Xiang‐Shan Wang
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View article: A systematic review and meta-analysis of Anterior Cervical Decompression and Fusion: Comparing the ROI-CTM Self-Locking System with Traditional Cage-Plate Internal Fixation in the Treatment of Degenerative Cervical Spondylosis
A systematic review and meta-analysis of Anterior Cervical Decompression and Fusion: Comparing the ROI-CTM Self-Locking System with Traditional Cage-Plate Internal Fixation in the Treatment of Degenerative Cervical Spondylosis Open
Objective: Anterior Cervical Decompression and Fusion (ACDF) is a well-established surgical intervention for degenerative cervical spondylosis. While the use of plates is known to improve fusion rates and stability, it may also be associat…
View article: Access to Carbonyl Azides via Iodine(III)-Mediated Cross-Coupling
Access to Carbonyl Azides via Iodine(III)-Mediated Cross-Coupling Open
Herein, we present a prominent metal-free C-N cross-coupling platform that enables access to carbamoyl- and ketoazides from isocyanides or silyl enol ethers and trimethylsilyl azide (TMSN3) with an aid of iodine(III) promoter. This offers …
View article: Silver-Catalyzed Radical Umpolung Cross-Coupling of Silyl Enol Ethers with Activated Methylene Compounds: Access to Diverse Tricarbonyl Derivatives
Silver-Catalyzed Radical Umpolung Cross-Coupling of Silyl Enol Ethers with Activated Methylene Compounds: Access to Diverse Tricarbonyl Derivatives Open
A silver-catalyzed protocol for the intermolecular radical umpolung cross-coupling protocol of silyl enol ethers with activated methylene compounds is disclosed. The protocol exhibits excellent functional group tolerance, enabling the expe…
View article: General Approach to Amides through Decarboxylative Radical Cross-Coupling of Carboxylic Acids and Isocyanides
General Approach to Amides through Decarboxylative Radical Cross-Coupling of Carboxylic Acids and Isocyanides Open
Herein, we report a silver-catalyzed protocol for decarboxylative cross-coupling between carboxylic acids and isocyanides, leading to linear amide products through a free-radical mechanism. The disclosed approach provides a general entry t…
View article: CCDC 2210931: Experimental Crystal Structure Determination
CCDC 2210931: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2210960: Experimental Crystal Structure Determination
CCDC 2210960: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Construction of Phenanthridinone Skeletons through Palladium-Catalyzed Annulation
Construction of Phenanthridinone Skeletons through Palladium-Catalyzed Annulation Open
Herein, a straightforward synthetic approach for the construction of phenanthridin-6(5H)-one skeletons is disclosed. The developed protocol relies on palladium catalysis, providing controlled access to a range of functionalized phenanthrid…
View article: Copper-Catalyzed Synthesis of <i>β</i>-Keto Sulfones from Enol Silyl Ether and Sodium Arylsulfinates
Copper-Catalyzed Synthesis of <i>β</i>-Keto Sulfones from Enol Silyl Ether and Sodium Arylsulfinates Open
β-Keto sulfones are an important group of sulfur-containing compounds and intermediates for organic synthesis, which are widely used in the construction of natural products and various important organic compounds.A method for the rapid syn…
View article: CCDC 2176172: Experimental Crystal Structure Determination
CCDC 2176172: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2195117: Experimental Crystal Structure Determination
CCDC 2195117: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Tandem Palladium/Copper-Catalyzed Decarboxylative Approach to Benzoimidazo- and Imidazophenanthridine Skeletons
Tandem Palladium/Copper-Catalyzed Decarboxylative Approach to Benzoimidazo- and Imidazophenanthridine Skeletons Open
A protocol for a tandem Pd/Cu-catalyzed intermolecular cross-coupling cascade between o-bromobenzoic acids and 2-(2-bromoaryl)-1H-benzo[d]imidazoles or the corresponding imidazoles is presented. The protocol provides conceptually novel and…
View article: Silver-Catalyzed Controlled Intermolecular Cross-Coupling of Silyl Enol Ethers: Scalable Access to 1,4-Diketones
Silver-Catalyzed Controlled Intermolecular Cross-Coupling of Silyl Enol Ethers: Scalable Access to 1,4-Diketones Open
A protocol for silver-catalyzed controlled intermolecular cross-coupling of silyl enolates is disclosed. The protocol displays good functional group tolerance and allows efficient preparation of a series of synthetically useful 1,4-diketon…
View article: Exploring Molecular Mechanisms of Aloe barbadmsis Miller on Diphenoxylate-Induced Constipation in Mice
Exploring Molecular Mechanisms of Aloe barbadmsis Miller on Diphenoxylate-Induced Constipation in Mice Open
Aloe barbadensis Miller (Aloe) known as a common succulent perennial herb had been traditionally used in constipation for more than 1,000 years. Aloe contained anthraquinones and other active compounds which had laxative effect and could m…
View article: Copper-assisted Wittig-type olefination of aldehydes with <i>p</i>-toluenesulfonylmethyl isocyanide
Copper-assisted Wittig-type olefination of aldehydes with <i>p</i>-toluenesulfonylmethyl isocyanide Open
A copper-assisted Wittig-type olefination of aldehydes and p -toluenesulfonyl isocyanide (TosMIC) is disclosed, providing an operationally simple approach to ( E )-vinyl sulfone with various functional groups under mild reaction conditions.
View article: Silver‐Catalyzed [3+1+1] Annulation of Nitrones with Isocyanoacetates as an Approach to 1,4,5‐Trisubstituted Imidazoles
Silver‐Catalyzed [3+1+1] Annulation of Nitrones with Isocyanoacetates as an Approach to 1,4,5‐Trisubstituted Imidazoles Open
A silver‐catalyzed protocol for [3+1+1] annulation of nitrones and isocyanoacetates is reported. The reaction is proposed to proceed through sequential [3+2] cycloaddition, ring‐opening, cyclization‐oxidation, and dealkylation, allowing ac…
View article: Switchable Copper-Catalyzed Approach to Benzodithiole, Benzothiaselenole, and Dibenzodithiocine Skeletons
Switchable Copper-Catalyzed Approach to Benzodithiole, Benzothiaselenole, and Dibenzodithiocine Skeletons Open
A copper-catalyzed reaction between 2-bromo-benzothioamides and S8 or Se involving sulfur rearrangement is reported, enabling access to benzodithioles 2 and benzothiaselenoles 6 in the presence of Cs2CO3. In the absence of S8 or Se, the re…
View article: CCDC 1995391: Experimental Crystal Structure Determination
CCDC 1995391: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1995392: Experimental Crystal Structure Determination
CCDC 1995392: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1915298: Experimental Crystal Structure Determination
CCDC 1915298: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1915237: Experimental Crystal Structure Determination
CCDC 1915237: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Silver-Assisted [3 + 2] Annulation of Nitrones with Isocyanides: Synthesis of 2,3,4-Trisubstituted 1,2,4-Oxadiazolidin-5-ones
Silver-Assisted [3 + 2] Annulation of Nitrones with Isocyanides: Synthesis of 2,3,4-Trisubstituted 1,2,4-Oxadiazolidin-5-ones Open
A silver-assisted method for [3 + 2] annulation of nitrones with isocyanides has been developed. The developed protocol allows access to a variety of 2,3,4-trisubstituted 1,2,4-oxadiazolidin-5-one derivatives as single diastereomers in goo…
View article: CCDC 1877566: Experimental Crystal Structure Determination
CCDC 1877566: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1863600: Experimental Crystal Structure Determination
CCDC 1863600: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1575618: Experimental Crystal Structure Determination
CCDC 1575618: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: An efficient green synthesis of 5 <i>H</i> -spiro[benzo[4,5]imidazo[1,2- <i>c</i> ]quinazoline-6,3′-indolin]-2′-ones catalyzed by iodine in ionic liquids
An efficient green synthesis of 5 <i>H</i> -spiro[benzo[4,5]imidazo[1,2- <i>c</i> ]quinazoline-6,3′-indolin]-2′-ones catalyzed by iodine in ionic liquids Open
Benzene-1,2-diamine was treated with 2-nitrobenzaldehyde in EtOH, and the product was reduced with hydrazine hydrate in the presence of Fe(C) without separation to give 2-(1 H -benzo[ d ]imidazol-2-yl)aniline ( 1 ). Reactions of compound 1…
View article: CCDC 1051562: Experimental Crystal Structure Determination
CCDC 1051562: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1438466: Experimental Crystal Structure Determination
CCDC 1438466: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …