Sharon Roesner
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View article: Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout aging
Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout aging Open
Mitochondrial genomes co-evolve with the nuclear genome over evolutionary timescales and are shaped by selection in the female germline. Here, we investigate how mismatching between nuclear and mitochondrial ancestry impacts the somatic ev…