer's disease (AD) is the most common cause of dementia. Effective connectivity (EC) methods signify the direction of brain interactions. The identified inter-system mappings can be helpful in characterizing the pathophys…
View article: Sildenafil improves radiation‐induced oral mucositis by attenuating oxidative stress, NF‐κB, ERK and JNK signalling pathways
Sildenafil improves radiation‐induced oral mucositis by attenuating oxidative stress, NF‐κB, ERK and JNK signalling pathways Open
Radiation‐induced oral mucositis is a common and dose‐limiting complication of head and neck radiotherapy with no effective treatment. Previous studies revealed that sildenafil, a phosphodiesterase 5 inhibitor, has anti‐inflammatory and an…
View article: Medical management of pancreatic neuroendocrine tumors in patients with MEN 1: case report
Medical management of pancreatic neuroendocrine tumors in patients with MEN 1: case report Open
View article: Whole-organ decellularization of the human uterus and in vivo application of the bio-scaffolds in animal models
Whole-organ decellularization of the human uterus and in vivo application of the bio-scaffolds in animal models Open
View article: microRNAs and long non‐coding RNAs as biomarkers for polycystic ovary syndrome
microRNAs and long non‐coding RNAs as biomarkers for polycystic ovary syndrome Open
Polycystic ovary syndrome (PCOS) is known as the most common metabolic/endocrine disorder among women of reproductive age. Its complicated causality assessment and diagnostic emphasized the role of non‐coding regulatory RNAs as molecular b…
View article: Evidencing the presence of merkel cell polyomavirus in papillary thyroid cancer
Evidencing the presence of merkel cell polyomavirus in papillary thyroid cancer Open
Merkel cell polyomavirus (MCPyV) infects most people asymptomatically, but recent reports indicate that the virus may be related to carcinogenesis. This study aimed to evaluate the impact of MCPyV on the development of papillary thyroid ca…