Shangwei Chen
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View article: Phenylalanyl-tRNA synthetase subunit beta downregulation by spi1 proto-oncogene modulates lung adenocarcinoma progression and immune microenvironment via mammalian target of rapamycin pathway
Phenylalanyl-tRNA synthetase subunit beta downregulation by spi1 proto-oncogene modulates lung adenocarcinoma progression and immune microenvironment via mammalian target of rapamycin pathway Open
Background: Phenylalanyl-tRNA synthetase subunit beta (FARSB) is implicated in the progression of multiple cancers and represents a potential therapeutic target. However, its role in lung adenocarcinoma (LUAD) progression and the immune mi…
View article: Research on the Expression and Mechanism of LRRC8D in Esophageal Squamous Cell Carcinoma
Research on the Expression and Mechanism of LRRC8D in Esophageal Squamous Cell Carcinoma Open
Purpose The leucine-rich repeat-containing 8 (LRRC8) protein family, particularly leucine-rich repeat containing 8 family, member D (LRRC8D), has been implicated in various cancers. However, its role in esophageal squamous cell carcinoma (…
View article: Computed tomography-guided microwave ablation therapy for pediatric adrenal neuroblastoma with lung nodule a case report
Computed tomography-guided microwave ablation therapy for pediatric adrenal neuroblastoma with lung nodule a case report Open
This case suggests that MWA could be a valuable addition to existing treatment options for solid lesions in children.
View article: Associations between immune cell phenotypes and lung cancer subtypes: insights from mendelian randomization analysis
Associations between immune cell phenotypes and lung cancer subtypes: insights from mendelian randomization analysis Open
Introduction Lung cancer is a common malignant tumor, and different types of immune cells may have different effects on the occurrence and development of lung cancer subtypes, including lung squamous cell carcinoma (LUSC) and lung adenocar…
View article: Antioxidant Activities of Dihydromyricetin Derivatives with Different Acyl Donor Chain Lengths Synthetized by Lipozyme TL IM
Antioxidant Activities of Dihydromyricetin Derivatives with Different Acyl Donor Chain Lengths Synthetized by Lipozyme TL IM Open
Dihydromyricetin (DHM) is a phytochemical with multiple bioactivities. However, its poor liposolubility limits its application in the field. In this study, DHM was acylated with different fatty acid vinyl esters to improve its lipophilicit…
View article: Effects of Different Drying Methods on the Selenium Bioaccessibility and Antioxidant Activity of Cardamine violifolia
Effects of Different Drying Methods on the Selenium Bioaccessibility and Antioxidant Activity of Cardamine violifolia Open
Understanding the effects of drying on the selenium (Se) content and Se bioaccessibility of Se-rich plants is critical to dietary supplementation of Se. The effects of five common drying methods (far-infrared drying (FIRD), vacuum drying (…
View article: Temperature-Dependent Absorption of Ternary HfS2−xSex 2D Layered Semiconductors
Temperature-Dependent Absorption of Ternary HfS2−xSex 2D Layered Semiconductors Open
In this study, we present the investigation of optical properties on a series of HfS2−xSex crystals with different Se compositions x changing from 0 to 2. We used the chemical-vapor transport method to grow these layered ternary compound s…
View article: Highly Efficient Regioselective Acylation of Dihydromyricetin Catalyzed by Lipase in Nonaqueous Solvents
Highly Efficient Regioselective Acylation of Dihydromyricetin Catalyzed by Lipase in Nonaqueous Solvents Open
This study aimed to explore the enzymatic acylation of dihydromyricetin (DHM) to synthesized DHM derivatives with a different substituted carbon chain to improve its liposolubility. In the presence of Lipozyme TL IM, DHM was butyrylated in…
View article: The Clinical Significance of Forkhead Box M1 in Esophageal Squamous Cell Carcinoma Tissues: A Study Based on In-house Immunohistochemistry, RNA-sequencing, and Data Mining
The Clinical Significance of Forkhead Box M1 in Esophageal Squamous Cell Carcinoma Tissues: A Study Based on In-house Immunohistochemistry, RNA-sequencing, and Data Mining Open
BackgroundEsophageal squamous cell carcinoma (ESCC) ranks the sixth in mortality rates in cancers due to a lack of a specific target of diagnosis and treatment in the early stages. Although Forkhead box M1 (FOXM1) has been reported to be d…
View article: Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma
Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma Open
This study is aimed at thoroughly exploring the expression status, clinical significance, and underlying molecular mechanism of miRNA-33a-5p in lung squamous cell carcinoma (LUSC). Here, we detected miRNA-33a-5p in 20 samples from patients…
View article: Overexpression of cyclin‐dependent kinase 1 in esophageal squamous cell carcinoma and its clinical significance
Overexpression of cyclin‐dependent kinase 1 in esophageal squamous cell carcinoma and its clinical significance Open
Cyclin‐dependent kinase 1 (CDK1) plays a significant role in certain malignancies. However, it remains unclear whether CDK1 plays a role in esophageal squamous cell carcinoma (ESCC). The aim of this study was to analyze the expression and …
View article: The Indication of Poor Prognosis by High Expression of ENO1 in Squamous Cell Carcinoma of the Lung
The Indication of Poor Prognosis by High Expression of ENO1 in Squamous Cell Carcinoma of the Lung Open
The purpose of this study is to investigate the significance of alpha-enolase (ENO1) expression in squamous cell carcinoma of the lung (LUSC), its prognostic value, and prospective molecular mechanism. Using multiplatforms data, including …
View article: Efficient enzymatic modification of epigallocatechin gallate in ionic liquids
Efficient enzymatic modification of epigallocatechin gallate in ionic liquids Open
Epigallocatechin gallate (EGCG), the main polyphenolic substance in tea, exhibits well-known biological benefits. In order to improve fat solubility and bioavailability, a novel path for the lipase enzymatic transesterification synthesis o…
View article: Analysis of Wind-Resistant Ability and Failure Mode of Prefabricated WPC Enclosure Based on ABAQUS
Analysis of Wind-Resistant Ability and Failure Mode of Prefabricated WPC Enclosure Based on ABAQUS Open
In this paper, a prefabricated wood-plastic enclosure finite element analysis model, and its stress distribution under wind load and the failure mode of the enclosure under the maximum wind load bearing capacity are analyzed with the ABAQU…
View article: Antioxidant and anti-fatigue activities of selenium-enriched peptides isolated from Cardamine violifolia protein hydrolysate
Antioxidant and anti-fatigue activities of selenium-enriched peptides isolated from Cardamine violifolia protein hydrolysate Open
Cardamine violifolia is a selenium (Se)-enriched plant in China. In this study, we prepared Se-enriched peptides (SPE) from C. violifolia by enzymatic hydrolysis. The peptides were then separated by ultrafiltration. The fraction with the h…
View article: The Clinical Significance and Potential Molecular Mechanism of PTTG1 in Esophageal Squamous Cell Carcinoma
The Clinical Significance and Potential Molecular Mechanism of PTTG1 in Esophageal Squamous Cell Carcinoma Open
Esophageal squamous cell carcinoma (ESCC) is the major histological type of esophageal cancers worldwide. Transcription factor PTTG1 was seen highly expressed in a variety of tumors and was related to the degree of tumor differentiation, i…
View article: [Retracted] MEC‐Driven Fast Deformation Monitoring Based on GNSS Signal
[Retracted] MEC‐Driven Fast Deformation Monitoring Based on GNSS Signal Open
In the deformation monitoring based on satellite positioning, the extraction of the effective deformation signal which needs plenty of computing resources is very important. Mobile‐edge computing can provide low latency and near‐edge compu…
View article: Integrated expression analysis revealed RUNX2 upregulation in lung squamous cell carcinoma tissues
Integrated expression analysis revealed RUNX2 upregulation in lung squamous cell carcinoma tissues Open
This study aimed to investigate the clinicopathological significance and prospective molecular mechanism of RUNX family transcription factor 2 (RUNX2) in lung squamous cell carcinoma (LUSC). The authors used immunohistochemistry (IHC), RNA…
View article: Downregulation of miRNA‐126‐3p is associated with progression of and poor prognosis for lung squamous cell carcinoma
Downregulation of miRNA‐126‐3p is associated with progression of and poor prognosis for lung squamous cell carcinoma Open
Lung squamous cell carcinoma (LUSC) is the main pathological type of pulmonary malignant tumors; at present, less than 10% of patients with advanced metastatic LUSC live for more than 5 years. We previously reported that low expression of …
View article: The Clinical Significance and Potential Molecular Mechanisms of Synaptojanin 2 in Lung Adenocarcinoma
The Clinical Significance and Potential Molecular Mechanisms of Synaptojanin 2 in Lung Adenocarcinoma Open
Background Lung adenocarcinoma (LUAD) is the main pathological type of pulmonary malignant tumors. Synaptojanin 2 (SYNJ2), a member of the synaptojanin family, is considered as an attractive underlying therapeutic target in several types o…
View article: Increasing <scp>l</scp>-threonine production in <i>Escherichia coli</i> by overexpressing the gene cluster <i>phaCAB</i>
Increasing <span>l</span>-threonine production in <i>Escherichia coli</i> by overexpressing the gene cluster <i>phaCAB</i> Open
l-Threonine is an important branched-chain amino acid and could be applied in feed, drugs, and food. In this study, l-threonine production in an l-threonine-producing Escherichia coli strain TWF001 was significantly increased by overexpres…
View article: Research on Reasons for Repeated Falling of Tiles in Internal Walls of Construction
Research on Reasons for Repeated Falling of Tiles in Internal Walls of Construction Open
In view of the quality problem of repeated falling of facing tiles in some construction, the essay had a comparative trial in laboratory on cement mortar which is often used to paste tiles, special tile mortar and dry-hang glue, and measur…