Shabnam Heydarzadeh
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View article: Endocrine polyautoimmunity: Mechanistic insights and the future of AI-driven diagnostics
Endocrine polyautoimmunity: Mechanistic insights and the future of AI-driven diagnostics Open
The most prevalent form of polyautoimmunity is autoimmune thyroid diseases (AITD), which frequently coexist with other autoimmune disorders and often act as a central conductor in the symphony of autoimmunity. Due to overlapping clinical m…
View article: Regulation of iodide transportation by a plant secondary metabolite in SW1736 anaplastic thyroid cancer cell line
Regulation of iodide transportation by a plant secondary metabolite in SW1736 anaplastic thyroid cancer cell line Open
The expression of NIS and subsequent iodine uptake after Genistein treatment suggest that ATC cells may be becoming more like differentiated thyroid cells, which typically have higher iodine uptake capabilities. However, this redifferentia…
View article: A novel approach to regulate glucose uptake in an anaplastic thyroid cancer cell line
A novel approach to regulate glucose uptake in an anaplastic thyroid cancer cell line Open
Aims and background Curcumin’s function in affecting cancer metabolic reprogramming remains poorly understood. Herein, we aimed to elucidate a novel link between curcumin and the glucose uptake metabolism and the status of glucose transpor…
View article: Thyroid Function in the Time of COVID-19: A Systematic Review of Disease Progression and Vaccination Effect
Thyroid Function in the Time of COVID-19: A Systematic Review of Disease Progression and Vaccination Effect Open
Objectives: This systematic review sought to address three key questions: (1) what differences in abnormal thyroid function test results are observed between COVID-19 patients and healthy individuals? (2) How does the severity of COVID-19 …
View article: Review of: "Reduced Blood to Brain Glucose Transport as The Cause For Hyperglycemia: a Model That Resolves Multiple Anomalies in Type 2 Diabetes"
Review of: "Reduced Blood to Brain Glucose Transport as The Cause For Hyperglycemia: a Model That Resolves Multiple Anomalies in Type 2 Diabetes" Open
View article: RET Proto-Oncogene Mutations: Impact on Diagnosis, Treatment and Prognosis of MTC
RET Proto-Oncogene Mutations: Impact on Diagnosis, Treatment and Prognosis of MTC Open
Variants of MTC result from different mutations in exons of the RET gene. RET proto-oncogene is activated by a DNA rearrangement and it is one of the first tyrosine kinase receptor (RTK) proteins found to play a role in neoplasia. Early de…
View article: Recent Developments in Cell Line Shipping Methods: Pivotal Gaps in Cellular Death Sciences
Recent Developments in Cell Line Shipping Methods: Pivotal Gaps in Cellular Death Sciences Open
Contrary to remarkable advances within the cell therapy industry, scientists expose dissatisfied challenges associated with the preservation and post-thaw cell death globally. Post cryopreservation apoptosis is normally observed in culture…
View article: CpG island status as an epigenetic alteration for NIS promoter in thyroid neoplasms; a cross-sectional study with a systematic review
CpG island status as an epigenetic alteration for NIS promoter in thyroid neoplasms; a cross-sectional study with a systematic review Open
View article: TIMP3 Gene Upstream CpG Island Methylation is Associated with BRAF V600E Mutation in Thyroid Neoplasms
TIMP3 Gene Upstream CpG Island Methylation is Associated with BRAF V600E Mutation in Thyroid Neoplasms Open
Aims: Extensive evidence demonstrated that epigenetic modifications play a crucial role in the development of thyroid malignancies. The onset of DNA methylation sequencing technologies has provided a more comprehensive understanding of bio…
View article: CpG island status as an epigenetic alteration for NIS promoter in thyroid neoplasms; a cross- sectional study with a systematic review
CpG island status as an epigenetic alteration for NIS promoter in thyroid neoplasms; a cross- sectional study with a systematic review Open
Background Gene silence via methylation of the CpG island is the most common epigenetic modification in cancer. Aberrant DNA methylation interferes with active transcription and is also significantly associated with poor tumor differentiat…
View article: Molecular Mechanisms of Glucose Uptake Regulation in Thyroid Cancer
Molecular Mechanisms of Glucose Uptake Regulation in Thyroid Cancer Open
Common capabilities of thyroid malignant cells are accelerating metabolism and increasing glucose uptake to optimize energy supply for growth. In tumor cells, keeping the power load required for cell survival is essential and glucose trans…
View article: Correction to: Regulators of glucose uptake in thyroid cancer cell lines
Correction to: Regulators of glucose uptake in thyroid cancer cell lines Open
View article: The Cross‐Talk between Polyphenols and the Target Enzymes Related to Oxidative Stress‐Induced Thyroid Cancer
The Cross‐Talk between Polyphenols and the Target Enzymes Related to Oxidative Stress‐Induced Thyroid Cancer Open
The most serious hallmark step of carcinogenesis is oxidative stress, which induces cell DNA damage. Although in normal conditions ROS are important second messengers, in pathological conditions such as cancer, due to imbalanced redox enzy…
View article: Chemoprotective and chemosensitizing effects of apigenin on cancer therapy
Chemoprotective and chemosensitizing effects of apigenin on cancer therapy Open
View article: Regulators of glucose uptake in thyroid cancer cell lines
Regulators of glucose uptake in thyroid cancer cell lines Open
Thyroid cancer is the most common sort of endocrine-related cancer with more prevalent in women and elderly individuals which has quickly widespread expansion in worldwide over the recent decades. Common features of malignant thyroid cells…
View article: Evaluation of Reciprocal Pharmaceutical Effects and Antibacterial Activity of Silver Nanoparticles and Methanolic Extract of Crocus sativus L. (Saffron) on Some Bacterial Strains
Evaluation of Reciprocal Pharmaceutical Effects and Antibacterial Activity of Silver Nanoparticles and Methanolic Extract of Crocus sativus L. (Saffron) on Some Bacterial Strains Open
Background: Silver nanoparticles (Ag-NPs) are the most prominent nanoparticles which are recognized for their high antimicrobial efficacy.\n Objectives: The aim of this study was to evaluate the reciprocal pharmaceutical effects and antiba…