Sharon Karan
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View article: Screening and evaluation of chickpea (Cicer arietinum L.) genotypes for salinity stress tolerance: A biochemical, physiological and yield assessment
Screening and evaluation of chickpea (Cicer arietinum L.) genotypes for salinity stress tolerance: A biochemical, physiological and yield assessment Open
Chickpea (Cicer arietinum L.), an important legume crop extensively cultivated across India, is adversely affected by a range of biotic and abiotic stresses, with soil salinity being a major factor that significantly reduces its productivi…
View article: Reasons for Composite Restoration Replacement in an Iranian Population
Reasons for Composite Restoration Replacement in an Iranian Population Open
Background: This study aimed to assess the reasons for composite restoration replacement in patients in Ahwaz, Iran. Materials and Methods: This cross-sectional study was conducted on 231 patients presenting to the dental clinic of the Sch…
View article: Safety, pharmacokinetics and pharmacodynamics of obeticholic acid in subjects with fibrosis or cirrhosis from NASH
Safety, pharmacokinetics and pharmacodynamics of obeticholic acid in subjects with fibrosis or cirrhosis from NASH Open
Background & Aims Fibrosis stage is a strong predictor of nonalcoholic steatohepatitis (NASH) outcomes. Two blinded studies evaluated the pharmacokinetics, pharmacodynamics and safety of obeticholic acid (OCA) in subjects with staged NASH …
View article: Composition Of Soil Mesofauna In Changing Cropping Systems Due To Urbanization In Bengaluru, India
Composition Of Soil Mesofauna In Changing Cropping Systems Due To Urbanization In Bengaluru, India Open
The study focused on the composition of soil mesofauna within changing cropping systems influenced by urbanization in Bengaluru, Karnataka, India during the rabi season of 2020–2021. Four major cropping systems, namely pulses, vegetables, …
View article: Assessment of Pharmacokinetic Interactions Between Obeticholic Acid and Caffeine, Midazolam, Warfarin, Dextromethorphan, Omeprazole, Rosuvastatin, and Digoxin in Phase 1 Studies in Healthy Subjects
Assessment of Pharmacokinetic Interactions Between Obeticholic Acid and Caffeine, Midazolam, Warfarin, Dextromethorphan, Omeprazole, Rosuvastatin, and Digoxin in Phase 1 Studies in Healthy Subjects Open
Intercept Pharmaceuticals, Inc.
View article: Parent‐Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT‐888), a PARP Inhibitor, in Patients With <i>BRCA 1/2</i>–Mutated Cancer or PARP‐Sensitive Tumor Types
Parent‐Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT‐888), a PARP Inhibitor, in Patients With <i>BRCA 1/2</i>–Mutated Cancer or PARP‐Sensitive Tumor Types Open
Veliparib (ABT‐888) is a novel oral poly‐ADP‐ribose polymerase (PARP) inhibitor that is being developed for the treatment of hematologic malignancies and solid tumors. Although the pharmacokinetics of veliparib have been studied in combina…