Scott Sommerville
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View article: Unique Treatment of Atrial Fibrillation: Simultaneous Dual Direct-Current Cardioversion in Morbidly Obese Patients
Unique Treatment of Atrial Fibrillation: Simultaneous Dual Direct-Current Cardioversion in Morbidly Obese Patients Open
Atrial fibrillation (AFib) is a prevalent arrhythmia associated with substantial health complications and economic strain on the health care system in the United States. Obesity is a challenging comorbidity to manage in this scenario, as t…
View article: Biomechanical analysis of ridged dorsal wrist backslabs
Biomechanical analysis of ridged dorsal wrist backslabs Open
View article: High accuracy of positioning custom triflange acetabular components in tumour and total hip arthroplasty revision surgery
High accuracy of positioning custom triflange acetabular components in tumour and total hip arthroplasty revision surgery Open
Aims Custom triflange acetabular components (CTACs) play an important role in reconstructive orthopaedic surgery, particularly in revision total hip arthroplasty (rTHA) and pelvic tumour resection procedures. Accurate CTAC positioning is e…
View article: Biomechanical Analysis of Ridged Dorsal Wrist Backslabs
Biomechanical Analysis of Ridged Dorsal Wrist Backslabs Open
View article: What Factors Are Associated With Stem Breakage in Distal Femoral Endoprosthetic Replacements Undertaken for Primary Bone Tumors?
What Factors Are Associated With Stem Breakage in Distal Femoral Endoprosthetic Replacements Undertaken for Primary Bone Tumors? Open
Background The advantages of distal femoral replacement prostheses for reconstructions after tumors are well known; one such implant, the Global Modular Replacement System (GMRS), has been widely used since 2003. Although implant breakage …
View article: Supplementary Figure 2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
Supplementary Figure 2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases Open
Supplementary Figure 2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
View article: Supplementary Methods, Figure Legends 1-2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
Supplementary Methods, Figure Legends 1-2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases Open
Supplementary Methods, Figure Legends 1-2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
View article: Supplementary Figure 1 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
Supplementary Figure 1 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases Open
Supplementary Figure 1 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
View article: Supplementary Table 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
Supplementary Table 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation Open
Supplementary Table 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
View article: Supplementary Figure 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
Supplementary Figure 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation Open
Supplementary Figure 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
View article: Supplementary Table 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
Supplementary Table 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation Open
Supplementary Table 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
View article: Data from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
Data from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases Open
We conducted a transcriptomic screen of osteosarcoma (OS) biopsies and found that expression of osteoclast-specific tartrate-resistant acid phosphatase 5 (ACP5/TRAP) is significantly downregulated in OS compared with nonmalignant bo…
View article: Supplementary Figure 2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
Supplementary Figure 2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases Open
Supplementary Figure 2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
View article: Supplementary Figure 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
Supplementary Figure 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation Open
Supplementary Figure 1 from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
View article: Data from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
Data from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation Open
The E2F family of transcription factors plays a crucial role in the regulation of genes involved in cell proliferation, differentiation, and apoptosis. In keratinocytes, the inhibition of E2F is a key step in the control and initiation of …
View article: Supplementary Methods, Figure Legends 1-2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
Supplementary Methods, Figure Legends 1-2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases Open
Supplementary Methods, Figure Legends 1-2 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
View article: Supplementary Figure 1 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
Supplementary Figure 1 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases Open
Supplementary Figure 1 from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
View article: Data from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
Data from Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases Open
We conducted a transcriptomic screen of osteosarcoma (OS) biopsies and found that expression of osteoclast-specific tartrate-resistant acid phosphatase 5 (ACP5/TRAP) is significantly downregulated in OS compared with nonmalignant bo…
View article: Data from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation
Data from E2F7 Can Regulate Proliferation, Differentiation, and Apoptotic Responses in Human Keratinocytes: Implications for Cutaneous Squamous Cell Carcinoma Formation Open
The E2F family of transcription factors plays a crucial role in the regulation of genes involved in cell proliferation, differentiation, and apoptosis. In keratinocytes, the inhibition of E2F is a key step in the control and initiation of …
View article: Is an Acetabular Cage and Cement Fixation Sufficiently Durable for the Treatment of Destructive Acetabular Metastases?
Is an Acetabular Cage and Cement Fixation Sufficiently Durable for the Treatment of Destructive Acetabular Metastases? Open
Background Destructive bony acetabular metastases cause pain, pathological fractures, and loss of mobility. Although multiple fixation options are available, we have favored a rigid stainless steel partial pelvic cage for acetabular fixati…
View article: Expanding the Spectrum of Intraosseous Rhabdomyosarcoma
Expanding the Spectrum of Intraosseous Rhabdomyosarcoma Open
Primary intraosseous rhabdomyosarcomas (RMSs) are extremely rare. Recently 2 studies reported 4 cases of primary intraosseous RMS with EWSR1/FUS-TFCP2 gene fusions, associated with somewhat conflicting histologic features, ranging from spi…
View article: The impact of preexisting disease on outcomes of simple orthopaedic trauma: A prospective cohort study
The impact of preexisting disease on outcomes of simple orthopaedic trauma: A prospective cohort study Open
Background: This article describes a prospective cohort study trial which aims to determine what risk factors might be associated with increased levels of pain, disability and psychological distress following simple orthopaedic trauma. Met…
View article: Novel MEIS1-NCOA2 Gene Fusions Define a Distinct Primitive Spindle Cell Sarcoma of the Kidney
Novel MEIS1-NCOA2 Gene Fusions Define a Distinct Primitive Spindle Cell Sarcoma of the Kidney Open
We describe 2 cases of a distinct sarcoma characterized by a novel MEIS1-NCOA2 gene fusion. This gene fusion was identified in the renal neoplasms of 2 adults (21-y-old male, 72-y-old female). Histologically, the resected renal neoplasms h…