Shaymaa Elsayed
YOU?
Author Swipe
Electrophysiologic study of upper extremity peripheral nerves following arteriovenous access creation in end stage renal disease patients Open
Background and aims Arteriovenous fistula (AVF) creation is a surgical procedure that involves connecting an artery and a vein, typically in the forearm or upper arm. This alteration in blood flow dynamics can indeed lead to nerve-related …
View article: Pediatric hyperthyroidism and its therapeutic outcomes: A comprehensive comparative review of Graves’ Disease, Hashimoto’s Thyroiditis, and Hashitoxicosis
Pediatric hyperthyroidism and its therapeutic outcomes: A comprehensive comparative review of Graves’ Disease, Hashimoto’s Thyroiditis, and Hashitoxicosis Open
Background: Pediatric hyperthyroidism, predominantly caused by Graves’ disease (GD), is a rare endocrine disorder but has serious impacts with systemic consequences that extend beyond thyroid hormone excess. Despite the availability of ant…
Genetic and acquired microcephaly in children: Integrating medical etiologies, imaging, clinical features, and prognosis Open
Background: Microcephaly is a neurodevelopmental disorder characterized by a head circumference more than two standard deviations below the mean for age and sex. It encompasses a spectrum of genetic (primary) and acquired (secondary) cause…
View article: Short stature with elevated IGF-1: Diagnostic pitfalls and growth hormone therapy outcomes across etiologies
Short stature with elevated IGF-1: Diagnostic pitfalls and growth hormone therapy outcomes across etiologies Open
Background: Short stature in children is typically linked to low insulin-like growth factor 1 (IGF-1), reflecting growth hormone (GH) deficiency or nutritional deprivation. However, a distinct and diagnostically challenging subgroup presen…
Macrocephaly in children: A comprehensive review of etiologies, MRI features, clinical, biochemical, genetic correlates, and prognostic implications Open
Background: Macrocephaly, defined as a head circumference >+2 SD for age and sex, is a common pediatric finding with a wide differential diagnosis. While often benign, it can signal underlying genetic syndromes, metabolic disorders, neurod…
An Update on 3M Syndrome: Review of Clinical and Molecular Aspects and Report of Additional Families Open
3M syndrome is a rare autosomal recessive disorder characterized by short stature and recognizable facial and musculoskeletal features. Pathogenic variants in the CUL7 , OBSL1 , and CCDC8 genes are implicated in the pathogenesis of 3M synd…
View article: Managing persistent neonatal hyperinsulinemic hypoglycemia: Insights from nesidioblastosis research
Managing persistent neonatal hyperinsulinemic hypoglycemia: Insights from nesidioblastosis research Open
Background: Persistent neonatal hyperinsulinemic hypoglycemia (PNHH), frequently associated with nesidioblastosis, poses significant diagnostic and therapeutic challenges due to dysregulated insulin secretion. Congenital hyperinsulinism (C…
Differential impact of glucose abnormalities and iron overload in TM (TM) and TI(TI): A comparative analysis of diagnostic approaches and management strategies for optimized care Open
Introduction: Thalassemia syndromes, specifically TM (TM) and TI(TI), are inherited blood disorders characterized by impaired hemoglobin synthesis, leading to chronic anemia. TM requires frequent blood transfusions, causing iron overload a…
Insulin-induced lipodystrophy and predisposing factors in children and adolescents with type 1 diabetes mellitus (T1DM) in a tertiary care Egyptian center. Open
Improper insulin injection technique, older age, and longer duration of T1DM were associated with LH. Proper education of patients and their parents must include correct injection techniques, rotating injection sites, and minimal reuse of …
Insulin-induced Lipo hypertrophy and factors affecting it in children and adolescents with type 1 diabetes mellitus: Review of Literature in the past 12 years Open
Lipohypertrophy (LD) is one of the most common complications of subcutaneous insulin injection. Many factors are convicted in the development and progress of LD in children with T1DM. Lipodystrophy can worsen glycemic control in these chil…
Insulin-induced Lipo hypertrophy and factors affecting it in children and adolescents with type 1 diabetes mellitus: Review of Literature in the past 12 years Open
Lipohypertrophy (LD) is one of the most common complications of subcutaneous insulin injection. Many factors are convicted in the development and progress of LD in children with T1DM. Lipodystrophy can worsen glycemic control in these chil…
Impact of Disorders of Sex Development on Egyptian Parents and Factors Affecting Them Open
Background: Disorders of sex development (DSD) are a category of congenital diseases characterized by aberrant internal and external genital structure development. Parental adjustment and functioning have been highlighted as being at risk …
Clinical and molecular characteristics of infantile-onset diabetes mellitus in Egypt Open
Purpose: In patients diagnosed with diabetes mellitus (DM) before the age of 12 months, there is an increasing recognition of diabetes caused by single-gene mutations, also known as monogenic diabetes of infancy or neonatal DM (NDM). This …
Evaluation of the early outcomes of partial urogenital sinus mobilization in females with congenital adrenal hyperplasia Open
Background Congenital adrenal hyperplasia (CAH) is the most common cause of ambiguous genitalia with an incidence of 1 in 15,000 live births. Surgical reconstruction for girls with CAH and urogenital sinus (UGS) is a great challenge to cre…