Shahid Ud Din Wani
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View article: Biosynthesized zinc oxide nanoparticles from halophilic soil extracts exhibiting antioxidant and antibacterial activities
Biosynthesized zinc oxide nanoparticles from halophilic soil extracts exhibiting antioxidant and antibacterial activities Open
Finding sustainable ways to synthesize nanomaterials has become more important as worries about human health, environmental pollution, and climate change have grown. Because of its numerous biomedical uses, especially as antibacterial and …
View article: Nanocarriers for Delivery of Anticancer Drugs: Current Developments, Challenges, and Perspectives
Nanocarriers for Delivery of Anticancer Drugs: Current Developments, Challenges, and Perspectives Open
Cancer, the most common condition worldwide, ranks second in terms of the number of human deaths, surpassing cardiovascular diseases. Uncontrolled cell multiplication and resistance to cell death are the traditional features of cancer. The…
View article: Divine noni's protective impact on Swiss albino mice's short-term memory impairment caused by cyclophosphamide: A behavioral and biochemical approach
Divine noni's protective impact on Swiss albino mice's short-term memory impairment caused by cyclophosphamide: A behavioral and biochemical approach Open
Cyclophosphamide (CYL) is a first-line cancer chemotherapeutic agent widely used for the treatment of cancer that has severe toxic effects. The primary mechanism by which CYL induces toxicity through free radical generation. Morinda citrif…
View article: Novel microwave-based green approach for the synthesis of dual-loaded cyclodextrin nanosponges: Characterization, pharmacodynamics, and pharmacokinetics evaluation
Novel microwave-based green approach for the synthesis of dual-loaded cyclodextrin nanosponges: Characterization, pharmacodynamics, and pharmacokinetics evaluation Open
Recently, microwave-based cyclodextrin nanosponges (CDNS) of domperidone (DOM) for their solubility and dissolution improvement have been studied. However, microwave-based CDNS for the dual-loading of cinnarizine (CIN) and DOM have not bee…
View article: Evaluation of Antidepressant Activity of Capsaicin Nanoemulsion in Nicotine Withdrawal-Induced Depression in Mice
Evaluation of Antidepressant Activity of Capsaicin Nanoemulsion in Nicotine Withdrawal-Induced Depression in Mice Open
Depression is a low-energy condition that has an impact on a person’s thoughts, actions, propensities, emotional state, and sense of wellbeing. According to the World Health Organization (WHO), 5% of adults are depressed. Individuals who a…
View article: A review on linking stress, depression, and insulin resistance via low-grade chronic inflammation
A review on linking stress, depression, and insulin resistance via low-grade chronic inflammation Open
Stress is a disturbance in homeostasis caused by psychological, physiological, or environmental factors. Prolonged reactions to chronic stress can be detrimental, resulting in various metabolic abnormalities, referred to as metabolic syndr…
View article: Nanoemulsion-based piperine to enhance bioavailability for the treatment of LPS-induced depression-like behaviour in mice
Nanoemulsion-based piperine to enhance bioavailability for the treatment of LPS-induced depression-like behaviour in mice Open
In the present study, the objective was to encapsulate piperine in nanoform by solvent evaporation method and to investigate the antidepressant-like activity of nanopiperine in lipopolysaccharide (LPS) induced depression in mice. LPS-induc…
View article: Physicochemical characterization, phytochemical analysis, and pharmacological evaluation of Sambucus wightiana
Physicochemical characterization, phytochemical analysis, and pharmacological evaluation of Sambucus wightiana Open
Sambucus wightiana (SW) is a 4–5-foot herbaceous stem with 5–9 leaflets and pinnatifid leaves (15–30 cm). It is used to treat stomach disorders, as an emetic for expelling poisonous substances, and as a laxative for controlling skin diseas…
View article: Optimisation of a Greener-Approach for the Synthesis of Cyclodextrin-Based Nanosponges for the Solubility Enhancement of Domperidone, a BCS Class II Drug
Optimisation of a Greener-Approach for the Synthesis of Cyclodextrin-Based Nanosponges for the Solubility Enhancement of Domperidone, a BCS Class II Drug Open
BCS class II molecules suffer from low oral bioavailability because of their poor permeability and sub-optimal aqueous solubility. One of the approaches to enhance their bioavailability is using cyclodextrin-based nanosponges. This study a…
View article: Current status of artificial intelligence in cancer management: emerging trends, limitations and future outlook
Current status of artificial intelligence in cancer management: emerging trends, limitations and future outlook Open
Artificial intelligence (AI) has been abetted in the progression of health care research including cancer research. Simultaneously, in this review, we anticipate the future outlook of AI. AI can adjust the usage of anticancer drugs and als…
View article: Prevalence of Cognitive Decline in Type 2 Diabetes Mellitus Patients: A Real-World Cross-Sectional Study in Mysuru, India
Prevalence of Cognitive Decline in Type 2 Diabetes Mellitus Patients: A Real-World Cross-Sectional Study in Mysuru, India Open
The goal of this research is to study the prevalence of cognitive impairment in diabetes mellitus (DM) patients and establish the necessity of detecting and treating it early in these patients. A cross-sectional study was conducted at a te…
View article: RP-HPLC-Based Bioanalytical Approach for Simultaneous Quantitation of Cinnarizine and Domperidone in Rat Plasma
RP-HPLC-Based Bioanalytical Approach for Simultaneous Quantitation of Cinnarizine and Domperidone in Rat Plasma Open
An accurate, precise and sensitive reverse-phase high-performance liquid chromatography (RP-HPLC) bioanalytical approach was developed for the simultaneous estimation of cinnarizine (CIN) and domperidone (DOM) in rat plasma using irbesarta…
View article: Omega-3 Fatty Acids Supplementation in the Treatment of Depression: An Observational Study
Omega-3 Fatty Acids Supplementation in the Treatment of Depression: An Observational Study Open
Depression is a common mood disorder characterized by persistent sadness and loss of interest. Research suggests an association between the inclusion of omega-3 fatty acids in the diet and a reduced risk for depression. The present study e…
View article: Promising Role of Silk-Based Biomaterials for Ocular-Based Drug Delivery and Tissue Engineering
Promising Role of Silk-Based Biomaterials for Ocular-Based Drug Delivery and Tissue Engineering Open
Silk is a wonderful biopolymer that has a long history of medical applications. Surgical cords and medically authorised human analogues made of silk have a long history of use in management. We describe the use of silk in the treatment of …
View article: Silk Fibroin as an Efficient Biomaterial for Drug Delivery, Gene Therapy, and Wound Healing
Silk Fibroin as an Efficient Biomaterial for Drug Delivery, Gene Therapy, and Wound Healing Open
Silk fibroin (SF), an organic material obtained from the cocoons of a silkworm Bombyx mori, is used in several applications and has a proven track record in biomedicine owing to its superior compatibility with the human body, superb mechan…
View article: GC-MS Analysis, Phytochemical Screening, and Antibacterial Activity of Cerana indica Propolis from Kashmir Region
GC-MS Analysis, Phytochemical Screening, and Antibacterial Activity of Cerana indica Propolis from Kashmir Region Open
Propolis is a resinous compound produced by honey bees. It contains bioactive molecules that possess a wide range of biological functions. The chemical composition of propolis is affected by various variables, including the vegetation, the…
View article: Evaluation of the Safety and Efficacy of Ormeloxifene, a Selective Estrogen Receptor Modulator and Medroxyprogesterone Acetate in Women with Non-Structural Abnormal Uterine Bleeding: A Randomized Clinical Trial
Evaluation of the Safety and Efficacy of Ormeloxifene, a Selective Estrogen Receptor Modulator and Medroxyprogesterone Acetate in Women with Non-Structural Abnormal Uterine Bleeding: A Randomized Clinical Trial Open
Background and objectives: Abnormal uterine bleeding is a significant clinical and gynaecological concern that necessitates its safe and effective treatment. The present study aims to compare the cost-effectiveness, safety, efficacy, and h…
View article: Analysis of Antidepressants Utilization for Patients Visiting Psychiatric Out-Patient Clinic in a Tertiary Care Hospital
Analysis of Antidepressants Utilization for Patients Visiting Psychiatric Out-Patient Clinic in a Tertiary Care Hospital Open
Depression is a prevalent mental health condition treated with antidepressants and other psychotropic medications. This study aimed to assess the utilization pattern of antidepressants among patients visiting the outpatient clinic of the p…
View article: Phytochemical Profiling and Antibacterial Activity of Methanol Leaf Extract of Skimmia anquetilia
Phytochemical Profiling and Antibacterial Activity of Methanol Leaf Extract of Skimmia anquetilia Open
Skimmia anquetilia is a plant species native to the Western Himalaya region that has tremendous potential for phytochemical activities. This study aimed to identify bioactive compounds and assess the antibacterial activity of S. anquetilia…
View article: Utilization of Artificial Intelligence in Disease Prevention: Diagnosis, Treatment, and Implications for the Healthcare Workforce
Utilization of Artificial Intelligence in Disease Prevention: Diagnosis, Treatment, and Implications for the Healthcare Workforce Open
Artificial intelligence (AI) has been described as one of the extremely effective and promising scientific tools available to mankind. AI and its associated innovations are becoming more popular in industry and culture, and they are starti…
View article: Solubility and solution thermodynamics of raloxifene hydrochloride in various (DMSO + water) compositions
Solubility and solution thermodynamics of raloxifene hydrochloride in various (DMSO + water) compositions Open
The solubility of the poorly soluble drug raloxifene hydrochloride (3) in binary {dimethyl sulfoxide (DMSO) (1) + water (2)} mixtures have been recorded at several temperatures under atmospheric pressure. Four different computational model…