Shanmugasundaram Nallasamy
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View article: Cheetah optimized CNN: A bio-inspired neural network for automated diabetic retinopathy detection
Cheetah optimized CNN: A bio-inspired neural network for automated diabetic retinopathy detection Open
The escalating global prevalence of diabetes has underscored the critical need for effective screening and diagnosis of diabetic retinopathy (DR), a common complication of diabetes that can lead to irreversible vision loss. In this study, …
View article: Energy‐efficient resource allocation model for device‐to‐device communication in 5G wireless personal area networks
Energy‐efficient resource allocation model for device‐to‐device communication in 5G wireless personal area networks Open
Summary In general, there are several many devices that can overload the network and reduce performance. Devices can minimize interference and optimize bandwidth usage by using directional antennas and by avoiding overlapping communication…
View article: L‐RUBI: An efficient load‐based resource utilization algorithm for bi‐partite scatternet in wireless personal area networks
L‐RUBI: An efficient load‐based resource utilization algorithm for bi‐partite scatternet in wireless personal area networks Open
Summary Recently, much of the wireless personal area network (WPAN) research concerns network protocols, scheduling, and security challenges but the major issue of resource utilization has been very rarely investigated. The design of resou…
View article: Progesterone and its receptor signaling in cervical remodeling: Mechanisms of physiological actions and therapeutic implications
Progesterone and its receptor signaling in cervical remodeling: Mechanisms of physiological actions and therapeutic implications Open
View article: Collagen and elastic fiber remodeling in the pregnant mouse myometrium
Collagen and elastic fiber remodeling in the pregnant mouse myometrium Open
The myometrium undergoes progressive tissue remodeling from early to late pregnancy to support fetal growth and transitions to the contractile phase to deliver a baby at term. Much of our effort has been focused on understanding the functi…
View article: Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy
Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy Open
Cervical remodeling is critical for a healthy pregnancy. The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation, transforming the tissue from a stiff material to a compliant, extensible, visco…
View article: RETRACTED: Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy
RETRACTED: Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy Open
View article: Transcriptome and proteome dynamics of cervical remodeling in the mouse during pregnancy
Transcriptome and proteome dynamics of cervical remodeling in the mouse during pregnancy Open
During gestation, the female reproductive tract must maintain pregnancy while concurrently preparing for parturition. Here, we explore the transitions in gene expression and protein turnover (fractional synthesis rates [FSR]) by which the …
View article: 733 The association of endoplasmic reticulum (ER) stress with labor and evidence of placental vascular malperfusion
733 The association of endoplasmic reticulum (ER) stress with labor and evidence of placental vascular malperfusion Open
View article: Msx Homeobox Genes Act Downstream of BMP2 to Regulate Endometrial Decidualization in Mice and in Humans
Msx Homeobox Genes Act Downstream of BMP2 to Regulate Endometrial Decidualization in Mice and in Humans Open
Endometrial stromal cells differentiate to form decidual cells in a process known as decidualization, which is critical for embryo implantation and successful establishment of pregnancy. We previously reported that bone morphogenetic prote…
View article: The mechanical response of the mouse cervix to tensile cyclic loading in term and preterm pregnancy
The mechanical response of the mouse cervix to tensile cyclic loading in term and preterm pregnancy Open
View article: Transcriptome signature identifies distinct cervical pathways induced in lipopolysaccharide-mediated preterm birth†,‡
Transcriptome signature identifies distinct cervical pathways induced in lipopolysaccharide-mediated preterm birth†,‡ Open
With half a million babies born preterm each year in the USA and about 15 million worldwide, preterm birth (PTB) remains a global health issue. Preterm birth is a primary cause of infant morbidity and mortality and can impact lives long pa…
View article: Distinct reorganization of collagen architecture in lipopolysaccharide-mediated premature cervical remodeling†
Distinct reorganization of collagen architecture in lipopolysaccharide-mediated premature cervical remodeling† Open
Previous work has identified divergent mechanisms by which cervical remodeling is achieved in preterm birth (PTB) induced by hormone withdrawal (mifepristone) or lipopolysaccharide (LPS). Our current study aims to document how collagen arc…
View article: Steroid Hormones Are Key Modulators of Tissue Mechanical Function via Regulation of Collagen and Elastic Fibers
Steroid Hormones Are Key Modulators of Tissue Mechanical Function via Regulation of Collagen and Elastic Fibers Open
The extracellular matrix (ECM) plays an active and dynamic role that both reflects and facilitates the functional requirements of a tissue. The mature ECM of the nonpregnant cervix is drastically reorganized during pregnancy to drive chang…
View article: Wnt/β-catenin signaling controls FGF synthesis in uterine stromal cells.
Wnt/β-catenin signaling controls FGF synthesis in uterine stromal cells. Open
A. Real-time PCR was performed to analyze the expression of Wnt ligands in uterine epithelial cells of Msx1f/fMsx2f/f and Msx1d/dMsx2d/d mice on day 4 of pregnancy. The level of …