Shailendra Prasad Verma
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View article: Correlation of T Regulatory Cells, Cytotoxic T-lymphocyte-associated Antigen 4, and Transforming Growth Factor-β1 with Treatment Response in Patients with Chronic Myeloid Leukemia Receiving Dasatinib Therapy
Correlation of T Regulatory Cells, Cytotoxic T-lymphocyte-associated Antigen 4, and Transforming Growth Factor-β1 with Treatment Response in Patients with Chronic Myeloid Leukemia Receiving Dasatinib Therapy Open
Background: Tyrosine kinase inhibitors improve chronic myeloid leukemia (CML) outcomes. Dasatinib inhibits breakpoint cluster region-Abelson 1 proto-oncogene tyrosine kinase better than imatinib in CML. T-regulatory cells prevent autoimmun…
View article: A Follow-Up Case of Breast Carcinoma with the Unusual Visitor in Peripheral Blood: Unlock Feathered Edge Secret
A Follow-Up Case of Breast Carcinoma with the Unusual Visitor in Peripheral Blood: Unlock Feathered Edge Secret Open
Background: Breast cancer is the most common cancer in women worldwide and in India. There are very few cases of breast cancer with peripheral blood dissemination having acute leukaemia-like blast cells. Case presentation: Here we present …
View article: Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia
Ring finger protein 138 inhibits transcription factor C/EBPα protein turnover leading to differentiation arrest in acute myeloid leukemia Open
E3 ubiquitin ligase, ring finger protein 138 (RNF138) is involved in several biological processes; however, its role in myeloid differentiation or tumorigenesis remains unclear. RNAseq data from TNMplot showed that RNF138 mRNA levels are h…
View article: Interleukin-6 and Interleukin-8 Levels in Children with Aplastic Anemia and its Correlation with Disease Severity and Response to Immunosuppressive Therapy
Interleukin-6 and Interleukin-8 Levels in Children with Aplastic Anemia and its Correlation with Disease Severity and Response to Immunosuppressive Therapy Open
Background: Aplastic anemia (AA) is an uncommon condition characterized by pancytopenia and hypocellular bone marrow. Interleukin (IL)-6 and IL-8 have been shown to inhibit myelopoiesis and are major mediators of tissue damage. The primary…