Lisha Sun
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View article: The role of immune cells-mediated memory in weight cycling, glucose disorders and insulin resistance
The role of immune cells-mediated memory in weight cycling, glucose disorders and insulin resistance Open
Weight cycling (WC), defined as the repeated process of weight gain and loss, is one of the biggest challenges in the management of weight. It is estimated that the majority of individuals (60%) will regain their lost weight within a few y…
View article: Mutational Landscape of Ameloblastoma: Analysis of <scp> <i>BRAF</i> </scp> and Other Key Mutations in Chinese Patients
Mutational Landscape of Ameloblastoma: Analysis of <span> <i>BRAF</i> </span> and Other Key Mutations in Chinese Patients Open
Objectives To investigate the prevalence of BRAF , SMO , KRAS , HRAS , NRAS , FGRF2 , and CTNNB1 gene mutations in Chinese ameloblastoma (AM) patients and explore their associations with clinical characteristics. Materials and Methods DNA …
View article: Clinical Characteristics and Prognostic Factors of 199 Salivary Acinic Cell Carcinoma
Clinical Characteristics and Prognostic Factors of 199 Salivary Acinic Cell Carcinoma Open
Objects This retrospective study aimed to investigate the clinical characteristics and prognostic features of acinic cell carcinoma (AciCC) of the salivary gland. Methods One Hundred Ninety‐nine cases of AciCC were retrospectively reviewed…
View article: Identification of Novel and Rare <scp> <i>GNAS</i> </scp> Mutations in Craniofacial Fibrous Dysplasia
Identification of Novel and Rare <span> <i>GNAS</i> </span> Mutations in Craniofacial Fibrous Dysplasia Open
Background Fibrous dysplasia (FD), caused by activating mutations of GNAS , is a skeletal disorder with considerable clinicopathological heterogeneity. Although prevalent mutations such as R201C and R201H dominate in FD, a limited number o…
View article: Deciphering odontogenic myxoma: the role of copy number variations as diagnostic signatures
Deciphering odontogenic myxoma: the role of copy number variations as diagnostic signatures Open
In light of the lack of reliable molecular markers for odontogenic myxoma (OM), the detection of copy number variation (CNV) may present a more objective method for assessing ambiguous cases. In this study, we employed multiregional microd…
View article: The prevalence, diagnostic accuracy and genotype-phenotype correlation of GNAS mutations in fibrous dysplasia: a meta-analysis
The prevalence, diagnostic accuracy and genotype-phenotype correlation of GNAS mutations in fibrous dysplasia: a meta-analysis Open
Background There is inconsistent evidence regarding the accuracy of GNAS mutations identification for the diagnosis of FD/MAS. This study was performed to estimate the prevalence and diagnostic accuracy of GNAS mutations detection and to p…
View article: Carrier-free delivery of nucleic acid and photosensitizer nanoparticles for enhanced photodynamic and gene antitumour therapy
Carrier-free delivery of nucleic acid and photosensitizer nanoparticles for enhanced photodynamic and gene antitumour therapy Open
Activated anti-oxidation reactions in cells partially diminish the anticancer effect of photodynamic therapy (PDT), significantly hindering efforts to increase the efficacy of PDT. The expression of transcription factor E2 related factor 2…
View article: The anterior lobe of the parotid gland: a CT sialographic study
The anterior lobe of the parotid gland: a CT sialographic study Open
Objectives To investigate the imaging and anatomic features of the anterior lobe (AL) of the superficial parotid gland (SPG). Methods Computed tomographic sialography examinations were undertaken for 142 parotid glands in 77 patients. Whol…
View article: A hybrid feature selection algorithm combining information gain and grouping particle swarm optimization for cancer diagnosis
A hybrid feature selection algorithm combining information gain and grouping particle swarm optimization for cancer diagnosis Open
Background Cancer diagnosis based on machine learning has become a popular application direction. Support vector machine (SVM), as a classical machine learning algorithm, has been widely used in cancer diagnosis because of its advantages i…
View article: Can botulinum toxin injection alleviate the pain of bruxism? A Bayesian network analysis and a single-arm analysis
Can botulinum toxin injection alleviate the pain of bruxism? A Bayesian network analysis and a single-arm analysis Open
BTA significantly relieves the pain of bruxism for 6 months after injection, and its therapeutic efficacy was higher than that of oral splinting. Nevertheless, further long-term follow-up randomized controlled trials comparing BTA with oth…
View article: Effect of Bifidobacterium on osteoclasts: TNF-α/NF-κB inflammatory signal pathway-mediated mechanism
Effect of Bifidobacterium on osteoclasts: TNF-α/NF-κB inflammatory signal pathway-mediated mechanism Open
Osteoporosis is a systemic multifactorial bone disease characterized by low bone quality and density and bone microstructure damage, increasing bone fragility and fracture vulnerability. Increased osteoclast differentiation and activity ar…
View article: MiR-95-3p acts as a prognostic marker and promotes cervical cancer progression by targeting VCAM1
MiR-95-3p acts as a prognostic marker and promotes cervical cancer progression by targeting VCAM1 Open
Our study was the first to show that miR-95-3p could serve as a prognostic biomarker of cervical cancer. Mechanistically, we discovered that miR-95-3p inhibited the expression of the cell adhesion molecule VCAM1 and thus promoted further t…
View article: The landscape and prognostic value of immune characteristics in uterine corpus endometrial cancer
The landscape and prognostic value of immune characteristics in uterine corpus endometrial cancer Open
In the present study, we explored the clinical and immunological characteristics of 575 uterine corpus endometrial carcinoma (UCEC) samples obtained from The Cancer Genome Atlas (TCGA) using the ESTIMATE and CIBERSORT algorithms. First, Ka…
View article: Increased Cerebrospinal Fluid Uric Acid Levels in Guillain–Barré Syndrome
Increased Cerebrospinal Fluid Uric Acid Levels in Guillain–Barré Syndrome Open
Uric acid (UA) is a natural scavenger for peroxynitrite and can reflect antioxidant activity and oxidative stress in several neurological disorders. Changes in serum and cerebrospinal fluid (CSF) levels of UA have been reported in patients…
View article: [Parotid CT imaging reporting and data system: A preliminary study].
[Parotid CT imaging reporting and data system: A preliminary study]. Open
PI-RADS can be used to evaluate the risk of malignancy and will be helpful to improve the imaging diagnosis and clinical treatment of parotid gland neoplasms.
View article: <p>miR-762 Promotes Malignant Development of Head and Neck Squamous Cell Carcinoma by Targeting PHLPP2 and FOXO4</p>
miR-762 Promotes Malignant Development of Head and Neck Squamous Cell Carcinoma by Targeting PHLPP2 and FOXO4 Open
miR-762 promotes HNSCC progression by targeting PHLPP2 and FOXO4. Therefore, miR-762 might be a potential diagnostic or therapeutic target for HNSCC.
View article: Issue Information
Issue Information Open
Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have f…
View article: Nomogram for prediction of level 2 axillary lymph node metastasis in proven level 1 node-positive breast cancer patients
Nomogram for prediction of level 2 axillary lymph node metastasis in proven level 1 node-positive breast cancer patients Open
Our nomogram could help predict L-2-ALNM in patients with level 1 axillary lymph node metastasis. Patients with a low probability of L-2-ALNM could be spared level 2 axillary lymph node dissection, thereby reducing postoperative morbidity.
View article: Expression of vascular endothelial growth factor and caspase-3 in mucinous breast carcinoma and infiltrating ductal carcinoma-not otherwise specified, and the correlation with disease-free survival
Expression of vascular endothelial growth factor and caspase-3 in mucinous breast carcinoma and infiltrating ductal carcinoma-not otherwise specified, and the correlation with disease-free survival Open
Mucinous breast carcinoma (MBC) is a rare type of breast cancer, but it has been infrequently studied due to its associated good prognosis. Vascular endothelial growth factor (VEGF) and caspase-3 have been identified to be prognostic facto…
View article: Clinical significance of MSKCC nomogram on guiding the application of touch imprint cytology and frozen section in intraoperative assessment of breast sentinel lymph nodes
Clinical significance of MSKCC nomogram on guiding the application of touch imprint cytology and frozen section in intraoperative assessment of breast sentinel lymph nodes Open
The widely practiced intra-operative methods for rapid evaluation and detection of sentinel lymph node (SLN) status include frozen section (FS) and touch imprint cytology (TIC). This study optimized the use of TIC and FS in the intra-opera…