Shannon M. Lynch
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View article: Associations Between Neighborhood Environment, Childhood Adversity, and Cancer Risk: A Geospatial Analysis
Associations Between Neighborhood Environment, Childhood Adversity, and Cancer Risk: A Geospatial Analysis Open
Objective Using a socio‐ecological perspective that includes consideration for the effects of the built environment, this study investigated the association between neighborhood‐level measures of childhood trauma, adult cancer prevention b…
View article: Investigation of Treatment‐Related Disparities in Metastatic Pancreatic Cancer Patients Using Real‐World Data
Investigation of Treatment‐Related Disparities in Metastatic Pancreatic Cancer Patients Using Real‐World Data Open
Background Racial disparities exist in the overall treatment of patients with metastatic pancreatic adenocarcinoma (mPDAC). Compared to White patients, patients of color are less likely to undergo surgical resection for early‐stage disease…
View article: Leveraging geospatial data to support an implementation science approach to address lung cancer burden
Leveraging geospatial data to support an implementation science approach to address lung cancer burden Open
The lung cancer mortality rate in Philadelphia is 16% higher than the national rate, making screening and prevention efforts paramount. To support prevention efforts, Fox Chase Cancer Center operates a comprehensive tobacco treatment progr…
View article: Racial/Ethnic Differences and Effects of Clinical/Socioeconomic Factors on Time from Diagnosis to Treatment in Pancreatic Cancer
Racial/Ethnic Differences and Effects of Clinical/Socioeconomic Factors on Time from Diagnosis to Treatment in Pancreatic Cancer Open
View article: Data-driven insights into neighborhood adherence to cancer prevention guidelines in Philadelphia
Data-driven insights into neighborhood adherence to cancer prevention guidelines in Philadelphia Open
Background Forty percent of new cancer cases in the United States are attributed to modifiable risks, which can be influenced by the built environment. Recent cancer prevention guidelines include recommendations for making communities cond…
View article: An exploratory analysis of the impact of area-level exposome on geographic disparities in aggressive prostate cancer
An exploratory analysis of the impact of area-level exposome on geographic disparities in aggressive prostate cancer Open
Numbers of aggressive prostate cancer (aPC) cases are rising, but only a few risk factors have been identified. In this study, we introduce a systematic approach to integrate geospatial data into external exposome research using aPC cases …
View article: Geographic Disparities in Cancer Incidence in the US Population Aged 20 to 49 Years, 2016–2020
Geographic Disparities in Cancer Incidence in the US Population Aged 20 to 49 Years, 2016–2020 Open
Preventing Chronic Disease (PCD) is a peer-reviewed electronic journal established by the National Center for Chronic Disease Prevention and Health Promotion. PCD provides an open exchange of information and knowledge among researchers, pr…
View article: A Novel Approach for Conducting a Catchment Area Analysis of Breast Cancer by Age and Stage for a Community Cancer Center
A Novel Approach for Conducting a Catchment Area Analysis of Breast Cancer by Age and Stage for a Community Cancer Center Open
Background: The U.S. Preventive Services Task Force recently issued an updated draft recommendation statement to initiate breast cancer screening at age 40, reflecting well-documented disparities in breast cancer–related mortality that dis…
View article: Factors Associated With Racial and Ethnic Disparities in Locally Advanced Rectal Cancer Outcomes
Factors Associated With Racial and Ethnic Disparities in Locally Advanced Rectal Cancer Outcomes Open
Importance Hispanic and non-Hispanic Black patients receiving neoadjuvant therapy and surgery for locally advanced rectal cancer (LARC) achieve less favorable clinical outcomes than non-Hispanic White patients, but the source of this dispa…
View article: Disparities in care of older adults of color with cancer: A narrative review
Disparities in care of older adults of color with cancer: A narrative review Open
This review describes the barriers and challenges faced by older adults of color with cancer and highlights methods to improve their overall care. In the next decade, cancer incidence rates are expected to increase in the United States for…
View article: Effect of neighborhood and individual-level socioeconomic factors on breast cancer screening adherence in a multi-ethnic study
Effect of neighborhood and individual-level socioeconomic factors on breast cancer screening adherence in a multi-ethnic study Open
View article: STREAMLINE: An Automated Machine Learning Pipeline for Biomedicine Applied to Examine the Utility of Photography-Based Phenotypes for OSA Prediction Across International Sleep Centers
STREAMLINE: An Automated Machine Learning Pipeline for Biomedicine Applied to Examine the Utility of Photography-Based Phenotypes for OSA Prediction Across International Sleep Centers Open
While machine learning (ML) includes a valuable array of tools for analyzing biomedical data, significant time and expertise is required to assemble effective, rigorous, and unbiased pipelines. Automated ML (AutoML) tools seek to facilitat…
View article: Development of a Multilevel Model to Identify Patients at Risk for Delay in Starting Cancer Treatment
Development of a Multilevel Model to Identify Patients at Risk for Delay in Starting Cancer Treatment Open
Importance Delays in starting cancer treatment disproportionately affect vulnerable populations and can influence patients’ experience and outcomes. Machine learning algorithms incorporating electronic health record (EHR) data and neighbor…
View article: Defining aggressive prostate cancer: a geospatial perspective
Defining aggressive prostate cancer: a geospatial perspective Open
Background Spatial analysis can identify communities where men are at risk for aggressive prostate cancer (PCan) and need intervention. However, there are several definitions for aggressive PCan. In this study, we evaluate geospatial patte…
View article: Trends in prostate cancer incidence among Black men in the Caribbean and the United States
Trends in prostate cancer incidence among Black men in the Caribbean and the United States Open
Background Prostate cancer incidence is highest for Black men of the African diaspora in the United States and Caribbean. Recent changes in recommendations for prostate cancer screening have been shown to decrease overall prostate cancer i…
View article: Current Status and Future Direction to Address Disparities in Diversity, Equity, and Inclusion in Prostate Cancer Care
Current Status and Future Direction to Address Disparities in Diversity, Equity, and Inclusion in Prostate Cancer Care Open
View article: Supplementary Tables 1-3 from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium
Supplementary Tables 1-3 from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium Open
Supplementary Tables 1-3 from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium
View article: Data from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium
Data from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium Open
A recent genome-wide association study (PanScan) identified significant associations at the ABO gene locus with risk of pancreatic cancer, but the influence of specific ABO genotypes remains unknown. We determined ABO genotypes (OO, AO, AA…
View article: Supplementary Tables 1-3 from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium
Supplementary Tables 1-3 from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium Open
Supplementary Tables 1-3 from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium
View article: Data from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium
Data from Pancreatic Cancer Risk and ABO Blood Group Alleles: Results from the Pancreatic Cancer Cohort Consortium Open
A recent genome-wide association study (PanScan) identified significant associations at the ABO gene locus with risk of pancreatic cancer, but the influence of specific ABO genotypes remains unknown. We determined ABO genotypes (OO, AO, AA…
View article: Neighborhood factors and triple negative breast cancer: The role of cumulative exposure to area‐level risk factors
Neighborhood factors and triple negative breast cancer: The role of cumulative exposure to area‐level risk factors Open
Background Despite similar incidence rates among Black and White women, breast cancer mortality rates are 40% higher among Black women. More than half of the racial difference in breast cancer mortality can be attributed to triple negative…
View article: Racial disparities in triple negative breast cancer: toward a causal architecture approach
Racial disparities in triple negative breast cancer: toward a causal architecture approach Open
Background Triple negative breast cancer (TNBC) is an aggressive subtype of invasive breast cancer that disproportionately affects Black women and contributes to racial disparities in breast cancer mortality. Prior research has suggested t…
View article: Variation in Cancer Incidence Rates Among Non-Hispanic Black Individuals Disaggregated by Nativity and Birthplace, 2005-2017: A Population-Based Cancer Registry Analysis
Variation in Cancer Incidence Rates Among Non-Hispanic Black Individuals Disaggregated by Nativity and Birthplace, 2005-2017: A Population-Based Cancer Registry Analysis Open
Objectives Compared to other racial and ethnic groups, little to no disaggregated cancer incidence data exist for subgroups of non-Hispanic Blacks (NHBs), despite heterogeneity in sociodemographic characteristics and cancer risk factors wi…
View article: Systematic review of neighborhood socioeconomic indices studied across the cancer control continuum
Systematic review of neighborhood socioeconomic indices studied across the cancer control continuum Open
Background There is extensive interest in understanding how neighborhood socioeconomic status (nSES) may affect cancer incidence or survival. However, variability regarding items included and approaches used to form a composite nSES index …
View article: Examining socio-spatial mobility patterns among colon cancer patients after diagnosis
Examining socio-spatial mobility patterns among colon cancer patients after diagnosis Open
Given the growing number of cancer survivors, it is important to better understand socio-spatial mobility patterns of cancer patients after diagnosis that could have public health implications regarding post-diagnostic access to care for t…
View article: Racial Disparities in Triple Negative Breast Cancer: Toward a Causal Architecture Approach
Racial Disparities in Triple Negative Breast Cancer: Toward a Causal Architecture Approach Open
Background: Triple negative breast cancer (TNBC) is an aggressive subtype of invasive breast cancer that disproportionately affects Black women and contributes to racial disparities in breast cancer mortality. Prior research has suggested …
View article: TELEHEALTH PROVIDER PERSPECTIVES DURING COVID-19: INSIGHTS FROM AN ACADEMIC CARDIOLOGY PRACTICE
TELEHEALTH PROVIDER PERSPECTIVES DURING COVID-19: INSIGHTS FROM AN ACADEMIC CARDIOLOGY PRACTICE Open
View article: Measuring Neighborhood Landscapes: Associations between a Neighborhood’s Landscape Characteristics and Colon Cancer Survival
Measuring Neighborhood Landscapes: Associations between a Neighborhood’s Landscape Characteristics and Colon Cancer Survival Open
Landscape characteristics have been shown to influence health outcomes, but few studies have examined their relationship with cancer survival. We used data from the National Land Cover Database to examine associations between regional-stag…
View article: LCS-DIVE: An Automated Rule-based Machine Learning Visualization Pipeline for Characterizing Complex Associations in Classification
LCS-DIVE: An Automated Rule-based Machine Learning Visualization Pipeline for Characterizing Complex Associations in Classification Open
Machine learning (ML) research has yielded powerful tools for training accurate prediction models despite complex multivariate associations (e.g. interactions and heterogeneity). In fields such as medicine, improved interpretability of ML …
View article: Effect of Neighborhood and Individual-Level Socioeconomic Factors on Colorectal Cancer Screening Adherence
Effect of Neighborhood and Individual-Level Socioeconomic Factors on Colorectal Cancer Screening Adherence Open
Despite the effectiveness of screenings in reducing colorectal cancer (CRC) mortality, ~25% of US adults do not adhere to screening guidelines. Prior studies associate socioeconomic status (SES) with low screening adherence and suggest tha…