Seyoung Mun
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View article: Divergent ancestry of Korean native and Thai poultry with independent gene pool retention in Korean commercial chickens
Divergent ancestry of Korean native and Thai poultry with independent gene pool retention in Korean commercial chickens Open
Clustering analysis revealed that KNC breeds formed a separate group from indigenous and local chickens and red junglefowl in Thailand. The distinct genetic patterns suggest independent evolution of the KNC and local Thai breeds, although …
View article: Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tissues
Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tissues Open
Epizootic shell disease (ESD) is characterized by shell erosion, pitting, and melanization in the American lobster ( Homarus americanus ) and is associated with a polymicrobial infection. The disease is multifactorial, with several contrib…
View article: Skin microbiome-biophysical association: a first integrative approach to classifying Korean skin types and aging groups
Skin microbiome-biophysical association: a first integrative approach to classifying Korean skin types and aging groups Open
Introduction The field of human microbiome research is rapidly expanding beyond the gut and into the facial skin care industry. However, there is still no established criterion to define the objective relationship between the microbiome an…
View article: Comparative Analysis of Bacteriome in Hair Follicle Layers of Patients with Female Pattern Androgenic Alopecia
Comparative Analysis of Bacteriome in Hair Follicle Layers of Patients with Female Pattern Androgenic Alopecia Open
Androgenetic alopecia (AGA) is the most common form of patterned hair loss, exhibiting gender-specific clinical features. Recent studies highlight the importance of the skin microbiome in maintaining skin health, but the relationship betwe…
View article: Shh agonist enhances maturation in homotypic Lgr5-positive inner ear organoids
Shh agonist enhances maturation in homotypic Lgr5-positive inner ear organoids Open
Background: The regeneration of functional hair cells (HCs) remains a critical challenge in addressing sensorineural hearing loss. This study aimed to investigate the molecular and functional mechanisms driving stereocilia maturation withi…
View article: Lonafarnib Protects Against Muscle Atrophy Induced by Dexamethasone
Lonafarnib Protects Against Muscle Atrophy Induced by Dexamethasone Open
Background Muscle atrophy, including glucocorticoid‐induced muscle wasting from treatments such as dexamethasone (DEX), results in significant reductions in muscle mass, strength and function. This study investigates the potential of lonaf…
View article: Complete genome sequence of <i>Weissella cibaria</i> strain CXO-01 isolated from Korean saliva
Complete genome sequence of <i>Weissella cibaria</i> strain CXO-01 isolated from Korean saliva Open
We present the genome sequence of Weissella cibaria strain CXO-01, isolated from saliva from one Korean individual and kimchi. The genome consisted of one circular chromosome with a length of 2,371,631 bp, three circular plasmids of 20,579…
View article: Investigation and validation of stereocilia development in homogenic cochlea progenitor cell organoid using bulk and single-cell RNA sequencing analysis
Investigation and validation of stereocilia development in homogenic cochlea progenitor cell organoid using bulk and single-cell RNA sequencing analysis Open
The hair cell (HC)s exhibit mechanoelectrical transduction that is enabled by stereocilia. Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is known to be involved in the generation of HCs. The stripping method is widely …
View article: Facial Skin Biophysical Multi-Parameter and Microbiome-Based Korean Skin Cutotype (KSC) Determination
Facial Skin Biophysical Multi-Parameter and Microbiome-Based Korean Skin Cutotype (KSC) Determination Open
The field of human microbiome research is rapidly expanding beyond the gut and into the facial skin care industry. However, there is still no established criterion to define the objective relationship between the microbiome and clinical tr…
View article: Dietary Bacillus spp. supplementation to both sow and progenies improved post-weaning growth rate, gut function, and reduce the pro-inflammatory cytokine production in weaners challenged with Escherichia coli K88
Dietary Bacillus spp. supplementation to both sow and progenies improved post-weaning growth rate, gut function, and reduce the pro-inflammatory cytokine production in weaners challenged with Escherichia coli K88 Open
Background The use of probiotics (PRO) in late gestation sow and their impact on progenies’ performance during the post-weaning stage has received more attention from the researchers recently. This study aimed to analyze the effect of prob…
View article: Human Endogenous Retrovirus-K (HML-2)-Related Genetic Variation: Human Genome Diversity and Disease
Human Endogenous Retrovirus-K (HML-2)-Related Genetic Variation: Human Genome Diversity and Disease Open
Human endogenous retroviruses (HERVs) comprise a significant portion of the human genome, making up roughly 8%, a notable comparison to the 2–3% represented by coding sequences. Numerous studies have underscored the critical role and impor…
View article: Marine-derived Ca-Mg complex influences lipid and glucose metabolism, serum metabolites, colostrum profile, and stress hormone in sows over four-parity periods
Marine-derived Ca-Mg complex influences lipid and glucose metabolism, serum metabolites, colostrum profile, and stress hormone in sows over four-parity periods Open
Minerals is required small amounts among various nutrients, but it has a significant impact on sow longevity and reproduction performance. This study was carried out to see the beneficial effects of marine-derived Ca-Mg complex on the repr…
View article: A Glance into the Destiny of Transcriptomic Activity, Embodied by the HOX Genes, in Neonatal and Aging Dermal Cells
A Glance into the Destiny of Transcriptomic Activity, Embodied by the HOX Genes, in Neonatal and Aging Dermal Cells Open
Skin is an organ having a crucial role in the protection of muscle, bone, and internal organs and undergoing continuous self-renewal and aged. The growing interest in the prevention of skin aging and rejuvenation has sparked a surge of ind…
View article: Carapace microbiota in American lobsters (Homarus americanus) associated with epizootic shell disease and the green gland
Carapace microbiota in American lobsters (Homarus americanus) associated with epizootic shell disease and the green gland Open
Epizootic Shell Disease (ESD) has posed a great threat, both ecologically and economically, to the American lobster population of Long Island Sound since its emergence in the late 1990s. Because of the polymicrobial nature of carapace infe…
View article: Genome-Wide Pathway Exploration of the Epidermidibacterium keratini EPI-7T
Genome-Wide Pathway Exploration of the Epidermidibacterium keratini EPI-7T Open
Functional cosmetics industries using skin microbiome screening and beneficial materials isolated from key microorganisms are receiving increasing attention. Since Epidermidibacterium keratini EPI-7T was first discovered in human skin, pre…
View article: Understanding the bacterial compositional network associations between oral and gut microbiome within healthy Koreans
Understanding the bacterial compositional network associations between oral and gut microbiome within healthy Koreans Open
Oral microbial ecosystem could influence intestinal diseases, but there have been insufficient studies demonstrating the association of microbial composition between the oral cavity and the intestinal system. Thus, we aimed to investigate …
View article: Efficacy and Safety of Epidermidibacterium Keratini EPI-7 Derived Postbiotics in Skin Aging: A Prospective Clinical Study
Efficacy and Safety of Epidermidibacterium Keratini EPI-7 Derived Postbiotics in Skin Aging: A Prospective Clinical Study Open
The present study investigated the effect of topical application of Epidermidibacterium Keratini (EPI-7) ferment filtrate, which is a postbiotic product of a novel actinobacteria, on skin aging, by performing a prospective randomized split…
View article: Tributyrin and anise mixture supplementation improves growth performance, nutrient digestibility, jejunal villus height, and fecal microbiota in weaned pigs
Tributyrin and anise mixture supplementation improves growth performance, nutrient digestibility, jejunal villus height, and fecal microbiota in weaned pigs Open
Introduction The objective of this study was to investigate the effects of dietary supplementation of tributyrin and anise mixture (TA) on growth performance, apparent nutrient digestibility, fecal noxious gas emission, fecal score, jejuna…
View article: Nourishing neonatal piglets with synthetic milk and Lactobacillus sp. at birth highly modifies the gut microbial communities at the post-weaning stage
Nourishing neonatal piglets with synthetic milk and Lactobacillus sp. at birth highly modifies the gut microbial communities at the post-weaning stage Open
The importance of probiotics in pig production is widely recognized. However, the precise role of probiotics in regulating the gut microbiota of piglets has not been assessed extensively. Therefore, we intend to examine whether suckling pi…
View article: Dermatobacter hominis gen. nov., sp. nov., a new member of the family Iamiaceae, isolated from keratin epidermis
Dermatobacter hominis gen. nov., sp. nov., a new member of the family Iamiaceae, isolated from keratin epidermis Open
A non-motile, novel actinobacterial strain, designated Kera-3 T , was isolated on 1/10 diluted R2A agar from human keratinocytes. Strain Kera-3 T was Gram-stain-positive, aerobic and rod-shaped. The whole-cell hydrolysis of amino acids con…
View article: Supplementation of carbohydrate enzymes plus protease to the diet of finishing pigs containing 2 protein levels on the effects of growth performance, toxic gas emissions, meat quality, and colonic microbiota community
Supplementation of carbohydrate enzymes plus protease to the diet of finishing pigs containing 2 protein levels on the effects of growth performance, toxic gas emissions, meat quality, and colonic microbiota community Open
Background Dietary supplementation with exogenous enzymes may positively affect the traits of finishing pigs. The present study investigated the effects of different protein levels and exogenous carbohydrate enzymes plus protease on growth…
View article: Human Retrotransposons and Effective Computational Detection Methods for Next-Generation Sequencing Data
Human Retrotransposons and Effective Computational Detection Methods for Next-Generation Sequencing Data Open
Transposable elements (TEs) are classified into two classes according to their mobilization mechanism. Compared to DNA transposons that move by the “cut and paste” mechanism, retrotransposons mobilize via the “copy and paste” method. They …
View article: The Time Sequence of Gene Expression Changes after Spinal Cord Injury
The Time Sequence of Gene Expression Changes after Spinal Cord Injury Open
Gene expression changes following spinal cord injury (SCI) are time-dependent, and an accurate understanding of these changes can be crucial in determining time-based treatment options in a clinical setting. We performed RNA sequencing of …
View article: Identification of Potentially Pathogenic Variants Associated with Recurrence in Medication-Related Osteonecrosis of the Jaw (MRONJ) Patients Using Whole-Exome Sequencing
Identification of Potentially Pathogenic Variants Associated with Recurrence in Medication-Related Osteonecrosis of the Jaw (MRONJ) Patients Using Whole-Exome Sequencing Open
Background: Bisphosphonates are antiresorptive and antiangiogenic drugs that prevent and treat bone loss and mineralization in women with postmenopausal osteoporosis and cancer patients. Medication-related osteonecrosis of the jaw (MRONJ) …
View article: Transcriptome Profile of Membrane and Extracellular Matrix Components in Ligament-Fibroblastic Progenitors and Cementoblasts Differentiated from Human Periodontal Ligament Cells
Transcriptome Profile of Membrane and Extracellular Matrix Components in Ligament-Fibroblastic Progenitors and Cementoblasts Differentiated from Human Periodontal Ligament Cells Open
Ligament-fibroblastic cells and cementoblasts, two types of progenitor cells that differentiate from periodontal ligament stem cells (hPDLSCs), are responsible for the formation of the adhesive tissues in the tooth root. Since one of the f…
View article: A qRT-PCR Method Capable of Quantifying Specific Microorganisms Compared to NGS-Based Metagenome Profiling Data
A qRT-PCR Method Capable of Quantifying Specific Microorganisms Compared to NGS-Based Metagenome Profiling Data Open
Metagenome profiling research using next-generation sequencing (NGS), a technique widely used to analyze the diversity and composition of microorganisms living in the human body, especially the gastrointestinal tract, has been actively con…