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View article: Comparison of Plasma Metagenomic Next-generation Sequencing and PCR Methods for Epstein–Barr Virus Viral Load Monitoring in Nasopharyngeal Carcinoma
Comparison of Plasma Metagenomic Next-generation Sequencing and PCR Methods for Epstein–Barr Virus Viral Load Monitoring in Nasopharyngeal Carcinoma Open
Harish N. Vasudevan, Ann A. Lazar, Kevin Reyes, Dezhi Rong, Shaun Arevalo , et al. · 2024
Plasma mNGS is a distinct method for EBV titer measurement in NPC patients and more broadly, is a promising method for non-invasive monitoring of disease status for infection-associated malignancies.
View article: Detection of Neoplasms by Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid
Detection of Neoplasms by Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid Open
Wei Gu, Andreas M. Rauschecker, Elaine Hsu, Kelsey C. Zorn, Yasemin Sucu , et al. · 2021
This case-control study showed that CSF mNGS, which has low specimen volume requirements, does not require the preservation of cell integrity, and was orginally developed to diagnose neurologic infections, can also detect genetic evidence …
View article: Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids
Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids Open
Wei Gu, Eric Talevich, Elaine Hsu, Zhongxia Qi, Anatoly Urisman , et al. · 2021
View article: Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid
Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid Open
Wei Gu, Andreas M. Rauschecker, Elaine Hsu, Kelsey C. Zorn, Yasemin Sucu , et al. · 2021
Importance Malignant neoplasms of the central nervous system (CNS) are frequently not detected by cerebrospinal fluid (CSF) flow cytometry or cytology, and clinical phenotypes can overlap with inflammatory meningoencephalitis. Objective To…
View article: Detection of Cryptogenic Malignancies from Metagenomic Whole Genome Sequencing of Body Fluids
Detection of Cryptogenic Malignancies from Metagenomic Whole Genome Sequencing of Body Fluids Open
Wei Gu, Eric Talevich, Elaine Hsu, Zhongxia Qi, Anatoly Urisman , et al. · 2021
Detection of Cryptogenic Malignancies from Metagenomic Whole Genome Sequencing of Body Fluids Wei Gu1,2,3,4*, Eric Talevich5, Elaine Hsu1, Zhongxia Qi1, Anatoly Urisman6
View article: Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid
Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid Open
Wei Gu, Andreas M. Rauschecker, Elaine Hsu, Kelsey C. Zorn, Yasemin Sucu , et al. · 2021
Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid Wei Gu, MD, PhD1,2*, Andreas M. Rauschecker, MD, PhD3, Elaine Hsu, BS1, Kelsey C. Zorn, BS4, Yasemin Sucu, BS1, …
View article: Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid
Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid Open
Wei Gu, Andreas M. Rauschecker, Elaine Hsu, Kelsey C. Zorn, Yasemin Sucu , et al. · 2021
Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid Wei Gu1,2*, Andreas M. Rauschecker3, Elaine Hsu1, Kelsey C. Zorn4, Yasemin Sucu1, Scot Federman1, All…
View article: Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid
Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid Open
Wei Gu, Andreas M. Rauschecker, Elaine Hsu, Kelsey C. Zorn, Yasemin Sucu , et al. · 2021
Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid Wei Gu, MD, PhD1,2*, Andreas M. Rauschecker, MD, PhD3, Elaine Hsu, BS1, Kelsey C. Zorn, BS4, Yasemin Sucu, BS1, …
View article: Additional file 2 of Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids
Additional file 2 of Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids Open
Wei Gu, Eric Talevich, Elaine Hsu, Zhongxia Qi, Anatoly Urisman , et al. · 2021
Additional file 2: Table S1. Body fluid samples from patients positive for malignancy by cytology and/or flow cytometry.
View article: Additional file 3 of Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids
Additional file 3 of Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids Open
Wei Gu, Eric Talevich, Elaine Hsu, Zhongxia Qi, Anatoly Urisman , et al. · 2021
Additional file 3: Table S2. Select microbiological cases that have overlapping features with cancer presentations.
View article: Additional file 4 of Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids
Additional file 4 of Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids Open
Wei Gu, Eric Talevich, Elaine Hsu, Zhongxia Qi, Anatoly Urisman , et al. · 2021
Additional file 4: Table S3. Microbiological cases - all other cases.
View article: Additional file 5 of Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids
Additional file 5 of Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids Open
Wei Gu, Eric Talevich, Elaine Hsu, Zhongxia Qi, Anatoly Urisman , et al. · 2021
Additional file 5: Table S4. Verification cohort.
View article: Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids
Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids Open
Wei Gu, Xianding Deng, Marco Lee, Yasemin Sucu, Shaun Arevalo , et al. · 2020
View article: Rapid deployment of SARS-CoV-2 testing: The CLIAHUB
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB Open
Emily Crawford, Irene Acosta, Vida Ahyong, Erika C. Anderson, Shaun Arevalo , et al. · 2020
Author(s): Crawford, Emily D; Acosta, Irene; Ahyong, Vida; Anderson, Erika C; Arevalo, Shaun; Asarnow, Daniel; Axelrod, Shannon; Ayscue, Patrick; Azimi, Camillia S; Azumaya, Caleigh M; Bachl, Stefanie; Bachmutsky, Iris; Bhaduri, Aparna; Br…
View article: Direct Comparison of SARS-CoV-2 Analytical Limits of Detection across Seven Molecular Assays
Direct Comparison of SARS-CoV-2 Analytical Limits of Detection across Seven Molecular Assays Open
Becky Fung, Allan Gopez, Venice Servellita, Shaun Arevalo, Coral Ho , et al. · 2020
Analytical sensitivity for SARS-CoV-2 detection is a key performance metric for the evaluation of viral detection assays. We determined analytical limits of detection for seven SARS-CoV-2 assays using serial dilutions of pooled patient mat…
View article: Author Correction: Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance
Author Correction: Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance Open
Xianding Deng, Asmeeta Achari, Scot Federman, Guixia Yu, Sneha Somasekar , et al. · 2020
View article: Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance
Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance Open
Xianding Deng, Asmeeta Achari, Scot Federman, Guixia Yu, Sneha Somasekar , et al. · 2020
View article: LB14. Cerebrospinal Fluid Profiling of the Human Host Response Reveals Species-Specific Enterovirus Biosignatures in Acute Flaccid Myelitis Cases
LB14. Cerebrospinal Fluid Profiling of the Human Host Response Reveals Species-Specific Enterovirus Biosignatures in Acute Flaccid Myelitis Cases Open
Benjamin Briggs, Yale Santos, Akshaya Ramesh, Manfred Grabherr, Asmeeta Achari , et al. · 2019
Background Since 2014 there have been global biennial outbreaks of acute flaccid myelitis (AFM), a rare but severe “polio-like” illness of as yet-unknown etiology primarily affecting children. Enteroviruses (EVs),, especially EV-D68 and EV…
View article: Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis
Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis Open
Michael R. Wilson, Hannah A. Sample, Kelsey C. Zorn, Shaun Arevalo, Guixia Yu , et al. · 2019
Routine microbiologic testing is often insufficient to detect all neuroinvasive pathogens. In this study, metagenomic NGS of CSF obtained from patients with meningitis or encephalitis improved diagnosis of neurologic infections and provide…
View article: Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid
Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid Open
Steve Miller, Samia N. Naccache, Erik Samayoa, Kevin Messacar, Shaun Arevalo , et al. · 2019
Metagenomic next-generation sequencing (mNGS) for pan-pathogen detection has been successfully tested in proof-of-concept case studies in patients with acute illness of unknown etiology but to date has been largely confined to research set…
View article: Laboratory Validation of a Clinical Metagenomic Sequencing Assay for Pathogen Detection in Cerebrospinal Fluid
Laboratory Validation of a Clinical Metagenomic Sequencing Assay for Pathogen Detection in Cerebrospinal Fluid Open
Steve Miller, SN Naccache, Erik Samayoa, Kevin Messacar, Shaun Arevalo , et al. · 2018
Metagenomic next-generation sequencing (mNGS) for pan-pathogen detection has been successfully tested in proof-of-concept case studies in patients with acute illness of unknown etiology, but to date has been largely confined to research se…
View article: Diagnosis of Fatal Human Case of St. Louis Encephalitis Virus Infection by Metagenomic Sequencing, California, 2016
Diagnosis of Fatal Human Case of St. Louis Encephalitis Virus Infection by Metagenomic Sequencing, California, 2016 Open
Charles Y. Chiu, Lark L. Coffey, Jamie A. Murkey, Kelly Symmes, Hannah A. Sample , et al. · 2017
We used unbiased metagenomic next-generation sequencing to diagnose a fatal case of meningoencephalitis caused by St. Louis encephalitis virus in a patient from California in September 2016. This case is associated with the recent 2015-201…




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