John P. Cheatham
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View article: 1-Year Outcomes in a Pooled Cohort of Harmony Transcatheter Pulmonary Valve Clinical Trial Participants
1-Year Outcomes in a Pooled Cohort of Harmony Transcatheter Pulmonary Valve Clinical Trial Participants Open
The Harmony TPV device demonstrated favorable clinical and hemodynamic outcomes across studies and valve types through 1 year. Further follow-up will continue to assess long-term valve performance and durability.
View article: O-5 | Two-Year Outcomes in an Expanded Cohort of Harmony Transcatheter Pulmonary Valve Recipients
O-5 | Two-Year Outcomes in an Expanded Cohort of Harmony Transcatheter Pulmonary Valve Recipients Open
The Harmony transcatheter pulmonary valve (TPV) is the first FDA-approved device for severe pulmonary regurgitation (PR) in the native or surgically repaired right ventricular outflow tract (RVOT). Our objective was to evaluate 2-year safe…
View article: O-6 | One-Year Outcomes in an Expanded Cohort of Harmony Transcatheter Pulmonary Valve Recipients
O-6 | One-Year Outcomes in an Expanded Cohort of Harmony Transcatheter Pulmonary Valve Recipients Open
BackgroundThe Harmony transcatheter pulmonary valve (TPV) is designed to treat severe pulmonary regurgitation (PR) in the native or surgically repaired right ventricular outflow tract (RVOT). Our objective was to evaluate 1-year safety and…
View article: Long-Term Outcomes After Melody Transcatheter Pulmonary Valve Replacement in the US Investigational Device Exemption Trial
Long-Term Outcomes After Melody Transcatheter Pulmonary Valve Replacement in the US Investigational Device Exemption Trial Open
Background: The Melody valve was developed to extend the useful life of previously implanted right ventricular outflow tract (RVOT) conduits or bioprosthetic pulmonary valves, while preserving RV function and reducing the lifetime burden o…
View article: Comparison of the investigational device exemption and post‐approval trials of the Melody transcatheter pulmonary valve
Comparison of the investigational device exemption and post‐approval trials of the Melody transcatheter pulmonary valve Open
Objective We compared 5‐year outcomes of transcatheter pulmonary valve (TPV) replacement with the Melody TPV in the post‐approval study (PAS) and the investigational device exemption (IDE) trial. Background As a condition of approval of th…
View article: Spontaneous reversal of stenosis in tissue-engineered vascular grafts
Spontaneous reversal of stenosis in tissue-engineered vascular grafts Open
Computational modeling and ovine data reveal spontaneous reversal of early tissue-engineered vascular graft stenosis, with clinical implications.
View article: Pulmonary Regurgitation – Results from the Harmony™ Transcatheter Pulmonary Valve Trial
Pulmonary Regurgitation – Results from the Harmony™ Transcatheter Pulmonary Valve Trial Open
View article: Gene Delivery for Limb-Girdle Muscular Dystrophy Type 2D by Isolated Limb Infusion
Gene Delivery for Limb-Girdle Muscular Dystrophy Type 2D by Isolated Limb Infusion Open
In a previous limb-girdle muscular dystrophy type 2D (LGMD2D) clinical trial, robust alpha-sarcoglycan gene expression was confirmed following intramuscular gene (SGCA) transfer. This paved the way for first-in-human isolated limb infusion…
View article: An Isolated Limb Infusion Method Allows for Broad Distribution of rAAVrh74.MCK.GALGT2 to Leg Skeletal Muscles in the Rhesus Macaque
An Isolated Limb Infusion Method Allows for Broad Distribution of rAAVrh74.MCK.GALGT2 to Leg Skeletal Muscles in the Rhesus Macaque Open
Recombinant adeno-associated virus (rAAV)rh74.MCK.GALGT2 is a muscle-specific gene therapy that is being developed to treat forms of muscular dystrophy. Here we report on an isolated limb infusion technique in a non-human primate model, wh…
View article: Continuous Assessment of a Stented Coronary Artery Using a Pressure Wire During Percutaneous Pulmonary Valve Implantation
Continuous Assessment of a Stented Coronary Artery Using a Pressure Wire During Percutaneous Pulmonary Valve Implantation Open
A 52-year-old woman with tetralogy of Fallot status post-complete surgical repair with infundibular resection, pulmonary valvotomy, and patch closure of the ventricular septal defect presented with severe pulmonary regurgitation and depres…
View article: Percutaneous Patent Ductus Arteriosus (PDA) Closure in Very Preterm Infants: Feasibility and Complications
Percutaneous Patent Ductus Arteriosus (PDA) Closure in Very Preterm Infants: Feasibility and Complications Open
Background Percutaneous closure of patent ductus arteriosus ( PDA ) in term neonates is established, but data regarding outcomes in infants born very preterm (<32 weeks of gestation) are minimal, and no published criteria exist establishin…
View article: Changes in right ventricular function in neonates with hypoplastic left heart syndrome before and after the hybrid procedure
Changes in right ventricular function in neonates with hypoplastic left heart syndrome before and after the hybrid procedure Open
Systolic and diastolic functions decreased after the hybrid procedure despite the fact that patients avoided cardiopulmonary bypass. These results are comparable with previous reports in HLHS patients undergoing the Norwood procedure. Furt…
View article: Accuracy of Imaging Modalities in Detection of Baffle Leaks in Patients Following Atrial Switch Operation
Accuracy of Imaging Modalities in Detection of Baffle Leaks in Patients Following Atrial Switch Operation Open
Aims Patients with dextro‐transposition of the great arteries (d‐ TGA ) status post atrial switch operation are vulnerable to complications such as baffle leaks. The best noninvasive imaging modality to detect baffle leaks is unknown. The …