Shanshan Shi
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View article: Air pollutants, road traffic noise, and incidence of valvular heart disease: A UK Biobank-based prospective study
Air pollutants, road traffic noise, and incidence of valvular heart disease: A UK Biobank-based prospective study Open
Air and noise pollution are recognized public health concerns. However, their long-term impact on valvular heart disease (VHD) remains unclear. This study analyzed 453,413 participants from the UK Biobank. Air pollution was quantified usin…
View article: Development of a nomogram model for predicting coronary heart disease in patients with metabolic-associated fatty liver disease
Development of a nomogram model for predicting coronary heart disease in patients with metabolic-associated fatty liver disease Open
Objective To investigate the risk factors associated with coronary heart disease (CHD) in patients with metabolic-associated fatty liver disease (MAFLD) and develop a nomogram prediction model. Methods This study included 394 patients with…
View article: Loss of G-protein coupled receptor 68 in hematopoietic tissues enhances long-term hematopoietic stem cell function upon aging
Loss of G-protein coupled receptor 68 in hematopoietic tissues enhances long-term hematopoietic stem cell function upon aging Open
View article: A rare case of bilateral elastofibroma dorsi of the back with postoperative subthoracic seroma: Case report
A rare case of bilateral elastofibroma dorsi of the back with postoperative subthoracic seroma: Case report Open
Rationale: Elastofibroma dorsi is a slow-growing, ill-defined benign soft tissue tumor characterized by excessive proliferation of fibroblast tissue. Tumors are made up of collagen and coarse elastic fibers. At present, the pathogenesis is…
View article: Red‐Light Triggered CO/ROS Release from Porphyrin‐Flavonol Hybrid@PC7A Micelles for Eradicating <i>Escherichia coli</i>
Red‐Light Triggered CO/ROS Release from Porphyrin‐Flavonol Hybrid@PC7A Micelles for Eradicating <i>Escherichia coli</i> Open
Photo‐triggered carbon monoxide (CO) release, mediated by reactive oxygen species (ROS), shows a significant potential in therapeutic applications. However, the existing photosensitizers predominantly function as type II ROS generators. Wh…
View article: Short-term outcomes and risk factors for mortality in neonatal cardiac surgeries with cardiopulmonary bypass: a 5-year single-center report
Short-term outcomes and risk factors for mortality in neonatal cardiac surgeries with cardiopulmonary bypass: a 5-year single-center report Open
Background Open-heart surgeries carry significantly greater risks in neonates than in older children. The current study aimed to analyze the short-term outcomes and risk factors for mortality in neonates undergoing cardiac surgeries. Metho…
View article: Coronary recanalization following spring coil occlusion: A case report and literature review
Coronary recanalization following spring coil occlusion: A case report and literature review Open
Rationale: Coronary artery perforation (CAP) is one of the most serious complications of percutaneous coronary intervention. Coronary arteriovenous fistula is a considerably rare type of congenital CAP. They are usually difficult to distin…
View article: Klippel–Trenaunay syndrome with multiorgan vascular involvement and gastrointestinal bleeding: A case report and literature review
Klippel–Trenaunay syndrome with multiorgan vascular involvement and gastrointestinal bleeding: A case report and literature review Open
Rationale: To explore the early diagnosis and treatment of Klippel–Trenaunay syndrome (KTS), and provide useful and systematic clinical references for the diagnosis and treatment of such congenital vascular malformations combined with long…
View article: Corneal nerve abnormalities in early-stage diabetic retinopathy evaluated by corneal confocal microscopy
Corneal nerve abnormalities in early-stage diabetic retinopathy evaluated by corneal confocal microscopy Open
View article: The Predictive and Prognostic Value of the Systemic Immune-Inflammation Index for Congestive Heart Failure
The Predictive and Prognostic Value of the Systemic Immune-Inflammation Index for Congestive Heart Failure Open
Background: The systemic immune-inflammatory index (SII), calculated by (platelet count × neutrophil count)/lymphocyte count, is a novel biomarker with predive and prognostic value in numerous diseases. However, the relationship between SI…
View article: Development and Application of Offshore Trade Authenticity Verification Platform Based on Blockchain
Development and Application of Offshore Trade Authenticity Verification Platform Based on Blockchain Open
Offshore trade is a widely used business model in international trade, but because of its opaque capital flow, transaction information is not open, offshore trade has certain risks. In order to guarantee the national economic security and …
View article: Electrochemiluminescent Quenching of Luminol Dopped Zr-Mof for Application of Atp Detection Through Scavenging ROS by Gallic Acid Capped AU Nanoparticles
Electrochemiluminescent Quenching of Luminol Dopped Zr-Mof for Application of Atp Detection Through Scavenging ROS by Gallic Acid Capped AU Nanoparticles Open
View article: Trim-Away in adult animals through Nano-ERASER and its application in cancer therapy
Trim-Away in adult animals through Nano-ERASER and its application in cancer therapy Open
Trim-Away is a versatile intracellular protein degradation pathway that has been extensively explored in vitro . However, the in vivo application of Trim-Away is limited at oocyte and zygote stages due to the lack of an in vivo practical a…
View article: Polymer/copper nanocomplex-induced lysosomal cell death promotes tumor lymphocyte infiltration and synergizes anti-PD-L1 immunotherapy for triple-negative breast cancer
Polymer/copper nanocomplex-induced lysosomal cell death promotes tumor lymphocyte infiltration and synergizes anti-PD-L1 immunotherapy for triple-negative breast cancer Open
The PDA-PEG/copper nanocomplex kills 4T1 cells by lysosomal cell death and exhibits a synergetic effect with the PD-L1 antibody through ICD-boosted T-cell infiltration.
View article: Perioperative extracorporeal membrane oxygenation in pediatric congenital heart disease: Chinese expert consensus
Perioperative extracorporeal membrane oxygenation in pediatric congenital heart disease: Chinese expert consensus Open
View article: A Therapeutic Sheep in Metastatic Wolf’s Clothing: Trojan Horse Approach for Cancer Brain Metastases Treatment
A Therapeutic Sheep in Metastatic Wolf’s Clothing: Trojan Horse Approach for Cancer Brain Metastases Treatment Open
View article: Elongated soy protein isolate-poly(D, L-lactide-co-glycolic acid) microcapsules prepared using syringe filters and their effect on self-healing efficiency of soy protein-based green resin
Elongated soy protein isolate-poly(D, L-lactide-co-glycolic acid) microcapsules prepared using syringe filters and their effect on self-healing efficiency of soy protein-based green resin Open
A self-healing soy-based resin filled with soy protein isolate (SPI) containing poly(D, L-lactide-co-glycolic acid) (PLGA) microcapsules (MCs) was prepared. MCs were prepared using a syringe filter via a membrane emulsification technique. …
View article: Esterase‐Activatable and Glutathione‐Responsive Triptolide Nano‐Prodrug for the Eradication of Pancreatic Cancer
Esterase‐Activatable and Glutathione‐Responsive Triptolide Nano‐Prodrug for the Eradication of Pancreatic Cancer Open
Triptolide (TPL) is a small molecule isolated from a traditional Chinese herb Tripterygium wilfordii Hook F and shows excellent anticancer effect for pancreatic cancer cells. However, the poor water solubility ad severe liver toxicity of T…
View article: Carrier‐Free Nanoassembly of Curcumin–Erlotinib Conjugate for Cancer Targeted Therapy
Carrier‐Free Nanoassembly of Curcumin–Erlotinib Conjugate for Cancer Targeted Therapy Open
Anticancer drug‐loaded nanoparticles have been explored extensively to decrease side effects while improving their therapeutic efficacy. However, due to the low drug loading content, premature drug release, nonstandardized carrier structur…
View article: Enhanced Photothermal Therapy through the In Situ Activation of a Temperature and Redox Dual‐Sensitive Nanoreservoir of Triptolide
Enhanced Photothermal Therapy through the In Situ Activation of a Temperature and Redox Dual‐Sensitive Nanoreservoir of Triptolide Open
Photothermal therapy (PTT) has attracted tremendous attention due to its noninvasiveness and localized treatment advantages. However, heat shock proteins (HSPs) associated self‐preservation mechanisms bestow cancer cells thermoresistance t…
View article: Synthesis, Crystal Structures, and Photoluminescent Properties of Two Supramolecular Architectures Based on Difunctional Ligands Containing Imidazolyl and Carboxyl Groups
Synthesis, Crystal Structures, and Photoluminescent Properties of Two Supramolecular Architectures Based on Difunctional Ligands Containing Imidazolyl and Carboxyl Groups Open
Two new supramolecular architectures, namely, [Cd(L1)2(H2O)]n (1) and [Ni(L2)2(H2O)]n (2), were synthesized by the reaction of corresponding metal salts of CdCl2·2.5H2O and NiCl2·6H2O with 2-(1H-imidazol-4-yl)benzoic acid (HL1) and 3-(1H-i…
View article: Synthesis, Crystal Structures, and Properties of a New Supramolecular Polymer Based on Mixed Imidazole and Carboxylate Ligands
Synthesis, Crystal Structures, and Properties of a New Supramolecular Polymer Based on Mixed Imidazole and Carboxylate Ligands Open
One new coordination polymer, namely, [Cd3(H2L)3(Pza)2(H2O)2]n (1) was synthesized by the reaction of Cd(NO3)2·4H2O with 1,4-di(1H-imidazol-4-yl)benzene (H2L) and 3,5-pyrazoledicarboxylic acid (H3pza) and characterized by single-crystal X-…
View article: Synthesis, Crystal Structures, and Properties of Two Coordination Polymers Built from Imidazolyl and Carboxylate Ligands
Synthesis, Crystal Structures, and Properties of Two Coordination Polymers Built from Imidazolyl and Carboxylate Ligands Open
Two new two-dimensional (2D) layer coordination polymers—namely, [Cd(L)2]n (1) and [Co(L)2(H2O)]n (2)—were synthesized by the reaction of corresponding metal salts with 3-(1H-imidazol-4-yl)benzoic acid (HL) incorporating 4-imidazolyl and c…