Explanipedia

Utility of Lung Ultrasonography for Early Diagnosis and Monitoring of Ventilator-associated Pneumonia in Mechanically Ventilated Patients: A Prospective Observational Study Open

Shakti Bedanta Mishra, Satyajit Choudhury, Pritam Chhotray, Shantanu K Patra, Sagarika Panda , et al. · 2025

Roy C, Choudhury S, Chhotray P, Patra ESK, Panda S, Mishra SB. Utility of Lung Ultrasonography for Early Diagnosis and Monitoring of Ventilator-associated Pneumonia in Mechanically Ventilated Patients: A Prospective Observational Study. In…

Candida auris infections in ICU patients: risk factors, outcomes, and antifungal resistance patterns Open

Satyajit Choudhury, Kalpana Majhi, P. K. Jena, Sritam Mohanty, Yallawar Nipun Narayan , et al. · 2025

BACKGROUND: Candida auris has emerged as a major nosocomial pathogen in intensive care units worldwide due to its multidrug resistance, environmental persistence, and high transmission potential. While several outbreak reports exist, there…

Thermodynamic modeling adsorption behavior of a well-known gelation crosslinker on sandstone rocks Open

Yue Yang, Ayat Hussein Adhab, Dharmesh Sur, Soumya V. Menon, Abhayveer Singh , et al. · 2025

Regenerative potential of PRP-based scaffolds in chronic wound healing: Mechanisms, advances, and therapeutic insights Open

Farag M. A. Altalbawy, Bilal Abdul Majeed Mukhlif, Ahemad Hussen, Jaafaru Sani Mohammed, Renuka Jyothi S , et al. · 2025

Septic Hepatopathy: Incidence, Characteristics, and Outcomes among Critically Ill Patients In A Two-year Retrospective Analysis Open

Shakti Bedanta Mishra, Samir Samal, FNU Pragati · 2025

INTRODUCTION: Septic hepatopathy, defined as liver dysfunction occurring in the setting of systemic infection, is a recognised complication in critically ill patients with sepsis.(2,4) Its incidence and severity have been associated with w…

Impact of Fluid Balance on Extubation Outcomes in Critically Ill Patients: A Retrospective Analysis Open

Shakti Bedanta Mishra, Abhilash Dash, Satyajit Choudhury · 2025

INTRODUCTION: Extubation readiness in the ICU involves assessing multiple physiological and clinical factors. Recent research has shown the role of fluid balance in successful weaning from mechanical ventilation, with a positive fluid bala…

Vasopressor Dependency as A Predictor of Mortality in Septic Shock Open

Sagarika Panda, Shakti Bedanta Mishra, Samir Samal, Satyajit Choudhury · 2025

INTRODUCTION: Septic shock ensues when sepsis-induced hypotension remains refractory to fluid resuscitation. Mean arterial pressure is the key determinant of increased tissue blood flow and perfusion. Guideline recommends initial target me…

Clinical Implications and Outcome Analysis of Dysnatremia in Critically Ill Patients in ICU in a Tertiary Care Hospital in Eastern India Open

Sagarika Panda, Shakti Bedanta Mishra, S Anushapreethi · 2025

INTRODUCTION: Serum sodium measurements are obtained routinely in intensive care unit (ICU) patient. Clinical manifestations of dysnatremia are primarily neurological and rapid changes can cause severe, permanent, even lethal brain injury(…

Microbial Trends and Antibiotic Susceptibility in ICU-Admitted Patients: A Hospital-Based Study Examining Prevalence Across Multiple Critical Therapies Open

Kalaivani Ramakrishnan, Shakti Bedanta Mishra, Jasdeep Monga, Paramjit Baxi, Kothakonda Sairam , et al. · 2025

Healthcare practitioners can adjust treatment plans, choose efficient antimicrobial agents, enhance patient outcomes, reduce antibiotic-resistant strains and ultimately improve patient outcomes by keeping an observation on microbial trends…

Hemodynamic effects of adjunct arginine vasopressin to norepinephrine in septic shock: insights from a prospective multicenter registry study Open

Max Melchers, Vivienne de Smet, Chrissie Rooijakkers, Jonathan Huising, W Vermeulen , et al. · 2025

Complication management in percutaneous dilatational tracheostomy: a case of tracheal needle sheath retrieval Open

Sritam Mohanty, Biswajit Nayak, Samir Samal, Sagarika Panda, Shakti Bedanta Mishra , et al. · 2025

Tubercular Vasculitis: A Rare Occurrence Open

Abhijit Acharya, Anusha Preethi, Shakti Bedanta Mishra, Sagarika Panda, Sumirini Puppala · 2025

Tuberculosis (TB) is a community-acquired disease, caused by Mycobacterium tuberculosis , largely prevalent in Southeast Asian countries. Pulmonary and extrapulmonary TB in India is rampant, and a national program has been implemented for …

Assessing Ethical Challenges in End-of-Life Decision-Making Through a Case Study Approach Open

Keshav Keshav, Manashree Mane, Swarna Swetha Kolaventi, Shakti Bedanta Mishra, Mekala Ishwarya , et al. · 2024

For patients, families, doctors, and legislators, end-of- life decisions create major ethical conundrums. The moral conundrums in clinical practice arise from the growing complexity of medical procedures, legal differences among countries,…

Lung Ultrasound Score as a Predictor of Clinical Severity and Prognosis in Patients of Ventilator-associated Pneumonia Open

Sagarika Panda, Ankit Agarwal, Shakti Bedanta Mishra, Gaurav Jain, Praveen Talawar · 2024

Panda S, Agarwal A, Mishra SB, Jain G, Talawar P. Lung Ultrasound Score as a Predictor of Clinical Severity and Prognosis in Patients of Ventilator-associated Pneumonia. Indian J Crit Care Med 2024;28(11):1009-1014.

Nebulized aminoglycosides for ventilator-associated pneumonia: Methodological considerations and lessons from experimental studies Open

Jean‐Jacques Rouby, Jing Xia, Jayesh Dhanani, Gianluigi Li Bassi, Antoine Monsel , et al. · 2024

Serial Trend of Neutrophil CD64, C-reactive Protein, and Procalcitonin as a Prognostic Marker in Critically Ill Patients with Sepsis/Septic Shock: A Prospective Observational Study from a Tertiary Care ICU Open

Rupali Patnaik, Afzal Azim, Kritika Singh, Vikas Agarwal, Prabhakar Mishra , et al. · 2024

Patnaik R, Azim A, Singh K, Agarwal V, Mishra P, Poddar B, et al. Serial Trend of Neutrophil CD64, C-reactive Protein, and Procalcitonin as a Prognostic Marker in Critically Ill Patients with Sepsis/Septic Shock: A Prospective Obser…

Reversible Causes of Cardiac Arrest by Sonological Transthoracic AssessmenT (ReSTAT) in Predicting Reversible Cardiac Arrest Scenarios: A Retrospective Observational Study Open

Tatikonda Chandra Mouli, Satyajit Choudhury, Samir Samal, Shakti Bedanta Mishra, Shweta Rao , et al. · 2024

Background: Cardio-pulmonary resuscitation has taken a front seat in the recent past. Guidelines of the Indian Resuscitation Council (IRC) focused on reversible causes of cardiac arrest. However, the delay in achieving the return of sponta…

A Prospective Observational Study on the Correlation Between Vexus Score and Cumulative Fluid Balance in Septic Shock Patients During ICU Stay Open

Sagarika Panda, Shakti Bedanta Mishra, Samir Samal, Swathi Kondala · 2024

INTRODUCTION: Sepsis is a dysregulated inflammatory response to an infection that may result in septic shock. In the initial phase of septic shock, large quantities of fluid are to be administered which may result in venous congestion. Ven…

Assessment of quality of life in follow-up patients with COVID-19 pneumonia: A prospective, observational study from a tertiary care center Open

Tatikonda Chandra Mouli, Rupali Patnaik, Samir Samal, Shakti Bedanta Mishra · 2024

BACKGROUND: This study intended to assess the quality of life (QOL) with telephonic interview using the Short Form 12 (SF-12) Scale in follow-up patients admitted to the intensive care unit (ICU) with COVID-19 pneumonia. METHODS: This pros…

Designing Effective Occupational Safety Training Modules Tailored for Healthcare Practitioners Open

Mahesh Sharma, Shakti Bedanta Mishra, H Malathi, Swapna Ajay Shedge, Mohammad Mohnish · 2023

Safety on the job is very important in healthcare situations because workers are at a higher risk of getting hurt or sick. Establishing efficient job safety training courses tailored to healthcare professionals helps to provide a safe work…

Thermo-Reversible Hydrogel Systems for Customized Drug Release in Chronic Periodontal Disease Treatment Open

K. V. Jamuna, Abhishek Kumar Mishra, Shakti Bedanta Mishra · 2023

Effective drug delivery systems are crucial for treating chronic periodontal disease, where sustained and localized drug release is essential. The aim is to investigate the potential of thermo-reversible hydrogel systems for controlled dru…

A systematic review and meta-analysis of randomized controlled trials with trial sequence analysis of remdesivir for COVID-19 treatment Open

Rupali Patnaik, Tatikonda Chandramouli, Shakti Bedanta Mishra · 2023

Remdesivir is one of the proposed therapies for the corona virus disease 2019 (COVID-19). To assess the effect of remdesivir on mortality, need for invasive mechanical ventilation (IMV) and extracorporeal membrane oxygenation (ECMO), time …

Burkholderia pseudomallei Brain Abscess: Atypical Infection at the Atypical Site: A Case Report Open

Shakti Bedanta Mishra, Satyajit Choudhury, Sagarika Panda, S Anushapreethi, Pragnya Paramita Jena · 2023

shifted to the intensive care unit (ICU) with an endotracheal tube in situ and subsequently put on the mechanical ventilator.However, he had multiple episodes of GTCS subsequently, for which the dose of the first antiepileptic was escalate…

An international prospective study of INICC analyzing the incidence and risk factors for catheter-associated urinary tract infections in 235 ICUs across 8 Asian Countries Open

Víctor Rosenthal, Ruijie Yin, Lilian M. Abbo, Brandon Lee, Camilla Rodrigues , et al. · 2023

It is suggested to focus on reducing the length of stay and the Urinary catheter device utilization ratio, avoiding suprapubic catheters, and implementing evidence-based CAUTI prevention recommendations.

Tocilizumab in severe COVID-19 pneumonia: A retrospective case-control study from eastern India Open

Tatikonda Chandra Mouli, Rohit Kumar Patnaik, Shakti Bedanta Mishra · 2023

Miller Fisher Variant of Guillain-Barre Syndrome Secondary to Pulmonary Tuberculosis: A Case Report with Review of Literature Open

Chandra Mouli Tatikonda, Kaushik Rao Juvvadi, Sagarika Panda, Shakti Bedanta Mishra, Abhilash Dash · 2023

Guillain-Barre syndrome (GBS) is one of the common causes for acute flaccid paralysis in adults and mostly preceded by infection. Miller Fisher syndrome (MFS) is a rare variant of GBS with incidence of 1 to 2 in 1,000,000. This syndrome ha…

Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study Open

Romain Sonneville, Étienne de Montmollin, Damien Contou, Ricard Ferrer, Mohan Gurjar , et al. · 2023

Post COVID Thrombotic Sequelae: Once Bitten, Twice Shy! Open

Cherian Roy, Rohit Kumar Patnaik, Samir Samal, Shakti Bedanta Mishra, Nupur Karan · 2023

Introduction Long Covid has been recognized as a distinct entity with thrombotic sequelae [1]. Persistent systemic vascular inflammation caused by thrombosis drives the complications associated with long COVID. The risks of arterial and ve…

Airway Pressure Release Ventilation in COVID-19: There’s More to This Than Meets the Eye Open

Rohit Kumar Patnaik, Shakti Bedanta Mishra, Samir Samal · 2022

All authors: Department of Critical Care Medicine, Institute of Medical Sciences and SUM Hospital, Bhubaneswar, India Author Contribution: Dr. Patnaik helped with concept, design, literature search, data acquisition, article preparation, e…

Risk factors and clinical outcomes of carbapenem-resistant Klebsiella pneumonia infection in intensive care unit Open

Sagarika Panda, Abhilash Dash, Pritam Chhotray, Biswajit Nayak, Tatikonda Chandra Mouli , et al. · 2022

Background: Carbapenem-resistant Enterobacteriaceae, especially Klebsiella pneumonia , have become a severe global problem with a significant threat to public health, but few studies have investigated the risk factors and epidemiology of c…

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