Explanipedia

The HEALERS: a patient, community, and stakeholder advisory board focus group series to refine a novel virtual world-based cardiac rehabilitation intervention and clinical trial Open

Helayna Abraham, Grace Patrice Anyetei-Anum, Ashton Krogman, Donald Clark, Melvin Echols , et al. · 2025

Background Cardiac rehabilitation (CR) is a widely underutilized secondary cardiovascular disease prevention strategy, due to a variety of barriers to participation that disproportionately impact women, minoritized racial and ethnic groups…

A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification Open

Sujin Lee, Yugene Guo, Lova Prasadareddy Kajuluri, Kangsan Roh, Kuldeep Singh , et al. · 2025

Vascular calcification represents a convergent pathological feature of diverse cardiovascular diseases, yet the upstream molecular programs orchestrating this process remain poorly defined. Here, we uncover fibronectin type III domain-cont…

Improving Cooking Skills, Lifestyle Behaviors, and Clinical Outcomes for Adults at Risk for Cardiometabolic Disease: Protocol for a Randomized Teaching Kitchen Multisite Trial (TK-MT) Open

Jennifer Massa, Candace Sapp, Kate Janisch, Mopelola A. Adeyemo, Auden C. McClure , et al. · 2025

Background/Objectives: This protocol describes a study to investigate the feasibility and preliminary efficacy of a novel Teaching Kitchen Multisite Trial (TK-MT) for adults with cardiometabolic abnormalities. The TK-MT protocol describes …

Stellate ganglion blockade under ultrasound-guidance and the physiological responses in the rat Open

R. Tran, Shaista Malik, Christopher Reist, Chad K. Oh, Najeebah Abdul-Musawir , et al. · 2025

Stellate ganglion blockade (SGB) is a practical approach to managing many clinical disorders. Ultrasound-guided SGB is currently adopted as a more effective and safer method in humans. Developing this technique in rats would facilitate fur…

Once in a “Blue” Moon: acute myocardial infarction in a 17-year-old male - a diagnostic and therapeutic dilemma Open

Shaista Malik, James H. Stock, Talal Alnabelsi, Preeti Ramachandran · 2025

Pulmonary Hypertension: Pharmacological and Non-Pharmacological Therapies Open

J Tsai, Shaista Malik, Stephanie C. Tjen‐A‐Looi · 2024

Pulmonary hypertension (PH) is a severe and chronic disease characterized by increased pulmonary vascular resistance and remodeling, often precipitating right-sided heart dysfunction and death. Although the condition is progressive and inc…

Feminist Marxist Aesthetics and Women’S Literary Voice: An Analysis of Virginia Woolf’S Essays Open

Shaista Malik, Sammar Zakki, Laiba Anwar · 2024

Art and literature according to Marxist aesthetic theory are part of the social superstructure founded upon the economic infrastructure. Relations of production determine the moral, intellectual and aesthetic values of a particular time ac…

ECG Unveiled: Analysis of Client Re-identification Risks in Real-World ECG Datasets Open

Ziyu Wang, Anil Kanduri, Seyed Amir Hossein Aqajari, Salar Jafarlou, Sanaz Rahimi Moosavi , et al. · 2024

While ECG data is crucial for diagnosing and monitoring heart conditions, it also contains unique biometric information that poses significant privacy risks. Existing ECG re-identification studies rely on exhaustive analysis of numerous de…

Pulmonary Hypertension: Pharmacological and Non-Pharmacological Therapies Open

J Tsai, Shaista Malik, Stephanie C. Tjen‐A‐Looi · 2024

Pulmonary hypertension (PH) is a severe and chronic disease characterized by increased pulmonary vascular resistance and remodeling often precipitating right-sided heart dysfunction and death. Although the condition is progressive and incu…

Does electroacupuncture reducing heart rate rebalance autonomic nervous system? Open

Stephanie C. Tjen‐A‐Looi, Yiwei Gong, Shaista Malik · 2024

Editorial: Therapeutic neuromodulation for aging-related disorders associated with the autonomic nervous system Open

Stephanie Chee Yee Tjen-A-Looi, Liang‐Wu Fu, Shaista Malik, Richard E. Harris, Sae Uchida · 2024

EDITORIAL article Front. Aging Neurosci., 26 March 2024Sec. Neuroinflammation and Neuropathy Volume 16 - 2024 | https://doi.org/10.3389/fnagi.2024.1399972

Efficacy and Adherence Rates of a Novel Community‐Informed Virtual World‐Based Cardiac Rehabilitation Program: Protocol for the <i>Destination Cardiac Rehab</i> Randomized Controlled Trial Open

LaPrincess C. Brewer, Helayna Abraham, Donald Clark, Melvin Echols, Michael E. Hall , et al. · 2023

Background Innovative restructuring of cardiac rehabilitation (CR) delivery remains critical to reduce barriers and improve access to diverse populations. Destination Cardiac Rehab is a novel virtual world technology‐based CR program deliv…

Adenosine A2A receptors in the rostral ventrolateral medulla participate in blood pressure decrease with electroacupuncture in hypertensive rats Open

Zhi‐Ling Guo, Stephanie C. Tjen‐A‐Looi, Anh T. Nguyen, Liang‐Wu Fu, Houfen Su , et al. · 2023

Acupuncture is increasingly used to manage high blood pressure (BP) as a complementary therapy. However, the mechanisms underlying its hypotensive effects remain unclear. Our previous studies have shown that electroacupuncture (EA) at the …

Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification Open

Maryam Kavousi, Maxime M. Bos, Hanna J. Barnes, Christian L. Lino Cardenas, Doris Wong , et al. · 2023

Sympathoinhibitory electroacupuncture (EA) interacts positively with anti-inflammatory EA alleviating blood pressure in hypertensive rats Open

Liang‐Wu Fu, Yiwei Gong, Anh T. Nguyen, Zhi‐Ling Guo, Stephanie C. Tjen‐A‐Looi , et al. · 2023

Elevated sympathetic activity and chronic inflammation are known contributory factors observed in hypertension. We have observed that sympathoinhibitory electroacupuncture (SI-EA) at acupoints ST36-37 alleviates sympathetic activity and hy…

Lipid-Lowering Nutraceuticals for an Integrative Approach to Dyslipidemia Open

Brian Cheung, Geeta Sikand, Elizabeth H. Dineen, Shaista Malik, Ailin Barseghian El-Farra · 2023

Dyslipidemia is a treatable risk factor for atherosclerotic cardiovascular disease that can be addressed through lifestyle changes and/or lipid-lowering therapies. Adherence to statins can be a clinical challenge in some patients due to st…

Electroacupuncture for the management of symptom clusters in cancer patients and survivors (EAST) Open

Lifang Xie, Ding Quan Ng, Matthew Heshmatipour, Munjal M. Acharya, Paul Coluzzi , et al. · 2023

Background Neuropsychiatric symptoms, comprising cognitive impairment, fatigue, insomnia, depression, and anxiety, are prevalent and may co-occur during and after chemotherapy treatment for cancer. Electroacupuncture (EA), which involves m…

Coronary calcium density in relation to coronary heart disease and cardiovascular disease in adults with diabetes or metabolic syndrome: the Multi-ethnic Study of Atherosclerosis (MESA) Open

Yanglu Zhao, Shaista Malik, Michael H. Criqui, Matthew Allison, Matthew J. Budoff , et al. · 2022

Dietary potassium intake, kidney function, and survival in a nationally representative cohort Open

Yoko Narasaki, Amy S. You, Shaista Malik, Linda W. Moore, Rachelle Bross , et al. · 2022

Association of polygenic risk scores with incident atherosclerotic cardiovascular disease events among individuals with coronary artery calcium score of zero: The multi-ethnic study of atherosclerosis Open

Mahmoud Al Rifai, Jie Yao, Xiuqing Guo, Wendy S. Post, Shaista Malik , et al. · 2022

Sympathoinhibitory Electroacupuncture (EA) Interacts Positively with Anti-Inflammatory EA Alleviating Blood Pressure in Hypertensive Rats Open

Liang‐Wu Fu, Yiwei Gong, Anh T. Nguyen, Zhi‐Ling Guo, Stephanie C. Tjen‐A‐Looi , et al. · 2022

Elevated sympathetic activity and chronic inflammation are known contributory factors observed in hypertension.We have observed that sympathoinhibitory electroacupuncture (SI-EA) at acupoints ST36-37 alleviates sympathetic activity and hyp…

Neurogenic Hypotension and Bradycardia Modulated by Electroacupuncture in Hypothalamic Paraventricular Nucleus Open

Stephanie C. Tjen‐A‐Looi, Liang‐Wu Fu, Zhi‐Ling Guo, Yiwei Gong, Anh T. Nguyen , et al. · 2022

Electroacupuncture (EA) stimulates somatic median afferents underlying P5-6 acupoints and modulates parasympathoexcitatory reflex responses through central processing in the brainstem. Although decreases in blood pressure and heart rate by…

Cardiodiagnostic sex-specific differences of the female athlete in sports cardiology Open

Vishal Patel, Irmina Gradus‐Pizlo, Shaista Malik, Ailin Barseghian El-Farra, Elizabeth H. Dineen · 2022

The cardiovascular care of highly active individuals and competitive athletes has developed into an important focus within the field of sports medicine. An evolving understanding of exercise-induced cardiovascular remodeling in athletes ha…

VISUAL SOVEREIGNTY IN SMOKE SIGNALS: A CRITICAL VISUAL ANALYSIS Open

Shaista Malik, Ayaz Muhammad Shah, Farhat Nawaz · 2022

The current research paper aims to see a film Smoke Signals by American Indian writer Sherman Alexie and director Chris Eyre as an attempt to define visual sovereignty. By applying Critical Visual Theory, the paper seeks to provide not jus…

Politico-cultural appropriation of Native American in American Indian poetry and drama: Unflinchingly documents the halfway existence Open

Shaista Malik, Samar Zakki, Dur-e-Afsha, Wajid Riaz · 2021

During the Twentieth century Native American literature evolved from anonymity into prominence by assuming a commitment to reflect the particular challenges that faced Native American people during last two centuries. Native American Liter…

Identification and Predictors for Cardiovascular Disease Risk Equivalents Among Adults With Diabetes Open

Yanglu Zhao, Shaista Malik, Matthew J. Budoff, Adolfo Correa, Kellan E. Ashley , et al. · 2021

OBJECTIVE We examined diabetes as a cardiovascular disease (CVD) risk equivalent based on diabetes severity and other CVD risk factors. RESEARCH DESIGN AND METHODS We pooled four U.S. cohorts (Atherosclerosis Risk in Communities [ARIC], Ja…

Identification and Predictors for Cardiovascular Disease Risk Equivalents among Adults With Diabetes Mellitus Open

Yanglu Zhao, Shaista Malik, Matthew J. Budoff, Adolfo Correa, Kellan E. Ashley , et al. · 2021

Objective: We examined diabetes mellitus (DM) as a cardiovascular disease (CVD) risk equivalent based on diabetes severity and other CVD risk factors. Research Design and Methods: We pooled 4 US cohorts (ARIC, JHS, MESA, FHS-Offspring) and…

Identification and Predictors for Cardiovascular Disease Risk Equivalents among Adults With Diabetes Mellitus Open

Yanglu Zhao, Shaista Malik, Matthew J. Budoff, Adolfo Correa, Kellan E. Ashley , et al. · 2021

Objective: We examined diabetes mellitus (DM) as a cardiovascular disease (CVD) risk equivalent based on diabetes severity and other CVD risk factors. Research Design and Methods: We pooled 4 US cohorts (ARIC, JHS, MESA, FHS-Offspring) and…

SURVIVAL UNDER DURESS: ANARCHIST CRITIQUE OF THINNER THAN SKIN Open

Shaista Malik, Abdul Shakoor, Ayaz Muhammad Shah, Wajid Riaz · 2021

Purpose of the study: This study used an Anarchist framework to prove that Thinner than Skin by Uzma Aslam Khan explores the causes of the peripheral communities' shared precariousness and their fight to sustain and conserve life in a worl…

Impact of Social Media on Academic Performance Open

Manahil Jamil, Qurat ul Ain, Salma Batool, Sidra Saadat, Shaista Malik , et al. · 2020

Social media is a mode of communication, influencing nearly every field of life. Researchers have found that the use of social media can be addictive, which may cause significant impairment in various aspects of an individual’s life. This …

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