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Pathologic Response to Immunotherapy is Associated with Survival in Patients Undergoing Delayed Nephrectomy for Metastatic Renal Cell Carcinoma Open

Yash S. Khandwala, Stephen W. Reese, Burçin Ağrıdağ Üçpınar, Andrea Knežević, Lennert Eismann , et al. · 2025

Introduction The role of consolidative nephrectomy (CN) in metastatic renal cell carcinoma (mRCC) patients treated with immune checkpoint inhibitors (ICIs) remains unknown. As patients derive variable benefit from immunotherapy (IO), under…

Surgical outcomes of cytoreductive nephrectomy in patients receiving systemic immunotherapy for advanced renal cell carcinoma Open

Stephen W. Reese, Lennert Eismann, Charlie White, Juan Arroyave Villada, Sari Khaleel , et al. · 2023

Follicular lymphoma presenting as a seminal vesicle mass: Diagnostic path from prostate MRI to 18F-FDG PET/CT Open

Burçin Ağrıdağ Üçpınar, Stephen W. Reese, Lennert Eismann, Ömer Aras · 2023

Prognostic Factors for Survival in Patients Undergoing Surveillance After Cytoreductive Nephrectomy Open

Stephen W. Reese, Sari Khaleel, Andrew W. Silagy, Amy Xie, Lennert Eismann , et al. · 2023

Using risk stratification based on IMDC and number of metastatic sites, surveillance in favorable-risk patients can be utilized for a period without the initiation of systemic therapy. This approach can delay patients' exposure to the side…

Supplementary Table 2 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 65KB, Cancer cells were treated with DPS for 4 hr under normoxia (NO) or hypoxia (HO), and the proliferation was measured by clonogenic assay.

Supplementary Table 2 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 65KB, Cancer cells were treated with DPS for 4 hr under normoxia (NO) or hypoxia (HO), and the proliferation was measured by clonogenic assay.

Supplementary Table 4 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 223KB, RT-qPCR validation of microarray data.

Supplementary Table 3 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 66KB, Serum biochemistry panel.

Supplementary Figures 1 - 9 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 1660KB, S1 Mouse body weight change in response to DPS treatment; S2. DPS did not induce autophagy in HI-LAPC-4 cells; S3: DPS did not induce cell cycle arrest; S4: DPS did not enhance IR-induced DNA damage; S5: DPS activity on s…

Supplementary Table 4 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 223KB, RT-qPCR validation of microarray data.

Data from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

Purpose: Hypoxia is an important characteristic of the solid tumor microenvironment and constitutes a barrier for effective radiotherapy. Here, we studied the effects of darinaparsin (an arsenic cytotoxin) on survival and radiosensi…

Supplementary Figures 1 - 9 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 1660KB, S1 Mouse body weight change in response to DPS treatment; S2. DPS did not induce autophagy in HI-LAPC-4 cells; S3: DPS did not induce cell cycle arrest; S4: DPS did not enhance IR-induced DNA damage; S5: DPS activity on s…

Supplementary Figure Legend from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 79KB.

Supplementary Table 3 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 66KB, Serum biochemistry panel.

Supplementary Table 1 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

XLS file, 83KB.

Supplementary Figure Legend from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

PDF file, 79KB.

Data from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

Purpose: Hypoxia is an important characteristic of the solid tumor microenvironment and constitutes a barrier for effective radiotherapy. Here, we studied the effects of darinaparsin (an arsenic cytotoxin) on survival and radiosensi…

Supplementary Table 1 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer Open

Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah Young , et al. · 2023

XLS file, 83KB.

Advances in Imaging-Based Biomarkers in Renal Cell Carcinoma: A Critical Analysis of the Current Literature Open

Lina Posada Posada Calderon, Lennert Eismann, Stephen W. Reese, Ed Reznik, A. Ari Hakimi · 2023

Cross-sectional imaging is the standard diagnostic tool to determine underlying biology in renal masses, which is crucial for subsequent treatment. Currently, standard CT imaging is limited in its ability to differentiate benign from malig…

Immune checkpoint inhibitor monotherapy is associated with less cardiac toxicity than combination therapy Open

Eugene B. Cone, Lorine Haeuser, Stephen W. Reese, Maya Marchese, David‐Dan Nguyen , et al. · 2022

Background Treatment options for many cancers include immune checkpoint inhibitor (ICI) monotherapy and combination therapy with impressive clinical benefit across cancers. We sought to define the comparative cardiac risks of ICI combinati…

872P Ipilimumab-induced gastrointestinal and hepatic immune-related adverse events: A national cohort Open

Bjoern Langbein, Muhieddine Labban, Xin Chen, Stephen W. Reese, S. Lipsitz , et al. · 2022

Immune Checkpoint Inhibitor Monotherapy is Associated With Less Cardiac Toxicity Than Combination Therapy Open

Eugene B. Cone, Lorine Haeuser, Stephen W. Reese, Maya Marchese, David‐Dan Nguyen , et al. · 2021

Background: Treatment options for many cancers include immune checkpoint inhibitor (ICI) monotherapy and combination therapy with impressive clinical benefit across cancers. We sought to define the comparative cardiac risks of ICI combinat…

Cardiovascular toxicities associated with abiraterone compared to enzalutamide–A pharmacovigilance study Open

Eugene B. Cone, Stephen W. Reese, Maya Marchese, Junaid Nabi, Rana R. McKay , et al. · 2021

Recovery from minimally invasive vs. open surgery in kidney cancer patients: Opioid use and workplace absenteeism Open

Marieke J. Krimphove, Stephen W. Reese, Xi Chen, Maya Marchese, Daniel Pucheril , et al. · 2020

Patients undergoing various forms of surgery for kidney cancer had lower rates of peri-operative opioid use, fewer days of workplace absenteeism, but no difference in long-term rates of opioid use in patients undergoing minimally invasive …

Insights from Pharmacovigilance: Gastrointestinal-Related Immune Checkpoint Inhibitor Adverse Events Open

Stephen W. Reese, Maya Marchese, Julia McNabb‐Baltar · 2020

Temporal trends in the incidence of testicular cancer in the United States over the past four decades Open

Stephen W. Reese, Karl H. Tully, Junaid Nabi, Marco Paciotti, Eugene B. Cone , et al. · 2020

Lower odds of cardiac events for gonadotropic releasing hormone antagonists versus agonists Open

Eugene B. Cone, Daniele Modonutti, Stephen W. Reese, Maya Marchese, Junaid Nabi , et al. · 2020

Abiraterone is associated with higher odds of cardiac complications compared to enzalutamide Open

Eugene B. Cone, Daniele Modonutti, Stephen W. Reese, Maya Marchese, Junaid Nabi , et al. · 2020

Comparison of surgical complications requiring intervention in open vs. minimally invasive radical prostatectomy Open

Lorine Haeuser, Marco Paciotti, Stephen W. Reese, Richard D. Urman, Joachim Noldus , et al. · 2020

Checkpoint inhibitor monotherapy is associated with less cardiac toxicity than combination therapy Open

Eugene B. Cone, Lorine Haeuser, Stephen W. Reese, Maya Marchese, Junaid Nabi , et al. · 2020

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