Shamanth A. Shankarnarayan
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View article: Peering Inside the Black Box: Explainable AI to Interpret Advanced Computer Vision Fungal Pathogen Prediction
Peering Inside the Black Box: Explainable AI to Interpret Advanced Computer Vision Fungal Pathogen Prediction Open
Antimicrobial resistance is a growing concern, with pathogenic fungi making a substantial contribution to untreatable life-threatening infections across the globe. Artificial intelligence is increasingly used in microbiology and antimicrob…
View article: Machine learning to identify clinically relevant<i>Candida</i>yeast species
Machine learning to identify clinically relevant<i>Candida</i>yeast species Open
Background Fungal infections, especially due to Candida species, are on the rise. Multi-drug resistant organism such as Candida auris are difficult and time consuming to identify accurately. Machine learning is increasingly being used in h…
View article: Comprehensive Taxonomical Analysis of Trichophyton Mentagrophytes/Interdigitale Complex of Human and Animal Origin from India
Comprehensive Taxonomical Analysis of Trichophyton Mentagrophytes/Interdigitale Complex of Human and Animal Origin from India Open
Taxonomic delineation of etiologic agents responsible for recalcitrant dermatophytosis causing an epidemic in India is still debated. The organism responsible for this epidemic is designated as T. indotineae, a clonal offshoot of T. mentag…
View article: Identification and Elimination of Antifungal Tolerance in Candida auris
Identification and Elimination of Antifungal Tolerance in Candida auris Open
Antimicrobial resistance is a global health crisis to which pathogenic fungi make a substantial contribution. The human fungal pathogen C. auris is of particular concern due to its rapid spread across the world and its evolution of multidr…
View article: Identification and Elimination of Antifungal Tolerance in<i>Candida auris</i>
Identification and Elimination of Antifungal Tolerance in<i>Candida auris</i> Open
Antimicrobial resistance is a global health crisis to which pathogenic fungi make a substantial contribution. The human fungal pathogen C. auris is of particular concern due to its rapid spread across the world and its evolution of multidr…
View article: P096 Comprehensive analysis of <i>Trichophyton mentagrophytes</i>/interdigitale complex from human and animal origin
P096 Comprehensive analysis of <i>Trichophyton mentagrophytes</i>/interdigitale complex from human and animal origin Open
Poster session 1, September 21, 2022, 12:30 PM - 1:30 PM Objectives Taxonomic delineation of etiologic agents responsible for recalcitrant dermatophytosis causing epidemic in India is still debated. The organism responsible for this epidem…
View article: Machine Learning for Antimicrobial Resistance Research and Drug Development
Machine Learning for Antimicrobial Resistance Research and Drug Development Open
Machine learning is a subfield of artificial intelligence which combines sophisticated algorithms and data to develop predictive models with minimal human interference. This chapter focuses on research that trains machine learning models t…
View article: Fatal cerebral phaeohyphomycosis caused by Cladophialophora bantiana mimicking tuberculous brain abscess
Fatal cerebral phaeohyphomycosis caused by Cladophialophora bantiana mimicking tuberculous brain abscess Open
Fungal etiology should be considered in the differential diagnosis of intracranial space occupying lesions, regardless of the host immune status. An early diagnosis, together with aggressive medical and neurosurgical interventions are impe…
View article: Cunninghamella arunalokei a New Species of Cunninghamella from India Causing Disease in an Immunocompetent Individual
Cunninghamella arunalokei a New Species of Cunninghamella from India Causing Disease in an Immunocompetent Individual Open
Mucormycosis due to Cunninghamella spp. is a rare disease, especially in immunocompetent individuals. Here, we describe the isolation and characterization of a new species of Cunninghamella, causing chronic rhino-orbital-cerebral disease, …
View article: A Selective Medium for Isolation and Detection of Candida auris, an Emerging Pathogen
A Selective Medium for Isolation and Detection of Candida auris, an Emerging Pathogen Open
Identification of Candida auris is challenging and requires molecular or protein profiling-based approaches, availability of which is limited in many routine diagnostic laboratories, necessitating the development of a cost-effective, rapid…
View article: Caspofungin resistance in<i>Candia auris</i>due to mutations in<i>Fks</i>1 with adjunctive role of chitin and key cell wall stress response pathway genes
Caspofungin resistance in<i>Candia auris</i>due to mutations in<i>Fks</i>1 with adjunctive role of chitin and key cell wall stress response pathway genes Open
The emergence of echinocandin resistance in C. auris has become a major concern. Point mutations in Fks1 subunit of β-D-glucan synthase is the primary mechanism in echinocandin resistance. However, resistant isolates with wild type Fks 1 a…
View article: Rapid detection of terbinafine resistance in Trichophyton species by Amplified refractory mutation system-polymerase chain reaction
Rapid detection of terbinafine resistance in Trichophyton species by Amplified refractory mutation system-polymerase chain reaction Open
Dermatophytosis has gained interest in India due to rise in terbinafine resistance and difficulty in management of recalcitrant disease. The terbinafine resistance in dermatophytes is attributed to single nucleotide polymorphisms (SNPs) in…
View article: Molecular Typing and Antifungal Susceptibility of <i>Candida viswanathii,</i> India
Molecular Typing and Antifungal Susceptibility of <i>Candida viswanathii,</i> India Open
We report invasive candidiasis caused by Candida viswanathii over 2 time periods during 2013-2015 in a tertiary care hospital in Chandigarh, India. Molecular typing revealed multiple clusters of the isolates. We detected high MICs for fluc…
View article: Mutation in the Squalene Epoxidase Gene of Trichophyton interdigitale and Trichophyton rubrum Associated with Allylamine Resistance
Mutation in the Squalene Epoxidase Gene of Trichophyton interdigitale and Trichophyton rubrum Associated with Allylamine Resistance Open
Dermatophytosis, the commonest superficial fungal infection, has gained recent attention due to its change of epidemiology and treatment failures. Despite the availability of several agents effective against dermatophytes, the incidences o…