Seyede Momeneh Mohammadi
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View article: Effects of statins on the incidence and outcomes of acute kidney injury in critically ill patients: a systematic review and meta-analysis
Effects of statins on the incidence and outcomes of acute kidney injury in critically ill patients: a systematic review and meta-analysis Open
Introduction In critically ill patients, acute kidney injury (AKI) is a common complication with the very high mortality rates. We aimed to analyzse whether pre- and perioperative statins might prevent AKI and improve overall prognosis in …
View article: Survival and prognostic factors among hospitalized pancreatic cancer patients in Northwestern Iran
Survival and prognostic factors among hospitalized pancreatic cancer patients in Northwestern Iran Open
Background: Pancreatic cancer (PC) is associated with a poor prognosis, with various modifiable risk factors affecting the survival of patients. Our aim was to evaluate the survival rate and the prognostic factors influencing survival in P…
View article: The ADAM17 Inhibition in Cord Blood Stem Cell Derived CD16 + NK Cells Enhanced Cytotoxicity against Acute Lymphoblastic Leukemia Cells
The ADAM17 Inhibition in Cord Blood Stem Cell Derived CD16 + NK Cells Enhanced Cytotoxicity against Acute Lymphoblastic Leukemia Cells Open
Background: Fortunately, ample efforts are attempting to find the best strategy to improve the NK cell anti-leukemia capacity in the treatment of different types of cancers. Despite the favorable ADCC capacity of functional CD16+ NK cells …
View article: A Systematic Review and Meta-Analysis on the Significance of TIGIT in Solid Cancers: Dual TIGIT/PD-1 Blockade to Overcome Immune-Resistance in Solid Cancers
A Systematic Review and Meta-Analysis on the Significance of TIGIT in Solid Cancers: Dual TIGIT/PD-1 Blockade to Overcome Immune-Resistance in Solid Cancers Open
Preclinical studies have indicated that T-cell immunoglobulin and ITIM domain (TIGIT) can substantially attenuate anti-tumoral immune responses. Although multiple clinical studies have evaluated the significance of TIGIT in patients with s…
View article: Improved COVID-19 ICU admission and mortality outcomes following treatment with statins: a systematic review and meta-analysis
Improved COVID-19 ICU admission and mortality outcomes following treatment with statins: a systematic review and meta-analysis Open
Introduction Approximately 1% of the world population has now been infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19). With cases still rising and vaccines just be…
View article: Improved COVID‐19 Outcomes following Statin Therapy: An Updated Systematic Review and Meta‐analysis
Improved COVID‐19 Outcomes following Statin Therapy: An Updated Systematic Review and Meta‐analysis Open
Background . Although vaccine rollout for COVID‐19 has been effective in some countries, there is still an urgent need to reduce disease transmission and severity. We recently carried out a meta‐analysis and found that pre‐ and in‐hospital…
View article: The Psychological Impact of COVID-19 Pandemic on Mental Health of Iranian Population
The Psychological Impact of COVID-19 Pandemic on Mental Health of Iranian Population Open
Introduction: As the coronavirus disease 2019 (COVID-19) pandemic rapidly sweeps across the world, it is inducing a considerable degree of psychological problems, which can affect everyone in the community. This study aimed to compare the …
View article: Low-Level Laser Irradiation Modulated Viability of Normal and Tumor Human Lymphocytes In Vitro
Low-Level Laser Irradiation Modulated Viability of Normal and Tumor Human Lymphocytes In Vitro Open
Introduction : Laser radiation is a promising strategy against various malignancies. Recent studies have shown that the application of low-power laser therapy (LPLT) at different doses and exposure times could modulate the growth dynamic o…
View article: Streptomyces Levis ABRIINW111 Inhibits SW480 Cells Growth by Apoptosis Induction
Streptomyces Levis ABRIINW111 Inhibits SW480 Cells Growth by Apoptosis Induction Open
Purpose: Streptomyces sp., a dominant genus in Actinomycetes, is the source of a wide variety of secondary metabolites. Microbial metabolites can be utilized as novel anticancer agents; with fewer side effects. The present article illustra…
View article: Culture filtrate ether extracted metabolites from Streptomyces levis ABRIINW111 increased apoptosis and reduced proliferation in acute lymphoblastic leukemia
Culture filtrate ether extracted metabolites from Streptomyces levis ABRIINW111 increased apoptosis and reduced proliferation in acute lymphoblastic leukemia Open
Despite the advances in the discovery of various types of anticancer drugs for curing acute lymphoblastic leukemia (ALL), their toxicity and unfavorable side effects remained as big limitations for therapeutical applications. In this regar…
View article: Extracted metabolite from <i>Streptomyces Levis</i> ABRIINW111 altered the gene expression in colon cancer.
Extracted metabolite from <i>Streptomyces Levis</i> ABRIINW111 altered the gene expression in colon cancer. Open
These findings indicate that ether extracted metabolites of Streptomyces Levis ABRIINW111 have anti-carcinogenic effects on colon cancer.
View article: Terminal Deoxynucleotidyl Transferase (TdT) Inhibition of Cord Blood Derived B and T Cells Expansion
Terminal Deoxynucleotidyl Transferase (TdT) Inhibition of Cord Blood Derived B and T Cells Expansion Open
Purpose: Terminal deoxynucleotidyl transferase(TdT) is a DNA polymerase that is present in immature pre-B and pre-T cells. TdT inserts N-nucleotides to the V (D) J gene segment during rearrangements of genes, therefore, it plays a vital ro…
View article: Cord Blood Cells Responses to IL2, IL7 and IL15 Cytokines for mTOR Expression
Cord Blood Cells Responses to IL2, IL7 and IL15 Cytokines for mTOR Expression Open
Purpose: Mammalian target of rapamycin (mTOR)is important in hematopoiesis and affect cell growth,differentiation and survival. Although previous studies were identified the effect of cytokines on the mononuclear cells development however …
View article: Impact of C-rel inhibition of cord blood-derived B-, T-, and NK cells
Impact of C-rel inhibition of cord blood-derived B-, T-, and NK cells Open
The c-Rel transcription factor is a unique member of the nuclear factor (NF)-κB family that has a role in curtailing the proliferation, differentiation, cytokine production, and overall activity of B- and T-cells. In addition, c-Rel is a k…
View article: Key Immune Cell Cytokines Affects the Telomere Activity of Cord Blood Cells In vitro
Key Immune Cell Cytokines Affects the Telomere Activity of Cord Blood Cells In vitro Open
Taken together, IL-7 and IL-15 increased telomere length and hTERT gene expression at 14 day of the experiment. In conclusion, it seems likely that cells maintain naïve phenotype due to prolonged exposure of IL-7 and IL-15.
View article: Cord Blood Mononuclear Cells Have a Potential to Produce NK Cells Using IL2Rg Cytokines
Cord Blood Mononuclear Cells Have a Potential to Produce NK Cells Using IL2Rg Cytokines Open
Purpose: Although bone marrow represents the main site for NK cell development and also distinct thymic-dependentNK cell pathway was identified, the cytokines effect on the NK cell generation from cord blood is unclear. Studies were identi…