Shaoyong Peng YOU? Author Swipe

Last 10y

Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade Open

Shaoyong Peng, Minhao Wu, Yan Qian, Gaopo Xu, Yumo Xie , et al. · 2025

Background Immunotherapy is beneficial for some colorectal cancer (CRC) patients, but immunosuppressive networks limit its effectiveness. Cancer‐associatedfibroblasts (CAFs) are significant in immune escape and resistance toimmunotherapy, …

Laparoscopic functional fundoplication: a seven-step anti-reflux technique guided by Membrane anatomy landmarks Open

Yingru Li, Zhou Taicheng, Shuang Chen, Zhilong Yuan, Fuheng Liu , et al. · 2025

Gamma-glutamyl transferase to aspartate aminotransferase ratio (GSR) predicts prognoses in patients with colorectal cancer with liver metastasis after microwave ablation Open

Mingzhe Huang, Zhiliang Chen, Si Qin, Jiaming Zhou, Yan Huang , et al. · 2024

Gamma-glutamyl Transferase to Aspartate Aminotransferase Ratio (GSR) Predicts Prognoses in Patients with Colorectal Cancer with Liver Metastasis after Microwave Ablation Open

Mingzhe Huang, Zhiliang Chen, Si Qin, Jiaming Zhou, Yan Huang , et al. · 2024

Background Microwave ablation (MWA) is widely used to eliminate colorectal liver metastases (CRLM). However, the risk of tumor recurrence is difficult to predict due to lack of reliable clinical and biological markers. Elevation of gamma-g…

Replenishment of mitochondrial Na+ and H+ by ionophores potentiates cutaneous wound healing in diabetes Open

Liangliang Bai, Linping Wu, Changsheng Zhang, Zhiwen Liu, Liang Ma , et al. · 2024

Diabetic foot ulcer (DFU) is a highly morbid complication in patients with diabetes mellitus, necessitating the development of innovative pharmaceuticals to address unmet medical needs. Sodium ion (Na⁺) is a well-established med…

RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner Open

Dingcheng Shen, Jinxin Lin, Yumo Xie, Zhuokai Zhuang, Gaopo Xu , et al. · 2023

Background N6‐methyladenosine (m6A) modification is an emerging epigenetic regulatory mechanism in tumourigenesis. Considering that AlkB homolog 5 (ALKBH5) is a well‐described m6A demethylase in previous enzyme assays, we aimed to investig…

Supplementary Data from Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer Open

Yingjie Li, Liangliang Bai, Huichuan Yu, Du Cai, Xiaolin Wang , et al. · 2023

Supplemental Figures 1-10 and Reagent table

Supplementary Table 1 from Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer Open

Yingjie Li, Liangliang Bai, Huichuan Yu, Du Cai, Xiaolin Wang , et al. · 2023

Table S1. The distribution and calculated pI of peptides in the peptide arrays

Supplementary Table 1 from Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer Open

Yingjie Li, Liangliang Bai, Huichuan Yu, Du Cai, Xiaolin Wang , et al. · 2023

Table S1. The distribution and calculated pI of peptides in the peptide arrays

Data from Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer Open

Yingjie Li, Liangliang Bai, Huichuan Yu, Du Cai, Xiaolin Wang , et al. · 2023

DNA methylation contributes to malignant transformation, but little is known about how the methylation drives colorectal cancer evolution at the early stages. Here we identify aberrant INA (α-internexin) gene methylation in colon adenoma a…

Data from Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer Open

Yingjie Li, Liangliang Bai, Huichuan Yu, Du Cai, Xiaolin Wang , et al. · 2023

DNA methylation contributes to malignant transformation, but little is known about how the methylation drives colorectal cancer evolution at the early stages. Here we identify aberrant INA (α-internexin) gene methylation in colon adenoma a…

Supplementary Data from Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer Open

Yingjie Li, Liangliang Bai, Huichuan Yu, Du Cai, Xiaolin Wang , et al. · 2023

Supplemental Figures 1-10 and Reagent table

Radiological lymph‐node size improves the prognostic value of systemic inflammation index in rectal cancer with pathologically negative nodes Open

Shaoyong Peng, Xiaoxia Liu, Yingjie Li, Huichuan Yu, Yumo Xie , et al. · 2023

Background The relationship between the radiological lymph node (rLN) size and survival outcome in node‐negative rectal cancer is still uncertain. In this study, we aimed to explore the role of enlarged rLN in predicting the survival of no…

Fasting-mimicking diet synergizes with ferroptosis against quiescent, chemotherapy-resistant cells Open

Xiaoxia Liu, Shaoyong Peng, Guannan Tang, Gaopo Xu, Yumo Xie , et al. · 2023

Prevalent Pseudoprogression and Pseudoresidue in Patients With Rectal Cancer Treated With Neoadjuvant Immune Checkpoint Inhibitors Open

Yumo Xie, Jinxin Lin, Ning Zhang, Xiaolin Wang, Puning Wang , et al. · 2023

Background: Immune checkpoint inhibitor (ICI) treatment in patients with microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) tumors holds promise in reshaping organ preservation in rectal cancer. However, the benefits ar…

Silence of a dependence receptor CSF1R in colorectal cancer cells activates tumor-associated macrophages Open

Mingxuan Zhu, Liangliang Bai, Xiaoxia Liu, Shaoyong Peng, Yumo Xie , et al. · 2022

Background Colony-stimulating factor 1 receptor (CSF1R), a classic tyrosine kinase receptor, has been identified as a proto-oncogene in multiple cancers. The CSF1/CSF1R axis is essential for the survival and differentiation of M2-phenotype…

Development and external validation of prognostic nomograms for liver disease-free and overall survival in locally advanced rectal cancer with neoadjuvant therapy: a post cohort study based on the FOWARC trial Open

Jiaming Zhou, Tuoyang Li, Yuanlv Xiao, Jinxin Lin, Xiaoqiong Chen , et al. · 2022

The nomograms established in this study can effectively predict LDFS and has good clinical application potential for OS in LARC patients treated with neoadjuvant therapy.

Analysis of Prognostic Factors of Colorectal Cancer Liver Metastasis after Microwave Ablation Open

Shuyun Tan, Pinzhu Huang, Shaoyong Peng, Jiaming Zhou, Guangjian Liu , et al. · 2022

Objective: To investigate the risk factors associated with intrahepatic recurrence and survival after microwave ablation (MWA) for colorectal cancer with liver metastases. Methods: Retrospective analysis of clinical, patholo…

Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity Open

Shaoyong Peng, Yingjie Li, Meijin Huang, Guannan Tang, Yumo Xie , et al. · 2022

Patients with peritoneal metastasis (PM) of colorectal cancer (CRC) have poorer overall survival outcomes than those without PM. Cancer-associated fibroblasts (CAFs) are a major component of the tumor microenvironment and mediate CRC progr…

ORMDL1 is upregulated and associated with favorable outcomes in colorectal cancer Open

Qian Wang, Wanjun Liu, Si Chen, Qianxin Luo, Yichen Li , et al. · 2021

HBV Infection Statuses Indicate Different Risks of Synchronous and Metastasis Liver Metastasis in Colorectal Cancer Open

Jiaming Zhou, Pinzhu Huang, Xiaoyan Guo, Shuyun Tan, Rongwan Lin , et al. · 2021

Background: Previous studies on the effect of HBV infection on CRLM are contrary. This study identified more specific and different impacts of HBV on CRLM. Methods: A total of 3132 CRC patients were analyzed retrospectively and followed up…

Enhancing cancer‐associated fibroblast fatty acid catabolism within a metabolically challenging tumor microenvironment drives colon cancer peritoneal metastasis Open

Shaoyong Peng, Daici Chen, Jian Cai, Zixu Yuan, Binjie Huang , et al. · 2021

Most cancer‐related deaths result from the progressive growth of metastases. Patients with peritoneal metastatic (PM) colorectal cancer have reduced overall survival. Currently, it is still unclear why colorectal cancer (CRC) cells home to…

ORMDL1 is Upregulated and Associated With Favorable Outcome in Colorectal Cancer Open

Qian Wang, Wanjun Liu, Si Chen, Qianxin Luo, Yichen Li , et al. · 2021

Background: ORMDL1 gene encodes a transmembrane protein for endoplasmic reticulum and is known as crucial negative regulator for sphingolipid biogenesis. However, it has been rarely studied in tumor-related context. Therefore, its prognost…

Synthesis and pharmacological characterization of glucopyranosyl-conjugated benzyl derivatives as novel selective cytotoxic agents against colon cancer Open

Boqiao Fu, Yingjie Li, Shaoyong Peng, Xiaolin Wang, Jingying Hu , et al. · 2021

Glucopyranosyl-conjugated benzyl derivatives containing a [1,2,3]-triazole linker were synthesized. Benzyl served as an important pharmacophore in anti-cancer compounds. Compound 8d inhibited the proliferation of colorectal cancer cells wi…

ORMDL1 is upregulated and associated with favorable outcome in colorectal cancer Open

Qian Wang, Wanjun Liu, Si Chen, Qianxin Luo, Yichen Li , et al. · 2020

Background ORMDL1 gene encodes a transmembrane protein for endoplasmic reticulum and is known as crucial negative regulator for sphingolipid biogenesis. However, it has been rarely studied in tumor-related context. Therefore, its prognosti…

Decreased expression of SorCS1 in colorectal cancer: An independent predictor of poor prognosis Open

P. Z. Huang, Shaoyong Peng, Huichuan Yu, Lihong Huang, Qi Yao , et al. · 2019

Previously, we identified that sortilin related VPS10 domain containing receptor 1 (SorCS1) was hypermethylated in colorectal cancer (CRC) tissues. Here, we aimed to investigate the association between CRC and SorCS1. DNA methylation was d…

Prognostic value of preoperative carcinoembryonic antigen/tumor size in rectal cancer Open

Du Cai, Zenghong Huang, Huichuan Yu, Xiaolin Wang, Liangliang Bai , et al. · 2019

Preoperative CEA/tumor size is an independent prognostic factor for patients with stage I-III rectal cancer. Higher CEA/tumor size is associated with worse OS and DFS.

The combination of the glycolysis inhibitor 2-DG and sorafenib can be effective against sorafenib-tolerant persister cancer cells Open

Li Wang, Qian Yang, Shaoyong Peng, Xiaoxia Liu · 2019

These findings suggest that such a combination can effectively hamper persister cell growth and may represent a promising therapeutic strategy to prevent persister cell resistance.

Meta-analysis of the effectiveness of laparoscopic adjustable gastric banding versus laparoscopic sleeve gastrectomy for obesity Open

Laiyuan Li, Huichuan Yu, Jinglin Liang, Yinyin Guo, Shaoyong Peng , et al. · 2019

Background: Laparoscopic adjustable gastric banding (LAGB) and laparoscopic sleeve gastrectomy (LSG) are common weight loss procedures. Our meta-analysis compared these procedures for the treatment of morbid obesity and related diseases. M…

Prognostic value of carcinoembryonic antigen level in patients with colorectal cancer liver metastasis treated with percutaneous microwave ablation under ultrasound guidance Open

Shaoyong Peng, Pinzhu Huang, Huichuan Yu, Yanlin Wen, Yanxin Luo , et al. · 2018

Thermal ablation is an alternative treatment for colorectal cancer liver metastasis (CRLM). However, prognostic factors in patients with CRLM who have undergone microwave ablation (MWA) have not been clearly defined. Therefore, this study …

Fetching topic information...