Explanipedia

One Step Closer to Conversational Medical Records: ChatGPT Parses Psoriasis Treatments from EMRs Open

Jonathan Shapiro, Mor Atlas, Sharon Baum, Felix Pavlotsky, A Barzilai , et al. · 2025

Large Language Models (LLMs), such as ChatGPT, are increasingly used in clinical settings, including documentation and decision support. However, their accuracy in extracting treatment data from unstructured dermatology records remains und…

Long-term Durability of Narrowband Ultraviolet B-induced Repigmentation in Non-segmental Vitiligo: A Retrospective Study Open

Riad Kassem, Ilya Vaynshteyn, Aviv Barzilai, Assaf Handelsman, Alon Scope , et al. · 2025

Narrowband ultraviolet B (NB-UVB) phototherapy is a well-established vitiligo treatment. However, limited data exist on the long-term effects of NB-UVB-induced repigmentation. This study evaluated the long-term durability of repigmentation…

Vasculitis as an indicator of disease severity in familial Mediterranean fever Open

Aviv Barzilai, Yarin Mash, Rotem Gershon, Elon Pras, Sharon Baum · 2025

Introduction Various types of vasculitides have been identified in patients with familial Mediterranean fever (FMF); however, FMF characteristic in patients who experience vasculitis during the disease course have not been described. This …

Prognostic Factors Predicting Remission Following Rituximab Therapy for Pemphigus Vulgaris Open

Tal Raviv, Keren Pevzner, Aviv Barzilai, Felix Pavlotsky, Sharon Baum · 2025

Pemphigus vulgaris is a chronic autoimmune blistering disease with significant morbidity. Rituximab, approved as its first-line treatment, effectively induces remission. However, few studies have analysed the prognostic factors for improve…

Association of Adult Atopic Dermatitis with Impaired Oral Health and Oral Dysbiosis: A Case-Control Study Open

Aaya Shahin, Yael A. Leshem, Yossi Taieb, Sharon Baum, Aviv Barzilai , et al. · 2024

The role of piperacillin/tazobactam in the treatment of Hidradenitis suppurativa Open

Aviv Barzilai, Shir Toubiana, Adam Dalal, Sharon Baum · 2024

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. Most patients with moderate-to-severe disease require long-term antibiotic treatment, or biologic treatments to control their disease. Despite these i…

Diagnosis, treatment, and long‐term outcomes of pediatric pemphigus: a retrospective study at tertiary medical centers Open

Yael Renert‐Yuval, Sharon Baum, Shoshana Greenberger, Eran Cohen‐Barak, Meital Oren‐Shabtai , et al. · 2024

Background Pediatric pemphigus is a rare bullous disease that represents a diagnostic and therapeutic challenge; evidence on patients' response to various treatments and long‐term surveillance data are lacking. We aimed to investigate pedi…

Comparison of Intralesional Sodium Stibogluconate versus Intralesional Meglumine Antimoniate for the Treatment of Leishmania major Cutaneous Leishmaniasis Open

Michal Solomon, Ayelet Ollech, Felix Pavlotsky, Aviv Barzilai, Eli Schwartz , et al. · 2024

Israel is endemic for Old-World cutaneous leishmaniasis. The most common species is Leishmania major. However, the available treatment options are limited. This study’s objective was to compare the authors’ experience with different antimo…

Biological treatment for bullous pemphigoid Open

Meital Oren‐Shabtai, Daniel Mimouni, Adi Nosrati, Lihi Atzmony, Baruch Kaplan , et al. · 2023

Background Bullous pemphigoid (BP) is the most common autoimmune subepidermal bullous disease. Topical or systemic corticosteroids are often used as the first-line treatment. However, long-term corticosteroid use may lead to significant si…

Prevalence, Spectrum and Clinical Implications of Malignancies in Patients with Bullous Pemphigoid Open

Sharon Baum, Shani Steinberg, Ido Tzanani, Aviv Barzilai, Anna Lyakhovitsky · 2023

Current research on the malignancy rate and spectrum of malignancies in patients with bullous pemphigoid is contradictory. The aims of this study were to determine the prevalence and spectrum of malignancy in patients with bullous pemphigo…

Safety of COVID-19 mRNA vaccination in children with chronic urticaria Open

Catherine Zhu, Alex Nguyen, Connor Prosty, Sofianne Gabrielli, Vera Laboccetta , et al. · 2023

Skin Eosinophil Counts in Bullous Pemphigoid as a Prognostic Factor for Disease Severity and Treatment Response Open

Sharon Baum, Maya Engler Markowitz, Anna Lyakhovitsky, Rotem Gershon, Hannah Aviv , et al. · 2022

Dermal infiltration of eosinophils and eosinophilic spongiosis are prominent features of bullous pemphigoid lesions. Although several observations support the pathogenic role of eosinophils in bullous pemphigoid, few studies have examined …

Rifampin plus Clindamycin vs. Tetracyclines for Hidradenitis Suppurativa Open

Vashurin Ilan, Aviv Barzilai, Sharon Baum, Zehavi Keren-Or, Ilan Vashurin · 2022

Introduction: Hidradenitis suppurativa (HS) is a chronic, painful, follicular occlusive disease that affects the follicular pilosebaceous unit.It is typically apparent in intertriginous areas, causing abscesses, sinus tract formation, and …

Relationship Between Pemphigus Vulgaris Severity and PCR-positive Herpes Simplex Virus Open

Sharon Baum, Itai Atar, Dan Coster, Sara Dovrat, Michal Solomon , et al. · 2022

Pemphigus vulgaris is a rare autoimmune skin disease. Although herpes simplex virus has been associated with autoimmune diseases, evidence regarding its association with pemphigus vulgaris exacerbations is scarce. This retrospective cohort…

Efficacy of Systemic Treatment for Leishmania tropica Cutaneous Leishmaniasis Open

Michal Solomon, Shoshana Greenberger, Maya Milner, Felix Pavlotzky, Aviv Barzilai , et al. · 2022

The effectiveness of systemic treatment for Leishmania tropica cutaneous leishmaniasis remains unclear. The purpose of the study is to evaluate the efficacy and safety of systemic treatments for L. tropica cutaneous leishmaniasis. This ret…

Validation of the Urticaria Control Test (UCT) in Children with Chronic Urticaria Open

Connor Prosty, Sofianne Gabrielli, Pasquale Mulé, Nuzha Noorah, Sharon Baum , et al. · 2022

Background No validated tools exist to evaluate chronic urticaria (CU) control in children. While the Urticaria Control Test (UCT) exhibits favourable clinometric properties in adult CU, it is not yet validated in children. Therefore, we s…

Author response for "Biomarkers associated with chronic spontaneous urticaria severity in 108 children" Open

Lydia Zhang, Michelle Le, Sofianne Gabrielli, Elena Netchiporouk, Gregory Gooding , et al. · 2021

Increased Prevalence of Autoimmune Diseases in Children with Chronic Spontaneous Urticaria Open

Michelle Le, Lydia Zhang, Sofianne Gabrielli, Elena Netchiporouk, Sharon Baum , et al. · 2021

Reply to “Comment on: ‘Children with chronic urticaria can be effectively controlled with updosing second-generation antihistamines’” Open

Sofianne Gabrielli, Michelle Le, Elena Netchiporouk, Barbara Miedzybrodzki, Sharon Baum , et al. · 2020

Dermatomyositis–lupuslike syndrome overlap under treatment with etanercept for rheumatoid arthritis Open

Anna Lyakhovitsky, Karin Warshavsky, Lihi Rozner, Theodoulos Drousiotis, Sharon Baum , et al. · 2020

Chronic urticaria in children can be controlled effectively with updosing second-generation antihistamines Open

Sofianne Gabrielli, Michelle Le, Elena Netchiporouk, Barbara Miedzybrodzki, Sharon Baum , et al. · 2020

Establishing a New Mastocytosis Registry in Canada Open

Mahdi Hassan, Elena Netchiporouk, Sofianne Gabrielli, Greg Shand, Elinor Simons , et al. · 2020

Efficacy of Repeated Courses of Rituximab as Treatment for Pemphigus Vulgaris Open

Sharon Baum, Tal Raviv, Sarit Gilboa, Felix Pavlotsky, Aviv Barzilai · 2020

Rituximab targets the B-lymphocyte antigen CD20, providing pemphigus vulgaris patients with long-term remissions. However, the effects of repeated courses have not yet been established. This study aimed to evaluate the effect of repeated r…

Diagnosis and management of pemphigus: Recommendations of an international panel of experts Open

Dédée F. Murrell, S.M. Peña, P. Joly, Branka Marinović, Takashi Hashimoto , et al. · 2018

Patterns of local site reactions to subcutaneous glatiramer acetate treatment of multiple sclerosis: a clinicopathological study. Open

Aviv Barzilai, Yaron Zafrir, Anat Achiron, Sharon Baum · 2018

Background: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system. Glatiramer acetate (GA) is a commonly used immunomodulating drug. It is administered subcutaneously and is usually well tolerated;…

Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene Open

Dan Vodo, Ofer Sarig, Shamir Geller, Edna Ben‐Asher, Tsviya Olender , et al. · 2016

Pemphigus vulgaris (PV) is a life-threatening autoimmune mucocutaneous blistering disease caused by disruption of intercellular adhesion due to auto-antibodies directed against epithelial components. Treatment is limited to immunosuppressi…

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