Shakoor Pooseh
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View article: Connection Failure: Differences in White Matter Microstructure Are Associated with 5-HTTLPR but Not with Risk Seeking for Losses
Connection Failure: Differences in White Matter Microstructure Are Associated with 5-HTTLPR but Not with Risk Seeking for Losses Open
S/S carriers of 5-HTTLPR have been found to be more risk seeking for losses compared to L/L carriers. This finding may be the result of reduced top-down control from the frontal cortex due to altered signal pathways involving the amygdala …
View article: Comparative investigation of appraisal style measures in their predictive potential for stress resilience and implications for predictive modeling of resilience
Comparative investigation of appraisal style measures in their predictive potential for stress resilience and implications for predictive modeling of resilience Open
Appraisal refers to the evaluation of stimuli or situations with respect to an individual’s goals and needs. Stimuli or situations that are appraised as a threat to one’ goals and needs (‘stressors’) induce stress responses (‘stress’). Str…
View article: Intraindividual time-varying dynamic network of affects: linear autoregressive mixed-effects models for ecological momentary assessment
Intraindividual time-varying dynamic network of affects: linear autoregressive mixed-effects models for ecological momentary assessment Open
An interesting recent development in emotion research and clinical psychology is the discovery that affective states can be modeled as a network of temporally interacting moods or emotions. Additionally, external factors like stressors or …
View article: Arbitration between model-free and model-based control is not affected by transient changes in tonic serotonin levels
Arbitration between model-free and model-based control is not affected by transient changes in tonic serotonin levels Open
Background: Serotonin has been suggested to modulate decision-making by influencing the arbitration between model-based and model-free control. Disruptions in these control mechanisms are involved in mental disorders such as drug dependenc…
View article: Psychological Resilience Factors and Their Association With Weekly Stressor Reactivity During the COVID-19 Outbreak in Europe: Prospective Longitudinal Study
Psychological Resilience Factors and Their Association With Weekly Stressor Reactivity During the COVID-19 Outbreak in Europe: Prospective Longitudinal Study Open
Background Cross-sectional relationships between psychosocial resilience factors (RFs) and resilience, operationalized as the outcome of low mental health reactivity to stressor exposure (low “stressor reactivity” [SR]), were reported duri…
View article: Investigating two mobile just-in-time adaptive interventions to foster psychological resilience: research protocol of the DynaM-INT study
Investigating two mobile just-in-time adaptive interventions to foster psychological resilience: research protocol of the DynaM-INT study Open
View article: Psychological Resilience Factors and Their Association With Weekly Stressor Reactivity During the COVID-19 Outbreak in Europe: Prospective Longitudinal Study (Preprint)
Psychological Resilience Factors and Their Association With Weekly Stressor Reactivity During the COVID-19 Outbreak in Europe: Prospective Longitudinal Study (Preprint) Open
BACKGROUND Cross-sectional relationships between psychosocial resilience factors (RFs) and resilience, operationalized as the outcome of low mental health reactivity to stressor exposure (low “stressor reactivity” [SR]), were reported dur…
View article: Dynamic Modelling of Mental Resilience in Young Adults: Protocol for a Longitudinal Observational Study (DynaM-OBS)
Dynamic Modelling of Mental Resilience in Young Adults: Protocol for a Longitudinal Observational Study (DynaM-OBS) Open
Background Stress-related mental disorders are highly prevalent and pose a substantial burden on individuals and society. Improving strategies for the prevention and treatment of mental disorders requires a better understanding of their ri…
View article: Psychological resilience factors and their association with weekly stressor reactivity during the COVID-19 outbreak in Europe
Psychological resilience factors and their association with weekly stressor reactivity during the COVID-19 outbreak in Europe Open
Recently, cross-sectional relationships between psycho-social resilience factors (RFs) and resilience, operationalized as an outcome of low reactivity of mental health to stressor exposure (low ‘stressor reactivity’) during the first wave …
View article: Dynamic Modelling of Mental Resilience in Young Adults: Protocol for a Longitudinal Observational Study (DynaM-OBS) (Preprint)
Dynamic Modelling of Mental Resilience in Young Adults: Protocol for a Longitudinal Observational Study (DynaM-OBS) (Preprint) Open
BACKGROUND Stress-related mental disorders are highly prevalent and pose a substantial burden on individuals and society. Improving strategies for the prevention and treatment of mental disorders requires a better understanding of their r…
View article: Psychological resilience factors and their association with weekly stressor reactivity during the COVID-19 outbreak in Europe
Psychological resilience factors and their association with weekly stressor reactivity during the COVID-19 outbreak in Europe Open
Recently, cross-sectional relationships between psycho-social resilience factors (RFs) and resilience, operationalized as an outcome of low reactivity of mental health to stressor exposure (low ‘stressor reactivity’) during the first wave …
View article: Individualizing deep dynamic models for psychological resilience data
Individualizing deep dynamic models for psychological resilience data Open
View article: No Differences in Value-Based Decision-Making Due to Use of Oral Contraceptives
No Differences in Value-Based Decision-Making Due to Use of Oral Contraceptives Open
Fluctuating ovarian hormones have been shown to affect decision-making processes in women. While emerging evidence suggests effects of endogenous ovarian hormones such as estradiol and progesterone on value-based decision-making in women, …
View article: Study protocol description: Dynamic Modelling of Resilience - Observational Study (DynaM-OBS)
Study protocol description: Dynamic Modelling of Resilience - Observational Study (DynaM-OBS) Open
Stress-related mental disorders are highly prevalent and pose a significant burden on individuals and society. Improving strategies of their treatment and prevention requires knowledge about risk and resilience. This multi-center study aim…
View article: Weekly dynamics of stressor resilience and protective factors during the COVID-19 outbreak in Europe
Weekly dynamics of stressor resilience and protective factors during the COVID-19 outbreak in Europe Open
View article: Connection Failure: Differences in White Matter Microstructure are associated with<i>5-HTTLPR</i>but not with Risk-Seeking for Losses
Connection Failure: Differences in White Matter Microstructure are associated with<i>5-HTTLPR</i>but not with Risk-Seeking for Losses Open
In a previous study (Neukam, Kroemer et al. 2018), we found for the 5-HTTLPR genotype higher risk-seeking for losses in S/S vs. L/L carrier, which could not be explained by acutely changed central serotonin levels. This finding alternative…
View article: Probabilistic Reversal Learning Deficits in Patients With Methamphetamine Use Disorder—A Longitudinal Pilot Study
Probabilistic Reversal Learning Deficits in Patients With Methamphetamine Use Disorder—A Longitudinal Pilot Study Open
Methamphetamine use disorder (MUD) is increasing worldwide and commonly associated with learning deficits. Little is known the about underlying trajectories, i.e., how the affected higher-order cognitive functions develop over time and wit…
View article: Temporal discounting and smoking cessation: choice consistency predicts nicotine abstinence in treatment-seeking smokers
Temporal discounting and smoking cessation: choice consistency predicts nicotine abstinence in treatment-seeking smokers Open
View article: Individualizing deep dynamic models for psychological resilience data
Individualizing deep dynamic models for psychological resilience data Open
Deep learning approaches can uncover complex patterns in data. In particular, variational autoencoders (VAEs) achieve this by a non-linear mapping of data into a low-dimensional latent space. Motivated by an application to psychological re…
View article: Neurocognitive Dysfunctions and Their Therapeutic Modulation in Patients With Methamphetamine Dependence: A Pilot Study
Neurocognitive Dysfunctions and Their Therapeutic Modulation in Patients With Methamphetamine Dependence: A Pilot Study Open
AIM: Methamphetamine (MA) abuse and dependence are increasing worldwide and are commonly associated with cognitive deficits. Some studies indicate that such impairments can improve if users become abstinent, but overall results remain inco…
View article: Metabolic state and value-based decision-making in acute and recovered female patients with anorexia nervosa
Metabolic state and value-based decision-making in acute and recovered female patients with anorexia nervosa Open
Background: Patients with anorexia nervosa forgo eating despite emaciation and severe health consequences. Such dysfunctional decision-making might be explained by an excessive level of self-control, alterations in homeostatic and hedonic …
View article: Impulsive decision-making predicts the course of substance-related and addictive disorders
Impulsive decision-making predicts the course of substance-related and addictive disorders Open
View article: Individual differences in dopamine function underlying the balance between model-based and model-free control
Individual differences in dopamine function underlying the balance between model-based and model-free control Open
Reinforcement learning involves a balance between model-free (MF) and model-based (MB) systems. Recent studies suggest that individuals with either pharmacologically enhanced levels of dopamine (DA) or higher baseline levels of DA exhibit …
View article: Presynaptic dopamine function measured with [18F]fluorodopa and L-DOPA effects on impulsive choice
Presynaptic dopamine function measured with [18F]fluorodopa and L-DOPA effects on impulsive choice Open
View article: Baseline impulsivity may moderate L-DOPA effects on value-based decision-making
Baseline impulsivity may moderate L-DOPA effects on value-based decision-making Open
Research has indicated a major role of dopamine in decision-making processes, but the underlying mechanisms remain largely unknown due to inconsistency in effects of dopaminergic drugs. To clarify the impact of dopamine on impulsive choice…
View article: Strong seduction: impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence
Strong seduction: impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence Open
View article: Value-based decision-making battery: A Bayesian adaptive approach to assess impulsive and risky behavior
Value-based decision-making battery: A Bayesian adaptive approach to assess impulsive and risky behavior Open
View article: L-DOPA Reduces Model-Free Control of Behavior by Attenuating the Transfer of Value to Action
L-DOPA Reduces Model-Free Control of Behavior by Attenuating the Transfer of Value to Action Open
Dopamine is a key neurotransmitter in reinforcement learning and action control. Recent findings suggest that these components are inherently entangled. Here, we tested if increases in dopamine tone by administration of L-DOPA upregulate d…